69 results match your criteria: "Jiangsu Institute of Marine Resources Development[Affiliation]"

Natural flavonoids have been shown to have many pharmacological activities. Efficient and continuous enrichment of total flavonoids with high content and low mobile phase usage from complex natural products is greatly needed at the moment. In this study, a new continuous chromatography system (CCS) with 6 zones and the 18-column dynamic tandem connection technique was developed and used to enrich total flavonoids from Epimedium koreanum Nakai (EKN).

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How Does Mangrove Restoration or Reforestation Change Trace Metal Pollution in Mangrove Ecosystems? A Review of Current Knowledge.

Toxics

November 2024

Key Laboratory of the Ministry of Education for Earth Surface Processes, College of Urban & Environmental Sciences, Peking University, Beijing 100089, China.

In recent years, mangrove restoration has gained significant attention due to its carbon storage capacity, role as a pollution sink, and ecological and economic benefits. Moreover, the United Nations Sustainable Development Goals' strategies include mangrove restoration. This review investigates the status of mangrove restoration research and the influence of restoration on trace metal accumulation, speciation, and associated risks in mangrove sediments.

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Characterization of a salt-tolerated exo-fructanase from Microbacterium sp. XL1 and its application for high fructose syrup preparation from inulin.

Int J Biol Macromol

December 2024

Jiangsu Key Laboratory of Marine Bioresources and Environment, Jiangsu Ocean University, 59 Cangwu Road, Haizhou, Lianyungang 222005, China; Co-Innovation Center of Jiangsu Marine Bio-industry Technology, Jiangsu Ocean University, 59 Cangwu Road, Lianyungang 222005, China; Jiangsu Institute of Marine Resources Development, 59 Cangwu Road, Haizhou, Lianyungang 222005, China.

Article Synopsis
  • Exo-fructanase enzymes break down fructans like levan and inulin, producing fructose, and this study focuses on a newly identified enzyme, Mle3A, from Microbacterium sp. XL1.
  • Mle3A has a unique structure with several functional domains and shows optimal activity at temperatures between 50-55 °C and a pH of 5.5, effectively hydrolyzing various sugars including inulin.
  • The enzyme's activity is significantly boosted by certain metal ions, particularly manganese, and it can efficiently convert inulin into high fructose syrup, making it a promising tool for producing valuable chemicals from inulin biomass.
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Design, synthesis and antitumor activity of novel 4-oxobutanamide derivatives.

Bioorg Med Chem Lett

November 2024

School of Pharmacy, Jiangsu Key Laboratory of Marine Bioresources and Environment, Jiangsu Ocean University, Lianyungang 222005, China. Electronic address:

To find highly effective and low-toxicity antitumor drugs to overcome the challenge of cancer, we designed and synthesized a series of novel 4-oxobutanamide derivatives using the principle of molecular hybridization and tested the antiproliferative ability of the title compounds against human cervical carcinoma cells (HeLa), human breast carcinoma cells (MDA-MB-231) and human kidney carcinoma cells (A498). Among them, N-(4-methoxybenzyl)-N-(4-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl) succinimide DN4 (IC = 1.94 µM) showed the best proliferation activity on A498, superior to the positive control paclitaxel (IC = 8.

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Optimizing microbial electrolysis cell performance: strategies to mitigate electron mediator degradation on membranes.

Biotechnol Lett

December 2024

College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, 30 Puzhu South Road, Nanjing, 211816, China.

Article Synopsis
  • - This study investigates the role of neutral red (NR) as an electron mediator during the electrosynthesis of succinic acid by Actinobacillus succinogenes, emphasizing its integration into bacterial cell membranes for efficiency in microbial electrochemical cells (MECs).
  • - Findings show that while NR is quickly absorbed during bacterial growth, adding more NR does not significantly boost acid production, and any loss of membrane-bound NR is not supplemented by NR in the fermentation liquid.
  • - The research highlights the importance of controlling electro-potential to reduce NR degradation, which is crucial for maintaining MEC functionality and efficiency in long-term electrosynthesis processes.
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Benzophenone-4 inhibition in marine diatoms: Physiological and molecular perspectives.

Ecotoxicol Environ Saf

October 2024

Jiangsu Province Engineering Research Center for Marine Bioresources Sustainable Utilization, College of Oceanography, Hohai University, Nanjing 210098, China. Electronic address:

Benzophenone-4 (BP-4), a widely utilized organic ultraviolet (UV) filter, is recognized as a pseudo-persistent contaminant in aquatic environments. To elucidate the effects and mechanisms of BP-4 on marine diatoms, an investigation was conducted on the growth rate, photosynthetic pigment content, photosynthetic parameters, antioxidant enzyme activity, malondialdehyde (MDA) levels, cellular structure, and transcriptome profile of the model species, Phaeodactylum tricornutum. The results showed a pronounced inhibition of algal growth upon exposure to BP-4, with a 144 h-EC value of 201 mg·L.

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causes substantial economic losses in the aquaculture industry. With the rise of multidrug-resistant strains, phages present a promising solution. Here, a novel lytic phage, vB_ValC_RH2G (RH2G), that efficiently infects the pathogenic strain ATCC 17749, was isolated from mixed wastewater from an aquatic market in Xiamen, China.

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The impact of organic carbon mineralization on pollution and toxicity of toxic metal in sediments: Yellow Sea and East China Sea study.

Environ Res

December 2024

CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Shandong Key Laboratory of Coastal Environmental Processes, Research Center for Coastal Environment Engineering Technology of Shandong Province, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, 264003, China. Electronic address:

Organic carbon mineralization is the main driving force of metal migration and transformation in sediments, greatly influencing the distribution, pollution degree, and toxicity of toxic metals. However, relevant research on this subject is still limited. In this study, the concentration of toxic metals (Cr, Cd, Cu, Pb, Zn, Co, Fe, Mn, Ni, As) in the solid and liquid phase (porewater) of sediments were measured, toxic metal pollution degree and toxicity of the Yellow Sea (YS) and the East China Sea (ECS) were assessed.

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Excess fluoride in aqueous solutions can significantly affect dental and bone health. This study used two methods to prepare hydroxyapatite to remove fluoride ions from water. The experiments showed that the adsorption capacity and removal rate of hydroxyapatite (Xq-HAP) prepared by the novel method were higher than for the hydroxyapatite (Yt-HAP) prepared by the conventional method.

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Isolation and Characterization of a Novel Vibrio Phage vB_ValA_R15Z.

Curr Microbiol

July 2024

Centre for Regional Oceans, Department of Ocean Science and Technology, Faculty of Science and Technology, University of Macau, Macau, 999078, China.

Vibrio phages have emerged as a potential alternative to antibiotic therapy for treating Vibrio infections. In this study, a lytic Vibrio phage, vB_ValA_R15Z against Vibrio alginolyticus ATCC 17749, was isolated from an aquatic water sample collected in Xiamen, China. The phage had an icosahedral head (diameter 69 ± 2 nm) and a short, non-contractile tail measuring 16 ± 2 nm.

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Ichthyotoxic red tide is a problem that the world is facing and needs to solve. The use of antialgal compounds from marine macroalgae to suppress ichthyotoxic red tide is considered a promising biological control method. Antialgal substances were screened and isolated from , , , , , , and sp.

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Chromite ore processing residue (COPR) is a typical hazardous waste, which contains Cr(vi) and poses a great threat to the ecological environment and human health. In this study, solidification/stabilization (S/S) of COPR was carried out by using blast furnace slag (BFS) and fly ash (FA) to prepare alkali-activated cementitious materials (AACM). The influence of different factors (water glass modulus, liquid-solid ratio, alkali-solid content and curing temperature) on compressive strength was investigated by single-factor experiment.

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The Preparation of g-CN/ZnInS Nano-Heterojunctions and Their Enhanced Efficient Photocatalytic Hydrogen Production.

Molecules

May 2024

Co-Innovation Center of Jiangsu Marine Bio-Industry Technology, Jiangsu Ocean University, 59 Cangwu Road, Haizhou, Lianyungang 222005, China.

Hydrogen production technology has triggered a research boom in order to alleviate the problems of environmental pollution and the pressure on non-renewable energy sources. The key factor of this technology is the use of an efficient photocatalyst. g-CN is a typical semiconductor photocatalytic material that is non-toxic and environmentally friendly and does not cause any serious harm to human beings.

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PEG modification increases thermostability and inhibitor resistance of Bst DNA polymerase.

Biosci Biotechnol Biochem

June 2024

Jiangsu Key Laboratory of Marine Biological Resources and Environment, Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, Jiangsu Ocean University, Lianyungang, China.

Polyethylene glycol modification (PEGylation) is a widely used strategy to improve the physicochemical properties of various macromolecules, especially protein drugs. However, its application in enhancing the performance of enzymes for molecular biology remains underexplored. This study explored the PEGylation of Bst DNA polymerase, determining optimal modification reaction conditions.

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Extraction, Isolation and Biological Activity of Two Glycolipids from .

Mar Drugs

March 2024

Jiangsu Key Laboratory of Marine Bioresources and Eco-Environment, Jiangsu Ocean University, Lianyungang 222005, China.

In order to explore the extraction and activity of macroalge glycolipids, six macroalgae (, , , , sp. and ) glycolipids were extracted with five different solvents firstly. Considering the yield and glycolipids concentration of extracts, , sp.

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Ferulic acid alleviates avermectin induced renal injury in carp by inhibiting inflammation, oxidative stress and apoptosis.

Fish Shellfish Immunol

June 2024

Jiangsu Key Laboratory of Marine Bioresources and Environment, Co-Innovation Center of Jiangsu Marine Bio-industry Technology, Jiangsu Marine Pharmaceutical Resources Development Engineering Research Center, Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, College of Pharmacy, Jiangsu Ocean University, Lianyungang, 222005, China; Jiangsu Institute of Marine Resources Development, Lianyungang, 222005, China. Electronic address:

Avamectin (AVM), a macrolide antibiotic, is widely used in fisheries, agriculture, and animal husbandry, however, its irrational use poses a great danger to aquatic organisms. Ferulic acid (FA) is a natural chemical found in the cell walls of plants. It absorbs free radicals from the surrounding environment and acts as an antioxidant.

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Optimization of α-L-arabinofuranosidase CcABF on clarification and beneficial active substances in fermented ginkgo kernel juice by artificial neural network and genetic algorithm.

Food Chem

August 2024

Jiangsu Key Laboratory of Marine Bioresources and Environment, Jiangsu Ocean University, Lianyungang 222005, China; Co-Innovation Center of Jiangsu Marine Bio-industry Technology, Jiangsu Ocean University, Lianyungang 222005, China; Jiangsu Institute of Marine Resources Development, Jiangsu Ocean University, Lianyungang 222005, China. Electronic address:

This study aimed at using α-L-arabinofuranosidase CcABF to improve the clarity and active substances in fermented ginkgo kernel juice by artificial neural network (ANN) modeling and genetic algorithm (GA) optimization. A credible three-layer feedforward ANN model was established to predict the optimal parameters for CcABF clarification. The experiments proved the highest transmittance of 89.

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In this study, walnut shell (WS) was used as feedstock, incorporating lithium carbonate (LC), sodium carbonate (SC), potassium carbonate (PC), and potassium hydroxide (PH) as pyrolysis catalysts and carbonization activators. A one-step method that allows catalytic pyrolysis and carbonization to be carried out consecutively under their respective optimal conditions is employed, enabling the concurrent production of high-quality pyrolysis oil, pyrolysis gas, and carbon materials from biomass conversion. The effects of LC, SC, PC, and PH on the yield and properties of products derived from WS pyrolysis as well as on the properties and performance of the resulting carbon materials were examined.

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Spent lithium-ion batteries (LIBs) are an essential secondary resource containing valuable metal elements. Transforming spent LIBs into efficient catalysts through a simple process presents a promising strategy to address both metal resource scarcity and clean energy challenges. Herein, a deep eutectic solvent-assisted synthesis of CoO material from spent LIBs is proposed.

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Effects of culture temperature and light regimes on biomass and lipid accumulation of Chlamydomonas reinhardtii under carbon-rich and nitrogen-limited conditions.

Bioresour Technol

May 2024

State Key Laboratory of Crop Stress Adaptation and Improvement, School of Life Sciences, Henan University, Kaifeng 475004, China; Academy for Advanced Interdisciplinary Studies, Henan University, Kaifeng 475004, China. Electronic address:

This study investigated the impacts of various culture temperatures and light regimes on growth and biochemical constituents of Chlamydomonas reinhardtii under carbon-supply and nitrogen-limited conditions to improve oil production in algal cells. Results displayed that under a 30 ℃ and 150 μE/m/s regime, there was a significant increase in biomass, total lipids, and lipid productivity. Specifically, these parameters reached 1.

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Anti-vibriosis bioactive molecules from marine-derived variant sp. ZZ741A.

Nat Prod Res

March 2024

Jiangsu Key Laboratory of Marine Biotechnology/Jiangsu Key Laboratory of Marine Bioresources and Environment, Jiangsu Ocean University, Lianyungang, PR China.

The infection of is an important cause of huge economic losses in aquaculture industry. At present, antibiotics are mainly used to prevent and reduce the infection of the , which has accelerated the emergence of multi-drug-resistant strains. New generation alternative anti- drugs were in urgent to solve this problem.

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In this study, the grain boundary character distribution (GBCD) of a B10 alloy was optimized, employing thermomechanical processing consisting of friction stirring processing (FSP) and annealing treatment. Using electron backscatter diffraction, the effects of rotational speed of FSP and annealing time on the evolution of GBCD were systematically investigated. The GBCD evolution was analyzed concerning various parameters, such as the fraction of low-Σ coincidence site lattice (CSL) boundaries, the average number of grains per twin-related domain (TRD), the length of longest chain (LLC), and the triple junction distribution.

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Morphological and Molecular Changes during Limb Regeneration of the .

Animals (Basel)

February 2024

Jiangsu Key Laboratory of Marine Biotechnology, Jiangsu Ocean University, Lianyungang 222005, China.

With the increase in breeding density of , appendage breakage may occur, which seriously affects survival and economic benefits. To study the limb regeneration process of , we induced autotomy of the pereopods. After a period of time, wound swelling disappeared, the pigment gradually accumulated, and a tawny film subsequently formed in the wound.

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Ferulic acid attenuates difenoconazole exposure induced liver injury in carp by modulating oxidative damage, inflammation and apoptosis.

Comp Biochem Physiol C Toxicol Pharmacol

June 2024

Jiangsu Key Laboratory of Marine Bioresources and Environment, Co-Innovation Center of Jiangsu Marine Bio-industry Technology, Jiangsu Marine Pharmaceutical Resources Development Engineering Research Center, Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, College of Pharmacy, Jiangsu Ocean University, Lianyungang 222005, China; Jiangsu Institute of Marine Resources Development, Lianyungang 222005, China. Electronic address:

Difenoconazole (DFZ) is a widely used triazole fungicide in agricultural production. However, the presence of DFZ residue in the environment poses a significant risk to non-target organisms. Ferulic acid (FA) is a phenolic compound known for its antioxidant and anti-inflammatory properties.

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Bimetal doped Cu-Fe-zeolitic imidazole framework-8 (ZIF-8)/graphitic carbon nitride (GCN) (Cu-Fe-ZIF-8/GCN) nanocomposites were prepared one-pot and ion-exchange methods. The main influencing factors, such as adsorbent concentration, TC concentration, initial pH, and coexisting ions, were evaluated in detail. Due to the suitable pore structures and the presence of multiple interactions on the surface, the nanocomposite showed a high adsorption capacity up to 932 mg g for tetracycline hydrochloride (TC), outperforming ZIF-8 by 4.

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