Comparison of the Efficacy and Safety of Direct Oral Anticoagulants and Warfarin in Cirrhotic Patients: A Systematic Review and Meta-Analysis.

Objective: Currently, there is limited evidence regarding the use of direct oral anticoagulants (DOACs) for patients with liver cirrhosis (LC). We performed a meta-analysis to compare the efficacy and safety of DOACs versus warfarin in this population.

Methods: We searched PubMed, Cochrane Library, Web of Science, Embase and Scopus databases from inception to August 2024.

Too much social media? Unveiling the effects of determinants in social media fatigue.

Introduction: With the boom in social media, many people spend a lot of time on these platforms. Among them, some developed negative emotions, such as fatigue, depression, or disinterest in communicating, and used social media temporarily or permanently. Therefore, this study aims to explore the antecedents of social media fatigue, including social media helpfulness, social media self-efficacy, online subjective well-being, social comparison, compulsive social media use, privacy concerns, fear of missing out, and information overload, and to further discuss the determinants of social media fatigue on social anxiety and lurking.

Investigations on the EPR g factors and local structures for the orthorhombic and tetragonal Cu centers in Pb[ZrTi]O.

The defect models of the orthorhombical and tetragonal Cu centers in Pb[ZrTi]O are attributed to Cu ions occupying the sixfold coordinated octahedral Ti site with and without charge compensation, respectively. The electron paramagnetic resonance (EPR) g factors g (i = x, y, z) of the Cu centers in Pb[ZrTi]O are theoretically studied by using the perturbation formulas of a 3d ion under orthorhombically and tetragonally elongated octahedra. Based on the calculation, the impurity off-center displacements are about 0.

Education disrupts the intergenerational transmission of health disadvantage across three generations in China.

This article utilizes survey data from the China Family Panel Studies (CFPS) to examine whether grandparents' health disadvantage have both direct and indirect effects on the health disadvantage of their grandchildren, and whether the completion of compulsory education by parents disrupts these intergenerational transmissions in China. The findings suggest that grandparents' health disadvantage significantly increases the probability of grandchildren's health disadvantage with and without controlling parental health disadvantage and other characteristics. Moreover, the study identifies a disruptive influence of parental education on this transmission process.

Prevalence of coccidia in lagomorphs in China between 1981 and 2023: A systematic review and meta-analysis.

Lagomorpha coccidiosis, caused by coccidia, is a prevalent disease affecting rabbits, hares and pikas. This meta-analysis aimed to estimate the pooled prevalence of coccidia infection in lagomorphs and identify potential risk factors. A systematic search of six databases yielded 102 studies published between 1981 and 2023.

GSB: GNGS and SAG-BiGRU network for malware dynamic detection.

With the rapid development of the Internet, the continuous increase of malware and its variants have brought greatly challenges for cyber security. Due to the imbalance of the data distribution, the research on malware detection focuses on the accuracy of the whole data sample, while ignoring the detection rate of the minority categories' malware. In the dataset sample, the normal data samples account for the majority, while the attacks' malware accounts for the minority.

Practical effect of different teaching modes in teaching gastrointestinal surgery nursing.

Background: With the continuous development and progress of medical technology, the position of surgical nursing in the field of clinical medicine is becoming increasingly prominent. As an important branch of the surgical field, the nursing requirements and difficulty of gastrointestinal surgery are also increasing. In order to improve the teaching quality of nursing care in gastrointestinal surgery, many educators and researchers are actively exploring new teaching methods.

An EEG monitoring method based on compressed sensing for fatigue driving.

In order to reduce the amount of EEG collected by the fatigue driving monitoring system, this paper proposes a new EEG monitoring method based on compressed sensing. According to the driver's driving duration, the new proposed method adopts different sampling rate to compressive sample the EEG of the driver in different driving stages, and then realizes the accurate reconstruction of the compressed EEG data in the computer of vehicle. The experiment verifies effectiveness of the proposed method by collecting EEG signals from multiple subjects during simulated driving.

First-principle study on the geometric and electronic structure of Mg-doped LiNiO for Li-ion batteries.

Context: Ni-rich layered oxides have been widely studied as cathodes because of their high energy density. However, the gradual structural transformation during the cycle will lead to the capacity degradation and potential decay of the cathode materials. In this paper, first-principle calculations were used to investigate the formation energy, and geometric and electronic structure of Mg-doped LiNiO cathode for Li-ion batteries.

Theoretical studies on the local structure and spin Hamiltonian parameters for Cu ions in LiTaO crystal.

The local structure and spin Hamiltonian parameters (SHPs) g factors (g , g , g ) and the hyperfine structure constants (A , A , A ) for Cu doped in the LiTaO crystal are theoretically investigated by the perturbation formulas for a 3d ion under rhombically elongated octahedral based on the cluster approach. The impurity Cu was assumed to occupy the host trigonally-distorted octahedral Li site and experience the Jahn-Teller (JT) distortion from the host trigonal octahedral [TaO ] to the impurity rhombically elongated octahedral [CuO ] . Based on the calculations, the impurity-ligand bond lengths parallel and perpendicular to the C -axis are found to be R (≈ 2.

Crystalline NiP/amorphous CePO core/shell heterostructure arrays for highly-efficient electrocatalytic overall water splitting.

Exploring low-cost and highly efficient bifunctional electrocatalysts for overall water splitting has become a research focus recently. Crystalline/amorphous core/shell heterostructures have great potential for applications in the field of electrocatalytic overall water splitting. However, related research is still challenging.

Geniposide promotes wound healing of skin ulcers in diabetic rats through PI3K/Akt pathway.

Continuously hyperglycation-induced lesion and poor blood flow contributed to the wound incurable and susceptible to infection. About fifteen percent of people with diabetes would develop ulcers during their lifetime, especially on the feet, which could lead to severe tissue destruction and eventual amputation. Various strategies were limited to accelerate wound healing in diabetic patients for high cost and unsatisfied effects.

[Current Status of and Barriers to the Implementation of Enhanced Recovery After Surgery in 77 Tertiary Hospitals].

Objective: To investigate the status of and obstacles to the implementation of enhanced recovery after surgery (ERAS) in tertiary-care general hospitals in China.

Methods: Questionnaire on the Current Status of and Barriers to the Implementation of ERAS in Tertiary-Care Hospitals, a self-developed questionnaire, was used to conduct a survey of 77 tertiary hospitals from 21 provinces across China between May 2022 and June 2022. The participating hospitals were selected by convenience sampling.

Facet-specific NiCoO/FeO p-n heterojunction with promising triethylamine sensing properties.

Semiconductor gas sensing materials with specific crystal facets exposure have attracted researchers' attention recently. However, related research mainly focuses on single metal oxide semiconductor. The research on crystal facets designing of semiconductor p-n heterojunction is still highly challenging.

MWCNTs dispersion adopting GA and its application towards copper tailings-based cementitious materials.

Hydrophobic carbon nanotubes are hardly to disperse in water and prone to agglomerate when poured with Copper Tailing-Based Cementitious Material (CTCM). Multi-walled carbon nanotubes (MWCNTs) + Arabic Gum (GA) dispersions were prepared by a novel method of synergistic optimization of concentration, controlling low-frequency ultrasonic time and setting the ambient temperature with non-toxic anionic surfactant GA as surfactant. The results of UV-Vis spectroscopy showed that the high stability MWCNTs + GA dispersion with low aggregation area (< 1.

The impact of carbon emission trading policy on energy efficiency-evidence from China.

Energy efficiency (EE) plays an important role in achieving the dual-carbon goal, and improving EE is thus indispensable. This paper evaluates the impact of carbon emission trading policy (CETP) on EE based on a difference-in-difference (DID) method, using 16-year data of 30 provinces and cities from 2005 to 2020. Conclusions are as follows: (1) CETP significantly promotes EE, and this conclusion still appears valid after robustness tests.

How military spending, economic growth, and renewable energy impacts ecological footprints in Next Eleven nations.

The objective of this study is to investigate the association between military spending and environmental sustainability within the N-11 countries. There exists a strong correlation between sustainable economic expansion and energy consumption, which in turn results in the generation of elevated levels of carbon emissions. Moreover, it is plausible that a correlation exists between military spending and the degradation of the environment.

Anti-cerebral ischemic neuronal injury mechanism of Zhenlong Xingnao capsules: role of the Notch/NF-κB signaling pathway.

Objective: To investigate the anti-cerebral ischemia-reperfusion injury (CIRI) effect and mechanism of Zhenlong Xingnao capsules based on Notch/NF-κB signaling pathway.

Methods: The rat model of middle cerebral artery occlusion (MCAO) was established using the Longa suture occlusion method, and 70 rats were divided into sham-operated, model, low dose Zhenlong Xingnao capsule group (125 mg/kg Zhenlong Xingnao capsule solution) and high dose Zhenlong Xingnao capsule group (250 mg/kg Zhenlong Xingnao capsule solution), low dose Zhenlong Xingnao capsule + neurogenic site notch homologous protein 1 (Notch1) antibody (Jagged1 group, 125 mg/kg capsule solution + 25 mg/kg Jagged1 solution), high dose Zhenlong Xingnao capsule + Jagged1 group (250 mg/kg capsule solution + 25 mg/kg Jagged1 solution), and Jagged1 group (25 mg/kg Jagged1 solution). The learning and memory abilities (behavioral score, spontaneous movement, and rotarod test), neurological function score, inflammatory factors and oxidative stress levels [interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), malondialdehyde (MDA), glutathione peroxidase (GSH-Px), superoxide dismutase (SOD)] in hippocampal tissue, and Bcl-2, Bax, and Caspase-3 mRNA levels were measured by reverse transcription quantitative polymerase chain reaction, and Notch1/NF-κB signaling pathway-related protein expression was assessed by Western blot.

Survey and analysis of the current status of research in the field of outdoor navigation for the blind.

Purpose: In this article, we comprehensively review the current situation and research on technology related to outdoor travel for blind and visually impaired people (BVIP), given the diverse types and incomplete functionality of navigation aids for the blind. This aims to provide a reference for related research in the fields of outdoor travel for BVIP and blind navigation.

Materials And Methods: We compiled articles related to blind navigation, of which a total of 227 of them are included in the search criteria.

In-situ construction of direct Z-scheme NiO/BiMoO heterostructure arrays with enhanced room temperature ether sensing properties under visible light irradiation.

Light irradiation has emerged as a promising strategy to promote room temperature sensing of resistive-type semiconductor gas sensors recently. However, high recombination rate of photo-generated carriers and poor visible light response of conventional semiconductor sensing materials have greatly limited the further performance improvement. It is urgent to develop gas sensing materials with high photo-generated carrier separation efficiency and excellent visible light response.

Attitude of undergraduate nursing interns in regard to death and the influencing factors.

Object: To explore the influencing factors of attitudes about death among undergraduate nursing interns.

Methods: The study subjects were selected from the full-time fourth year undergraduate nursing interns in Jiangxi University of Technology from January to March 2021 by convenience sampling method. The general information questionnaire was designed by our hospital, and attitude towards death referred to the Chinese version of Death Attitude Depiction Scale (Revised) (DAP-R).

Application of SDN Network Traffic Prediction Based on Speech Recognition in Educational Information Optimization Platform.

This paper constructs a SDN network traffic prediction model based on speech recognition and applies it to the educational information optimization platform. By analyzing the influencing factors of SDN network equipment, communication links, and network traffic, this paper constructs the initial index set of SDN network traffic situation. In the data plane of SDN, the queue management algorithm is used to control the flow.

LncRNA MEG3 inhibits renal fibrinoid necrosis of diabetic nephropathy via the MEG3/miR-21/ORAI1 axis.

Introduction: Diabetic nephropathy (DN) is one of the most common and lethal diabetic complications worldwide and is associated with a high risk of mortality. However, the exact mechanism behind its development is unknown. The mesangial cells (MCs) and non-coding RNAs are critical for DN, but it is unknown whether a MEG3/miR-21/ORAI1 regulatory axis exists in MCs.