Associations of body composition at birth and accretion from 0-5 years with kidney function and volume at the 10-year follow-up: the Ethiopian iABC birth cohort.

Background: Fat mass (FM) and fat-free mass (FFM) in early life are associated with later obesity and cardio-metabolic disease. This study aimed to assess the associations of FM and FFM at birth and conditional FM and FFM accretion from 0-5 years with kidney outcomes at the 10-year follow-up.

Method: The Ethiopian Infant Anthropometry and Body Composition (iABC) birth cohort included term infants born in Jimma town, with a birth weight ≥1500 grams, and having no congenital malformations.

Effect of double-duty interventions on double burden of malnutrition among adolescents in Debre Berhan Regiopolitan City, Ethiopia: a cluster randomised controlled trial.

Combating the double burden of malnutrition (DBM) in adolescents is a critical public health challenge in low-income countries like Ethiopia. However, past efforts have lacked focus and exhibited diverse governance strategies. Therefore, this study assesses the effect of selected double-duty interventions (DDIs) on DBM among adolescents in Central Ethiopia.

Animal source food consumption and anaemia among school adolescent girls in Silti District, Central Ethiopia: a public health perspective.

Animal source foods (ASFs) are diverse and heterogeneous, including unprocessed red meat, processed meat, poultry, eggs, seafood, milk, cheese, and yoghurt. It is essential for preventing malnutrition and its consequences among vulnerable populations, including infants, young children, adolescents, women of reproductive age, and pregnant and lactating women. Understanding the intakes of ASF among adolescents and associated factors is critical for establishing priorities to promote its consumption and enhance growth and development during this period.

Nutritional status and associated factors among adult tuberculosis patients in public health centres of Horro Guduru Wollega Zone, Oromia Region, Western Ethiopia.

This study aimed to assess nutritional status and associated factors among adult tuberculosis patients in public health centres in Horro Guduru Wollega Zone, Western Ethiopia, 2021. An institutional-based cross-sectional study was conducted among 334 randomly selected adult TB patients at public health centres from May 7, 2021, to June 21, 2021. Data were collected using structured questionnaires and anthropometric measurements.

Associations of early childhood exposure to severe acute malnutrition and recovery with cardiometabolic risk markers in later childhood: 5-year prospective matched cohort study in Ethiopia.

Background: Impaired fetal and accelerated postnatal growth are associated with cardiometabolic disease. Few studies investigated how recovery from severe acute malnutrition (SAM) is associated with childhood cardiometabolic risk.

Objective: We evaluated cardiometabolic risk in SAM children treated through community-based management, relative to controls, 5-year post-recovery.

A rare case of sclerosing angiomatoid nodular transformation of spleen: A case report.

Introduction And Importance: Sclerosing angiomatoid nodular transformation of the spleen is a rare benign vascular lesion arising from red pulp of spleen with unknown etiopathogenesis. It is a non-neoplastic condition that affects the spleen only; not described in other sites except one case reported in adrenal gland. Epidemiologically it has slight female predilection.

Effects of channelization on macroinvertebrate assemblages in a small stream: The case of Awetu in Jimma City, Ethiopia.

Freshwater ecosystems are increasingly modified worldwide by anthropogenic activities. Land use change is one of the leading factors responsible for stream ecosystem degradation. Physical habitat disturbance due to channelization is among the factors responsible for the loss of biodiversity and degradation of river water quality worldwide.

Predictors of mortality at 3 months in patients with skull base tumor resections in a low-income setting.

Objective: Globally, skull base tumors are among the most challenging tumors to treat and are known for their significant morbidity and mortality. Hence, this study aimed to identify robust associated factors that contribute to mortality of patients following surgical resection for a variety of skull base tumors at the 3-month follow-up period. This in turn helps devise an evidence-based meticulous treatment strategy and baseline input for quality improvement work.

Knowledge, attitude, and practice of healthcare workers towards healthcare- associated infections in Jimma University Medical Center, southwestern Ethiopia: using structural equation model.

Background: Healthcare-associated infections (HCAIs) are a common challenge faced in healthcare facilities, particularly in low- and middle-income countries (LMICs). Evaluating the level of knowledge, attitude, and practice (KAP) among healthcare personnel regarding HCAI prevention and identifying the relevant factors is important for handling and controlling these infections. Therefore, this study aimed to assess the direct and indirect effects of knowledge, attitude, and practices of healthcare workers (HCW) towards HCAIs prevention in Jimma University Medical Center (JUMC).

Leveraging machine learning models for anemia severity detection among pregnant women following ANC: Ethiopian context.

Background: Anemia during pregnancy is a significant public health concern, particularly in resource-limited settings. Machine learning (ML) offers promising avenues for improved anemia detection and management. This study investigates the potential of ML models in predicting anemia severity among pregnant women attending Antenatal Care (ANC) visits in Ethiopia.

Association between birth length, linear growth velocities, and primary school achievement at age 10 years: evidence from the Ethiopian iABC birth cohort.

Background: Childhood is a period marked by dynamic growth. Evidence of the association between childhood linear growth and school achievement comes mostly from cross-sectional data. We assessed associations between birth length, childhood linear growth velocities, and stunting with school achievement.

Electronic health literacy and its associated factors among university students using social network sites (SNSs) in a resource-limited setting, 2022: cross-sectional study.

Background: E-health literacy is defined as an individual's ability to look for and appraise health information from online electronic sources. In this digital age, e-health literacy is one of the most important determinants of health and health behaviors, particularly among adolescents who often influenced by information from various social network sites (SNSs) in developed countries. However, there is limited evidence regarding eHealth literacy level and its associated factors among jimma university undergraduate students using SNSs in less developed settings.

Placental malaria and adverse pregnancy outcomes in Majang Zone of Gambella Region, Southwest Ethiopia: a histopathological and molecular study.

Background: Placental malaria (PM) is characterized by Plasmodium parasite sequestration in the placenta. It is responsible for various adverse pregnancy outcomes, including maternal anaemia and low birth weight (LBW). This study aimed to assess prevalence and risk factors of PM, and gestational malaria (GM), together with the prevalence of congenital malaria (CM), maternal anaemia, and LBW among parturient women attending delivery ward of Metti Health Centre (Metti HC) in Majang Zone of Gambella Region, Southwest Ethiopia.

Prevalence and pathogen profiles of bacteremia in neonates hospitalized for clinical Sepsis in Ethiopia: a systematic review and meta-analysis.

Background: Bacteremia is prevalent in neonates, largely attributed to factors inherent in the neonatal period. However, the prevalence of proven bacteremia in Ethiopian neonates has not been previously synthesized. Accordingly, this systematic review and meta-analysis aimed to analyze the prevalence of bacteremia and pathogen profiles in neonates hospitalized for clinical sepsis in Ethiopia.

Molecular and clinical insights into extended-spectrum β-lactamase genes of Klebsiella pneumoniae isolated from neonatal sepsis in Ethiopia.

Background: Klebsiella bacterial strains harboring Extended-Spectrum Beta-Lactamase (ESBL) enzymes are the primary culprits behind neonatal sepsis globally. These strains significantly impact clinical outcomes due to their multi-drug resistance patterns in local healthcare settings. In response to this spiraling threat, we studied the prevalence and clinical implications of ESBL-encoding genes in neonates hospitalized with confirmed sepsis.

Estimating the structural and spatial variables of allantoinase enzyme critical for protein adsorption.

Designing enzyme-based sensors necessitates a comprehensive exploration of macromolecular properties. Integrating enzymes with a suitable transducer involves immobilizing them onto a surface, facilitated through adsorption or entrapment techniques. Allantoin, a stable biomarkers metabolite, holds promise for detecting oxidative stress-related complications through its enzyme.

Vaccination card loss and associated factors in Ethiopia: A multilevel analysis using Ethiopia Mini Demographic and Health Survey 2019 data.

Background: The loss of vaccination cards is a momentous public health challenge in the prevention of vaccine-preventable diseases in most developing countries. There is a paucity of studies on the magnitude of vaccination card losses and associated factors in Ethiopia. Therefore, the aim of the current study was to assess the level of vaccination card loss and associated factors in Ethiopia.

Unveiling the role of DHIS2 in enhancing data quality and accessibility in primary healthcare facilities: Evidence from Ethiopia.

Background: The implementation of DHIS2 in healthcare systems has transformed data management practices worldwide. However, its specific impact on data quality, availability, and performance in Primary Health Unit (PHU) facilities in Ethiopia remains underexplored. Therefore, we investigated the contribution of DHIS2 to enhancing data quality, availability, and performance within PHU facilities in Ethiopia.

Rheumatic heart disease burden and determinants in cardiac patients: A follow up care concern in Ethiopia.

Rheumatic heart disease (RHD) is a neglected tropical disease and remains one of the leading causes of cardiovascular-related deaths in Ethiopia. This study aims to assess the burden of RHD and identify its determinants in the country. A hospital-based cross-sectional study was employed from January 5 to April 15, 2023, among cardiac patients attending Jimma Medical Center.

The association between dolutegravir-based antiretrovirals and high blood pressure among adults with HIV in southern Ethiopia: a cross-sectional study.

Background: Dolutegravir (DTG), a novel antiretroviral therapy (ART) for HIV, is increasingly adopted across sub-Saharan Africa. However, its impact on blood pressure in Ethiopia remains unclear, highlighting a need for further studies.

Objective: This study aimed to investigate the association between DTG-based first-line regimens and other covariates of high blood pressure (HBP) among adults living with HIV receiving care at health facilities in Hawassa City, southern Ethiopia.

Forbidden, yet common: Female genital cutting among the Oromo in central Ethiopia.

This article answers the question 'why female genital cutting (FGC) has remained common among the Oromo in central Ethiopia when it is legally forbidden.' Primary data for this article were generated through key informant interviews and focus group discussions, while secondary data were gathered from online and archives in the research site. Our findings indicate that the government tries to use legislative and health approaches in its efforts to terminate FGC.

Management of primary hepatic pregnancy: A case report.

Hepatic pregnancy, an exceedingly rare subtype of abdominal ectopic pregnancy, remains clinically challenging due to its infrequency, diverse presentations, and diagnostic difficulties. We report the clinical course, diagnostic journey and treatment of a woman with a primary hepatic pregnancy. The patient presented with acute pain in the right hypochondrium and vomiting.

In Vitro Antibacterial Activity, Molecular Docking, and ADMET Analysis of Phytochemicals from Roots of .

is widely used in Ethiopia for treating various human ailments, yet its pharmacological properties and chemical composition remain largely unexplored. The chromatographic separation of roots extract afforded five compounds, namely tremulacin (), cochinchiside A (), 5-methoxydurmillone (), catechin-7--α-L-rhamnopyranoside (), and stigmasterol (), confirmed via IR, NMR, and MS spectral data. This is the first report of these compounds from this plant, except for compounds and .

Awareness of Poultry Farmers of Interconnected Health Risks: A Cross-Sectional Study on Mycotoxins, Biosecurity, and Salmonellosis in Jimma, Ethiopia.

Poultry farming in Ethiopia is crucial for food security and income, but it faces significant challenges due to gaps in farmer awareness. A cross-sectional study was conducted using the Biocheck.UGent™ biosecurity scoring system and a questionnaire to evaluate poultry farmers' basic and practical knowledge concerning salmonellosis and mycotoxins.