Colorimetric sensing of glucose and GSH using core-shell Cu/Au nanoparticles with peroxidase mimicking activity.

The catalytic properties of bimetallic nanoparticles have been widely studied by researchers in many fields. In this paper, core-shell Cu/Au nanoparticles (Cu/Au NPs) were synthesized by a simple and mild one-pot method, and their peroxidase activity was proved by catalyzing the oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) with color change to blue. The change of solution color and absorbance strongly depends on the concentration of HO, so it can be used for direct detection of HO and indirect detection of glucose.