14 results match your criteria: "Jiangsu Subei People's Hospital[Affiliation]"

Objective: This study aimed to analyse the effect of pelvic floor function exercises based on the enhanced recovery after surgery (ERAS) concept on lower urinary tract symptoms after radical hysterectomy for cervical cancer.

Methods: The retrospective study was conducted using clinical data of patients admitted to our hospital from January 2021 to December 2022 and underwent radical hysterectomy for cervical cancer. In accordance with the nursing method, the patients were divided into the routine group (conventional care) and the ERAS pelvic floor function exercise group, for which ERAS concept-based pelvic floor function exercises were carried out on the basis of the former group.

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Objective: Mendelian randomization (MR) was used to explore the causal relationship between diabetes (type 1 and type 2) and prostate cancer (PCa) in East Asian population.

Methods: Mendelian randomization is a causal inference method based on genetic variation, which uses the influence of randomly assigned genotypes in nature on phenotype to infer the impact of biological factors on diseases. This study used genetic variation genes related to inflammatory biomarkers as instrumental variables to improve inference, and patient data was obtained from the GWAS database's aggregated association results.

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The use of immune checkpoint inhibitors (ICIs) has shown remarkable efficacy in the treatment of various malignancies, significantly reshaping cancer treatment. However, as a result of the widespread use of ICIs, several immune-related adverse events (iRAEs) have emerged, some of which can be rare and potentially fatal. In this paper, we reported the earliest case of Sintilimab used in the treatment of esophageal cancer with severe inflammatory myopathy (involving the cardiac, respiratory, and skeletal muscles)in China.

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Background: Plasma S100A1 protein is a novel inflammatory biomarker associated with acute myocardial infarction and neurodegenerative disease's pathophysiological mechanisms. This study aimed to determine the levels of this protein in patients with acute ischemic stroke early in the disease progression and to investigate its role in the pathogenesis of acute ischemic stroke.

Methods: A total of 192 participants from hospital stroke centers were collected for the study.

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The predictive value of galectin-1 and vascular mimicry in the prognostic evaluation of patients with rectal cancer.

Transl Cancer Res

March 2021

Department of Gastrointestinal Surgery, Subei Hospital Affiliated to Yangzhou University (Jiangsu Subei People's Hospital), Yangzhou University-Yangzhou General Surgery Institute, Yangzhou, China.

Background: This study aims to investigate the expression of galectin-1 and vascular mimicry (VM) in rectal cancer tissues, and to assess their predictive value in the prognostic evaluation of patients with rectal cancer.

Methods: Immunohistochemistry (IHC) and CD34-periodic acid solution (PAS) double staining were used to detect galectin-1 expression and the formation of VM in rectal cancer tissues from 94 patients with stage I-III rectal cancer and their corresponding paracancerous tissues. We also analyzed the relationship between the expression of galectin-1, VM, various clinicopathological parameters, and the prognosis of rectal cancer patients, as well as their influence on the overall survival (OS) of rectal cancer patients.

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Whole-brain radiotherapy (WBRT) is the mainstay of therapy in treating cancer patients with brain metastases, but unfortunately, it might also lead to decline in neurocognitive function. This study aims to investigate the preservation of long-term neurocognitive function in patients after hippocampal avoidance whole-brain radiotherapy (HA-WBRT). Retrospectively, 47 patients diagnosed with brain metastases of non-small cell lung cancer (NSCLC) between 2015-01-01 and 2017-12-31 at the Department of Oncology, XXX Hospital were selected and divided into 2 groups.

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Background: Red blood cell distribution width to platelet ratio (RPR), Monocyte to high-density lipoprotein ratio (MHR), and Neutrophil to lymphocyte ratio (NLR) are novel inflammatory biomarkers in laboratory tests, which are associated with clinical outcomes in malignancy, cardiovascular and cerebrovascular diseases. This study aimed to determine their predictive value for the prognosis of acute ischemic stroke after mechanical thrombectomy (MT).

Methods: A total of 286 patients with acute ischemic stroke (AIS) admitted to a tertiary stroke center in China between January 2018 and February 2020 were treated by MT.

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[Advances in Preparation and Evaluation of Non-vascular Drug-eluting Stents].

Zhongguo Yi Liao Qi Xie Za Zhi

February 2021

Jiangsu Subei People's Hospital Affiliated to Medical School, Yangzhou University, Yangzhou, 225001.

In recent years, the application of stent intervention in the treatment of non-vascular stenosis caused by benign and malignant factors has been widely concerned by researchers at home and abroad. The high incidence of malignant tumor diseases, further promotes the development of stent intervention. The conventional bare stents are prone to irritate luminal mucosa and produce restenosis and other complications.

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To systematically evaluate the safety and efficacy of dexmedetomidine combined with ketamine during dressing changes in burn patients using meta-analysis. Foreign language databases including PubMed, Cochrane Central, Embase, and Web of Science were searched with the terms of " burns, dexmedetomidine, ketamine, and dressing" , and Chinese databases including Chinese Journal Full-Text Database, Wanfang Data, and China Academic Journal Network Publishing Database were searched with the terms in Chinese version of ",,,,," to retrieve the publicly published randomized controlled trials on the application of dexmedetomidine combined with ketamine for sedation and analgesia during dressing changes in burn patients from the establishment of each database to March 2019. The outcome indexes included systolic blood pressure at 5 minutes after administration, arousal restlessness score, ketamine dosage, dressing change time, body movement/recovery time, pain score, Ramsay sedation scores at 10 minutes after the start of dressing change and 1 hour after dressing change, physician satisfaction score, neuropsychological symptoms, nausea and vomiting times, nausea and vomiting score.

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[Analysis of the recurrence related factors of sinonasal inverted papilloma].

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi

December 2017

Department of Otorhinolaryngology Head and Neck Surgery, Jiangsu Subei People's Hospital.

To evaluate the influence risk factors of recurrence and the methods for reducing recurrence of sinonasal inverted papilloma (SNIP). Clinical data of 34 patients with SNIP were analyzed retrospectively. All of them were unilateral onset.

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Circular RNA VMA21 protects against intervertebral disc degeneration through targeting miR-200c and X linked inhibitor-of-apoptosis protein.

Ann Rheum Dis

May 2018

Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Objectives: Circular RNAs (circRNAs) have been proven to function as competing endogenous RNAs to interact with microRNAs (miRNAs) and influence the expression of miRNA target mRNAs. In this study, we investigated whether circRNAs could act as competing endogenous RNAs to regulate the pathological process of intervertebral disc degeneration (IVDD).

Methods: The role and mechanism of a circRNA, circVMA21, in IVDD were explored in nucleus pulposus (NP) cells and degenerative NP tissues from patients and rat models.

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Objective: This paper aims to compare dosimetric differences based on three types of radiotherapy plans for postoperative left breast cancer. In particular, based on a clinical dosimetric study, the three-dimensional conformal radiotherapy (3D-CRT), intensity- modulated radiation therapy (IMRT) and VMAT plans were implemented on 15 cases of postoperative patients with left breast cancer with prescription doses of 5000cGy.

Methods And Results: Dose volume histogram (DVH) was used to analyze each evaluation index of clinical target volume (CTV) and organs at risk (OARs).

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[Functions of inflammatory factor in non-tumor deep venous thrombosis of lower extremity].

Zhonghua Yi Xue Za Zhi

March 2015

Department of Clinical Medicine, Jiangsu Subei People's Hospital, Yangzhou Institute of Hematology Laboratory, Yangzhou 225001, China. Email:

Objective: To explore the functions of inflammatory cytokine, tissue factor (TF) and cancer procoagulant (CP) in non-tumor deep venous thrombosis (NT-DVT).

Methods: A total of 17 NT-DVT patients (5 males and 12 females) were selected for NT-DVT group while 20 voluntary (10 males and 10 females) blood donors for control group from May 2012 to March 2013. The levels of inflammatory cytokines interleukin 1β (IL-1 β), IL-18, tumor necrosis factor alpha (TNF-α), TF and CP were tested by enzyme-linked immunosorbent assay (ELISA) before and after treatment.

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Aims: The aims of this study were to compare ventricular repolarisation parameters in patients who underwent cardiac resynchronisation therapy (CRT) at Sun Yat-sen University Memorial Hospital under different ventricular pacing modes and to understand effects of epicardial pacing on ventricular repolarisation.

Methods: The study included 55 patients who underwent CRT. During follow-up outpatient visits three months after CRT implantation, the CRT devices were programmed to deliver no pacing (with the exception of patients with third-degree atrioventricular block), biventricular pacing (BivP), right ventricular endocardial pacing (RV-EndoP), and left ventricular epicardial pacing (LV-EpiP).

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