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[Clinical Significance of RAS Gene Mutations in Patients with Acute Myeloid Leukemia].

Zhongguo Shi Yan Xue Ye Xue Za Zhi

October 2022

Department of Hematology, Lianyungang First People's Hospital; Department of Hematology, The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology. Lianyungang 222000, Jiangsu Province, China,E-mail:

Objective: To investigate the clinical characteristics of RAS gene mutations in patients with acute myeloid leukemia (AML).

Methods: 43 myeloid gene mutations were detected using next-generation sequencing (NGS) in 180 patients with AML who were first diagnosed between May 2011 and February 2021. The molecular and clinical features of RAS gene mutations and their effects on efficacy and survival of patients were retrospectively analyzed.

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