117 results match your criteria: "Jesus College[Affiliation]"

We investigated which parts of the cerebellum are involved in formulating and articulating sentences using (i) a sentence production task that involved describing simple events in pictures; (ii) an auditory sentence repetition task involving the same sentence articulation but not sentence formulation; and (iii) an auditory sentence-to-picture matching task that involved the same pictorial events and no overt articulation. Activation for each of these tasks was compared to the equivalent word processing tasks: noun production, verb production, auditory noun repetition, and auditory noun-to-picture matching. We associate activation in bilateral cerebellum lobule VIIb with sequencing words into sentences because it increased for sentence production compared to all other conditions and was also activated by word production compared to word matching.

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Tuberculosis (TB) is a chronic and pathogenic disease that leads to life-threatening situations like death. Many people have been affected by TB owing to inaccuracy, late diagnosis, and deficiency of treatment. The early detection of TB is important to protect people from the severity of the disease and its threatening consequences.

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Detection of non-cardiac fetal abnormalities on ultrasound at 11-14 weeks: systematic review and meta-analysis.

Ultrasound Obstet Gynecol

July 2024

Oxford Maternal and Perinatal Health Institute, Green Templeton College, University of Oxford, Oxford, UK.

Article Synopsis
  • The study aimed to evaluate the effectiveness of 2D ultrasound as a screening tool for various fetal anomalies during the 11-14 weeks of pregnancy, while also examining factors that might influence screening success.
  • It involved a systematic review and meta-analysis of 52 studies, encompassing over 500,000 fetuses, to gauge the accuracy of detecting 16 specific congenital anomalies, using a postnatal or postmortem reference standard.
  • Findings indicated that while some severe anomalies had very high detection rates (like acrania at 98% and gastroschisis at 96%), not all conditions were as easily detected during the first trimester.
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The possibility of neurotechnological interference with our brain and mind raises questions about the moral rights that would protect against the (mis)use of these technologies. One such moral right that has received recent attention is the right to mental integrity. Though the metaphysical boundaries of the mind are a matter of live debate, most defences of this moral right seem to assume an internalist (brain-based) view of the mind.

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How moral bioenhancement affects perceived praiseworthiness.

Bioethics

February 2024

Oxford Uehiro Centre for Practical Ethics, Faculty of Philosophy, University of Oxford, Oxford, UK.

Psychological literature indicates that actions performed with the assistance of cognition-enhancing biomedical technologies are often deemed to be less praiseworthy than similar actions performed without such assistance. This study examines (i) whether this result extends to the bioenhancement of moral capacities, and (ii) if so, what explains the effect of moral bioenhancement on perceived praiseworthiness. The findings indicate that actions facilitated by morally bioenhanced individuals are considered less deserving of praise than similar actions facilitated by 'traditional' moral enhancement-for example, moral self-education.

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Interpretable many-class decoding for MEG.

Neuroimage

November 2023

Oxford Centre for Human Brain Activity, Department of Psychiatry, University of Oxford, OX3 7JX, Oxford, UK; Wellcome Centre for Integrative Neuroimaging, OX3 9DU, Oxford, UK. Electronic address:

Multivariate pattern analysis (MVPA) of Magnetoencephalography (MEG) and Electroencephalography (EEG) data is a valuable tool for understanding how the brain represents and discriminates between different stimuli. Identifying the spatial and temporal signatures of stimuli is typically a crucial output of these analyses. Such analyses are mainly performed using linear, pairwise, sliding window decoding models.

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Edith Stein has written a great deal about the nature of women and has advocated for the place of women in society and their place in the professions. We have written a series of papers describing the relationship between the findings of neuroscience and the differences between the female and male brains. Here we summarise how our knowledge of these differences underpin Edith Stein's view of the nature of women, and therefore validate Stein's particular view of feminism.

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Group-level brain decoding with deep learning.

Hum Brain Mapp

December 2023

Oxford Centre for Human Brain Activity, Department of Psychiatry, University of Oxford, Oxford, UK.

Decoding brain imaging data are gaining popularity, with applications in brain-computer interfaces and the study of neural representations. Decoding is typically subject-specific and does not generalise well over subjects, due to high amounts of between subject variability. Techniques that overcome this will not only provide richer neuroscientific insights but also make it possible for group-level models to outperform subject-specific models.

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What makes a medical intervention invasive?

J Med Ethics

March 2024

Faculty of Philosophy, Oxford Uehiro Centre for Practical Ethics, University of Oxford, Oxford, UK

The classification of medical interventions as either invasive or non-invasive is commonly regarded to be morally important. On the most commonly endorsed account of invasiveness, a medical intervention is invasive if and only if it involves either breaking the skin ('incision') or inserting an object into the body ('insertion'). Building on recent discussions of the concept of invasiveness, we show that this standard account fails to capture three aspects of existing usage of the concept of invasiveness in relation to medical interventions-namely, (1) usage implying that invasiveness comes in degrees, (2) that the invasiveness of an intervention can depend on the characteristics of the salient alternative interventions, and (3) that medical interventions can be invasive in non-physical ways.

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Objective: Sexual misconduct adversely affects the mental and physical health of millions of people each year and has been declared a global pandemic. Incidence in both educational and clinical settings remains high. In the last 5 years, the NHS spent over £4 million settling sexual misconduct-related claims.

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Objective: Reports identify that sexual harassment is troublingly pervasive in the NHS. Active bystander training (ABT) has been promoted to address sexual harassment, alongside other forms of poor behaviour, discrimination, and harassment. We explore ABT across all English NHS Trusts and determine whether the programmes address sexual misconduct in the training content.

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The United Nations (UN) recognises free school meals as critical, yet widely disrupted by COVID-19. We investigate caregiver perceptions and responses to interruptions to the universal infant free school meal programme (UIFSM) in Cambridgeshire, England, using an opt-in online survey. From 586 responses, we find 21 per cent of respondents' schools did not provide UIFSM after lockdown or advised caregivers to prepare packed lunches.

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The Mere Substitution Defence of Nudging Works for Neurointerventions Too.

J Appl Philos

July 2022

Oxford Uehiro Centre for Practical Ethics Faculty of Philosophy, University of Oxford Oxford UK.

Nudges are often defended on the basis that they merely substitute existing influences on choice with other influences that are similar in kind; they introduce no new kind of influence into the choice situation. I motivate the view that, if this defence succeeds in establishing the moral innocuousness of typical nudges, it also establishes the moral innocuousness of an intuitively wrongful neurochemical intervention. I then consider two attempts to rebut this view and argue that both fail.

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Objectives: Research identifies that multinational corporations, including The Coca-Cola Company ('Coca-Cola'), seek to influence public health research and policy through scientific events, such as academic and professional conferences. This study aims to understand how different forms of funding and sponsorship impact the relationship between Coca-Cola, academic institutions, public health organisations, academics and researchers.

Design: The study was conducted using Freedom of Information (FOI) requests and systematic website searches.

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The Expressivist Objection to Nonconsensual Neurocorrectives.

Crim Law Philos

April 2021

The Oxford Uehiro Centre for Practical Ethics, University of Oxford, Suite 8, Littlegate House 16/17 St Ebbe's Street, Oxford, OX1 1PT UK.

Neurointerventions-interventions that physically or chemically modulate brain states-are sometimes imposed on criminal offenders for the purposes of diminishing the risk that they will recidivate, or, more generally, of facilitating their rehabilitation. One objection to the nonconsensual implementation of such interventions holds that this expresses a disrespectful message, and is thus impermissible. In this paper, we respond to this objection, focusing on the most developed version of it-that presented by Elizabeth Shaw.

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Using fMRI, we investigated how right temporal lobe gliomas affecting the posterior superior temporal sulcus alter neural processing observed during speech perception and production tasks. Behavioural language testing showed that three pre-operative neurosurgical patients with grade 2, grade 3 or grade 4 tumours had the same pattern of mild language impairment in the domains of object naming and written word comprehension. When matching heard words for semantic relatedness (a speech perception task), these patients showed under-activation in the tumour infiltrated right superior temporal lobe compared to 61 neurotypical participants and 16 patients with tumours that preserved the right postero-superior temporal lobe, with enhanced activation within the (tumour-free) contralateral left superior temporal lobe.

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What is Criminal Rehabilitation?

Crim Law Philos

October 2020

Oxford Uehiro Centre for Practical Ethics, Faculty of Philosophy, University of Oxford, Suite 8, Littlegate House, 16/17 St. Ebbe's St., Oxford, OX1 1PT UK.

It is often said that the institutions of criminal justice ought or-perhaps more often-ought not to criminal offenders. But the term 'criminal rehabilitation' is often used without being explicitly defined, and in ways that are consistent with widely divergent conceptions. In this paper, we present a taxonomy that distinguishes, and explains the relationships between, different conceptions of criminal rehabilitation.

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Conceptualisation of health inequalities by local healthcare systems: A document analysis.

Health Soc Care Community

November 2022

Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.

In 2019, local healthcare systems in England were asked to develop formal plans to reduce health inequalities. Here, we explore plans to understand how local healthcare systems conceptualise health inequalities and why. A broad Internet search and targeted search of NHS websites were conducted to identify all publicly accessible healthcare planning documents (National Health Service (NHS) Long-Term Plan (LTP) response documents) produced by local health partnerships in England.

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