Association between complete blood cell count-derived inflammatory biomarkers and gallstones prevalence in American adults under 60 years of age.

Background: The trend of gallstones occurring in younger populations has become a noteworthy public health issue. This study aims to investigate the association between complete blood cell count (CBC)-derived inflammatory indicators and gallstones in adults under 60 years of age in the United States.

Methods: This cross-sectional study used data from the National Health and Nutrition Examination Survey (NHANES) from 2017 to 2020.

GBR assisted Onlay bone grafting for the posterior maxillary horizontal ridge augmentation: a case report and literature review.

The posterior mandible is the primary area for occlusal function. However, long-term tooth loss in the posterior mandible often leads to rapid absorption of both buccal and lingual trabecular bone plates and subsequent atrophy of the alveolar ridge. This ultimately results in horizontal bone deficiencies that complicate achieving an optimal three-dimensional placement for dental implants.

Molecular dynamics of chemotactic signalling orchestrates dental pulp stem cell fibrosis during aging.

Aging often triggers dental pulp fibrosis, resulting in clinical repercussions such as increased susceptibility to dental infections, compromised tooth vitality, and reduced responsiveness to dental interventions. Despite its prevalence, the precise molecular mechanisms underlying this condition remains unclear. Leveraging single-cell transcriptome analysis from both our own and publicly available datasets, we identified Ccrl2 macrophages as particularly vulnerable during the early stages of aging.

Highly Crystalline and Flexible Covalent Organic Frameworks: Advancing Efficient Iodine Adsorption.

Flexible covalent organic frameworks (COFs) offer distinct advantages in elasticity and adaptability over rigid COFs, but these benefits often come at the expense of crystallinity due to challenges in polymerization, complicating both synthesis and structural characterization. Current research primarily employs single flexible monomers, which limits the tunability of these frameworks. In this study, we introduce two highly crystalline, flexible COFs, ZCST-102 and ZCST-103, constructed from dual flexible monomers.

Effect of cold atmospheric plasma on common oral pathogenic microorganisms: a narrative review.

Background: The oral microbiota is a diverse and complex community that maintains a delicate balance. When this balance is disturbed, it can lead to acute and chronic infectious diseases such as dental caries and periodontitis, significantly affecting people's quality of life. Developing a new antimicrobial strategy to deal with the increasing microbial variability and resistance is important.

Mung bean-derived carbon dots suppress ferroptosis of Schwann cells the Nrf2/HO-1/GPX4 pathway to promote peripheral nerve repair.

Schwann cells (SCs) can potentially transform into the repair-related cell phenotype after injury, which can promote nerve repair. Ferroptosis occurs in the SCs of injured tissues, causing damage to the SCs and exacerbating nerve injury. Targeting ferroptosis in SCs is a promising therapeutic strategy for effective repair; however, research on ferroptosis in the peripheral nervous system remains limited.

Chemo-Mechanical Due-Biomimetic Approach for Ultra-Stable Adsorption Across Multiple Scenarios.

The unique adhesion capabilities of soft-bodied creatures such as leeches and octopuses have provided considerable inspiration for the development of artificial adhesive materials. However, previous studies have either focused on the design of sucker structures or concentrated on the synthesis of adhesive materials, with the combination of these two aspects not yet having been deeply investigated. In this study, inspired from leech's unique adsorption ability, a biomimetic approach is proposed that combined artificial sucker and mucus, to achieve remarkable adhesion stability on rough surfaces using 5 cm diameter silicone suction cups.

Prolonged screen time is associated with increased severity of tic symptoms in children with tic disorders.

Background: Recent studies have emphasized the association between prolonged screen exposure and neurodevelopmental disorders, though its correlation with tic disorders (TDs) remains ambiguous. We thus conducted this study to investigate the association between screen time (ST) and the severity of tic symptoms in children diagnosed with TDs.

Methods: We conducted a retrospective case-control study with 342 cases of TDs and 270 controls, collecting data from March 2021 to December 2023.

[Clinical characteristics and prognosis of type 1 infratentorial superficial siderosis].

A total of 7 patients with type 1 infratentorial superficial siderosis(iSS-1)in Memory Clinic at Huashan Hospital, Fudan University from March 2019 to March 2023 were respectively collected to analyze the clinical characteristics and treatment, and followed up for 12 months. There were 7 patients, 2 males and 5 females, aged 56 (49-60) years. The 4 patients who underwent cognitive assessment had varying degree of cognitive impairment, with 2 patients exhibiting severe executive function impairment.

The Application of Voice Biomarkers in Frailty: A Scoping Review.

Background: With an increasing prevalence of frailty among older adults, effective classification and management strategies for frailty have become imperative. Voice biomarkers, offering insights into the overall health status of older adults, hold promise for enhancing the management of this multifaceted geriatric syndrome.

Objectives: This scoping review aims to consolidate existing knowledge regarding the relationship between frailty and voice biomarkers.

Efficient Spermidine Production Using a Multi-Enzyme Cascade System Utilizing Methionine Adenosyltransferase from Lactobacillus fermentum with Reduced Product Inhibition and Acidic pH Preference.

Methionine adenosyltransferases (MATs; EC 2.5.1.

HDAC3 and Snail2 complex promotes melanoma metastasis by epigenetic repression of IGFBP3.

The treatment of metastatic melanoma has long posed a complex challenge within clinical practice. Previous studies have found that EMT transcription factors are essential in the development of various cancers through their induction of EMT. Here, we demonstrate that Snail2 expression is dramatically increased in melanoma and is associated with an adverse prognosis.

Long-term exposure to fine particulate matter components with obesity in children and adolescents in China: The age-sex disparities and key effect modifiers.

Long-term fine particulate matter (PM) exposure was associated with childhood obesity. However, the key PM components and whether PM effect may vary by obesity type, growth stage, sex, and individual/family characteristics have yet been examined. In this study, we investigated 213,907 Chinese children and adolescents aged 3-18 years in 2017-2019.

TiCT/Au NPs/PPy ternary heterostructure-based intra-capacitive self-powered sensor for DEHP detection.

Phthalate esters, particularly di(2-ethylhexyl) phthalate (DEHP), are widely used plasticizers found in various consumer products, posing significant environmental and health risks due to their endocrine-disrupting effects. In this study, a novel enzyme-free intra-capacitive biofuel cell self-powered sensor (ICBFC-SPS) was developed. The ICBFC-SPS integrated a ternary heterostructure-based capacitive anode and a cathode with a sensing interface into a single-chamber electrolytic cell.

[Expert consensus on visualized tele-round and quality control management based on the improvement of clinical practice ability].

Turning to critical illness is a common stage of various diseases and injuries before death. Patients usually have complex health conditions, while the treatment process involves a wide range of content, along with high requirements for doctor's professionalism and multi-specialty teamwork, as well as a great demand for time-sensitive treatments. However, this is not matched with critical care professionals and the current state of medical care in China.

Research of mesoporous silica loaded lignin to enhance the anti-corrosion and anti-weathering performance of epoxy surface.

A new type of filler was added to epoxy resin to prepare a composite coating with excellent corrosion and weathering resistance. The simple synthesis process and nonpolluting raw materials of this filler contribute to the development of green chemistry. Specifically, lignin was encapsulated in mesoporous silica, the synergistic effect between the two resulted in the formation of lignin/mesoporous silica composite particles (MSN-L) with excellent ultraviolet (UV) resistance.

Associations of breakfast habits and breakfast quality with depression: A cross-sectional study based on NHANE 2007-2018.

Background: Breakfast, often considered the most important meal of the day, affects both physical and mental health. While most studies focused on the effects of skipping breakfast on depression, few explored the roles of breakfast quality and breakfast time. The study aimed to investigate the association of breakfast habits and breakfast quality with depression.

Anti-osteosarcoma activity of Corynoline via Src/JNK signaling-mediated cell cycle arrest and mitochondrial apoptosis.

Corynoline (COR) is an isoquinoline alkaloid derived from the traditional Chinese medicine Corydalis bungeana Turcz, known for its analgesic, antibacterial, neuroprotective, and osteoporosis-alleviating properties. However, its potential molecular effects against osteosarcoma (OS) remain unclear, warranting further investigation. This study demonstrated that COR inhibits OS cell proliferation and promotes apoptosis in a dose-dependent manner.

Two algorithms for improving model-based diagnosis using multiple observations and deep learning.

Model-based diagnosis (MBD) is a critical problem in artificial intelligence. Recent advancements have made it possible to address this challenge using methods like deep learning. However, current approaches that use deep learning for MBD often struggle with accuracy and computation time due to the limited diagnostic information provided by a single observation.

A rare case of recurrent calcifying epithelial odontogenic tumor in an adolescent patient: Case report and review of literature.

Calcifying epithelial odontogenic tumor (CEOT) is a rare benign odontogenic epithelial tumor characterized by the presence of amyloid material within the tumor that can undergo calcification. CEOT affects individuals across a broad age range, typically between 20 and 60 years, with an average onset age of 40 years. However, it is extremely rare in children and adolescents.

Protocol for extraction of gut interstitial fluid in mice with two-front nutrient supply.

The intestine features a two-front nutrient supply environment, comprising an enteral side enriched with microbial and dietary metabolites and a serosal side supplied by systemic nutrients, collectively supporting intestinal and systemic homeostasis, but there is currently no optimal approach for extracting and assessing the local intestinal microenvironment. Here, we present a protocol for constructing a nutrient supply model in mice and extracting gut interstitial fluid (GIF) via centrifugation. This model and the extracted GIF are suitable for downstream analyses.

Correction: Zhang et al. Interactions of Self-Assembled Polysaccharide Nanoparticles with Bovine Serum Albumin and Biodistribution of Its Docetaxel-Loaded Nanoparticles. 2019, , 43.

In the original publication [...

Ground-Target Recognition Method Based on Transfer Learning.

A moving ground-target recognition system can monitor suspicious activities of pedestrians and vehicles in key areas. Currently, most target recognition systems are based on devices such as fiber optics, radar, and vibration sensors. A system based on vibration sensors has the advantages of small size, low power consumption, strong concealment, easy installation, and low power consumption.

An Airborne Gravity Gradient Compensation Method Based on Convolutional and Long Short-Term Memory Neural Networks.

As gravity exploration technology advances, gravity gradient measurement is becoming an increasingly important method for gravity detection. Airborne gravity gradient measurement is widely used in fields such as resource exploration, mineral detection, and oil and gas exploration. However, the motion and attitude changes of the aircraft can significantly affect the measurement results.