2 results match your criteria: "Jiangxi Provincial Institute of Parasitic Diseases Control and Prevention[Affiliation]"
[Study on immune status of patients with schistosomiasis japonica in Poyang Lake region II characterization of cellular immune in schistosomiasis patients].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
December 2012
Jiangxi Provincial Institute of Parasitic Diseases Control and Prevention, Nanchang 330046, China.
Article Synopsis
- The study aimed to analyze the immune response of patients with schistosomiasis japonica in a low endemic area, focusing on specific immune cell types and cytokine levels.
- Patients classified as positive for schistosomiasis showed significantly higher levels of CD4+CD25+T regulatory cells compared to negative controls, indicating an immune response shift.
- Post-treatment results revealed increased levels of IFN-gamma (an immune-activating cytokine) and decreased levels of IL-10 (an immune-suppressing cytokine), suggesting that the presence of CD4+CD25+Tregs may dampen cellular immunity following infection.
[Study on immune status of patients with schistosomiasis japonica in Poyang Lake region I characterization of antigen-specific antibody isotype responses to Schistosoma japonicum].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
October 2012
Jiangxi Provincial Institute of Parasitic Diseases Control and Prevention, Nanchang 330046, China.
Article Synopsis
- The study aimed to analyze the antibody responses to Schistosoma japonicum in patients from the Poyang Lake region, focusing on both soluble egg antigen (SEA) and adult worm antigen (AWA).
- It found that patients who tested positive for eggs had significantly higher levels of specific antibody isotypes compared to those who tested negative and a control group from a non-endemic area.
- Post-treatment, most antibody levels decreased significantly within twelve months, indicating a reduction in immune response over time.