116 results match your criteria: "Jessner Lymphocytic Infiltration of the Skin"
Lupus Erythematosus Tumidus Misdiagnosed as Erythema Nodosum from Coccidioidomycosis.
Case Rep Dermatol
May 2024
Department of Public Health and Preventive Medicine, St. George's University School of Medicine, St. George, Grenada.
Article Synopsis
- Lupus erythematosus tumidus (LET) is a rare skin condition that can be difficult to diagnose due to its similarities with other skin disorders.
- A case involving a 52-year-old Hispanic female revealed that she was initially misdiagnosed with erythema nodosum and treated ineffectively before tests confirmed LET.
- The patient responded well to treatment with hydroxychloroquine, highlighting the importance of confirmatory testing before starting treatment for skin conditions like LET.
Lupus Erythematosus Tumidus as a Distinct Uncommon Subtype of Cutaneous Lupus Erythematosus: A Case Report and Review.
Cureus
April 2024
Dermatopathology, Riverchase Dermatology, Fort Myers, USA.
Lupus erythematosus tumidus (LET) is an uncommon but distinct photosensitive subtype of cutaneous lupus erythematosus (CLE). It differs from discoid and subacute cutaneous lupus erythematosus (SCLE) clinically and pathologically. LET is marked by extreme photosensitivity and carries a much lower risk of progression to systemic disease.
View Article and Find Full Text PDFAtypical skin conditions of the neck and back as a dermal manifestation of anti-HMGCR antibody-positive myopathy.
BMC Immunol
May 2024
Department of Neurology, NHO Kure Medical Center, Chugoku Cancer Center, Kure, Japan.
Article Synopsis
- Immune-mediated necrotizing myopathy (IMNM) is an inflammatory muscle disease that typically doesn't present with skin rashes, but patients with the specific HMGCR antibody may exhibit atypical skin conditions.
- A study of 100 IIM patients revealed that 34% had skin conditions, with 42% of those with HMGCR-IMNM showing atypical lesions, which were distinct from typical IIM-related rashes.
- Skin biopsies from HMGCR-IMNM patients revealed similar microscopic features, specifically Bcl-2-positive lymphocyte infiltrations, suggesting that these atypical skin manifestations could be a clue for diagnosing HMGCR-IMNM.
Mimicking Rosacea? Jessner's Lymphocytic Infiltration of the Skin: A Case Report.
Clin Cosmet Investig Dermatol
April 2024
Department of Dermatology, The First Affiliated Hospital of Kunming Medical University Kunming, Kunming, People's Republic of China.
Article Synopsis
- A 35-year-old woman developed a rash with symptoms similar to rosacea, including red papules and plaques on her face, lasting for a year.
- A biopsy showed significant inflammation with a high number of CD4+ T cells, leading to a diagnosis of Jessner's Lymphocytic Infiltration of the Skin (JLIS).
- The patient was treated with oral Minocycline, which cleared the rash within two months, and there has been no recurrence for the past 5 years.
Jessner's Lymphocytic Infiltration of the Skin in a 73-Year-Old Woman: A Case Report.
Am J Case Rep
April 2023
School of Medicine, Pontificia Universidad Católica del Ecuador, Quito, Ecuador.
Article Synopsis
- Jessner's lymphocytic infiltration of the skin (JLIS) is a rare, benign skin disorder typically affecting young adults, but little is known about its demographics and causes.
- A 73-year-old female presented with an asymptomatic skin lesion after an insect sting, initially misdiagnosed and treated as an abscess.
- The correct diagnosis of JLIS was confirmed through a biopsy, and after treatment with triamcinolone injections and sunscreen, the lesion completely healed without any recurrence.
Anti-HMGCR myopathy: clinical and histopathological features, and prognosis.
Curr Opin Rheumatol
November 2021
Department of Neurology, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Kure, Hiroshima, Japan.
Purpose Of Review: This review aims to describe clinical and pathological features, prognosis and treatment in patients with anti-HMGCR antibody positive immune-mediated necrotizing myopathy (HMGCR-IMNM) based on recent findings.
Recent Findings: Using advances in diagnostic modalities that can confirm the presence of anti-HMGCR antibody, the clinical and pathological manifestations of HMGCR-IMNM were found to be broader than previously reported. Although only a small percentage of HMGCR-IMNM patients present with atypical manifestations, some of these patients show slow disease progression and clinical symptoms, which are similar to those of limb-girdle muscular dystrophies.
Three Cases of Lymphocytic Infiltration of the Eyelid.
Dermatopathology (Basel)
May 2021
Department of Dermatology, Graduate School of Medicine, Mie University, Tsu, Mie 514-8507, Japan.
Article Synopsis
- Lymphocytic infiltration of the skin (LIS) is a condition first described in 1953, marked by red bumps and plaques mainly on the head, neck, and upper back, with a specific skin biopsy result showing lymphocyte accumulation in the dermis.
- Recent cases involved a 69-year-old man and a 21-year-old woman with swollen eyelids, both showing CD4+ T cells in their biopsies, while a 68-year-old man's biopsy revealed CD8+ T cells, indicating different immune responses based on the duration of the condition.
- Treatment with daily oral methylprednisolone (8-16 mg) effectively reduced swelling and redness in these patients, suggesting that CD8+ T cells could play
Primary Cutaneous CD4-Positive Small/Medium T-Cell Lymphoproliferative Disorder Mimicking Jessner Lymphocytic Infiltrate and Tumid Lupus-A Report of Two Cases.
Am J Dermatopathol
December 2021
Department of Pathology and Dermatology, University of Virginia Health System, Charlottesville, VA.
Article Synopsis
- Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder is a benign condition featuring small to medium pleomorphic cells that resemble follicular helper T-cells.
- Two cases are discussed where this disorder presented with high levels of dermal mucin, resembling other skin conditions such as Jessner lymphocytic infiltrate and tumid lupus.
- The report emphasizes the importance of differential diagnosis and outlines distinguishing features to differentiate this disorder from similar conditions.
Jessner's lymphocytic infiltration as a symptom of Immune Reconstitution Inflammatory Syndrome in an HIV-infected patient: A case report.
Dermatol Ther
July 2020
Department of Pathology, Faculty of Medicine, Selcuk University, Konya, Turkey.
Cutaneous Pseudolymphoma Due to Hirudotherapy.
Turkiye Parazitol Derg
March 2019
Necmettin Erbakan Univercity Meram Faculty of Medicine, Department of Pathology, Konya, Türkiye
Article Synopsis
- * A case study reported a 52-year-old male who developed skin plaques after receiving leech therapy (hirudotherapy) on his neck, which was later diagnosed as Jessner's lymphocytic infiltration following a skin biopsy.
- * As the popularity of hirudotherapy grows, the likelihood of side effects, like the one experienced by the patient, may rise, highlighting the importance of understanding its indications and contraindications in clinical settings.
Lymphoma or pseudolymphoma: A report of six cases and review of the literature.
Dermatol Ther
July 2019
Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Article Synopsis
- - The study aimed to compare cutaneous pseudolymphomas (CPL) with primary cutaneous lymphomas by analyzing clinical presentations and pathologic features from six cases observed at Peking Union Medical College Hospital in 2018.
- - Different clinical manifestations and pathologic characteristics included atypical lymphocyte infiltration, with some cases resembling mycosis fungoides or other types of lymphomas; causes of CPL varied from insect bites to drug reactions.
- - Treatment involved glucocorticoids, leading to significant improvement in skin lesions and symptoms, with long-term follow-up showing no relapses, indicating that CPLs share similarities with cutaneous lymphomas and typically have a good prognosis.
Jessner-Kanof lymphocyte infiltration responded well to impulse intralesional corticosteroid.
Dermatol Ther
November 2018
Department of Dermatology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Jessner lymphocytic infiltration - rare in childhood.
Dermatol Online J
October 2017
Department of Dermatology and Allergy Centre, Odense University Hospital, Denmark.
Article Synopsis
- - A 13-year-old girl has been diagnosed with Jessner lymphocytic infiltrate of the skin, a rare condition that she has had since she was 9 years old.
- - The paper discusses the clinical features associated with this skin condition, which are not commonly seen in children.
- - It also emphasizes the effectiveness of tacrolimus as a treatment option for managing the condition.
Etanercept-Induced Lymphocytic Infiltration of Jessner-Kanof.
Arthritis Rheumatol
March 2018
Centre Hospitalier de Valenciennes, Valenciennes, France.
The Histopathological Spectrum of Pseudolymphomatous Infiltrates in Cutaneous Lupus Erythematosus.
Am J Dermatopathol
April 2018
Research Unit Dermatopathology, Department of Dermatology, Medical University of Graz, Graz, Austria.
Article Synopsis
- * Findings reveal various patterns of infiltrates: 60% had dense nodular infiltrates, 20% showed angiocentric patterns with atypical lymphoid cells, and 13.3% exhibited band-like features similar to mycosis fungoides.
- * Histological clues for diagnosis include interface dermatitis and clusters of specific cells, highlighting the need for careful analysis to avoid misdiagnosis, particularly distinguishing from aggressive lymphomas or mycosis fungoides.
Mepacrine as successful monotherapy for refractory Jessner-Kanof disease: still an important drug in the dermatologic armamentarium.
J Dermatolog Treat
May 2017
a Department of Dermatology , University Hospital Antwerp (UZA), University of Antwerp (UA), Antwerp , Belgium.
Article Synopsis
- Jessner-Kanof disease (JKD) is a hard-to-treat skin condition characterized by lymphocytic infiltration, and mepacrine, an anti-malarial, shows promise as a treatment option, particularly where other therapies fail.
- Two female patients with persistent, biopsy-confirmed JKD were treated with daily mepacrine, leading to noticeable improvement within a month and complete remission by four months, all without significant side effects.
- Mepacrine appears effective and safe for managing JKD and similar conditions, emphasizing the need for its availability in Belgium due to its minimal side effects and lack of retinal toxicity.
Unilateral unique Lupus tumidus: pathogenetic mystery and diagnostic problem.
Wien Med Wochenschr
May 2016
Policlinic for Dermatology and Venereology, University Hospital Lozenetz, Koziak street 1, 1407, Sofia, Bulgaria.
Article Synopsis
- Lupus tumidus is a rare immune disorder that shares characteristics with chronic cutaneous lupus erythematosus, though its exact causes are unclear.
- Diagnosing lupus tumidus involves ruling out other similar conditions, which can be complicated due to overlapping symptoms.
- A 42-year-old patient with an unusual case of lupus tumidus achieved complete remission after treatment with hydroxychloroquine and using a high-SPF sunscreen over two months.
Differentiation of Jessner's Lymphocytic Infiltration of the Skin from Various Chronic Cutaneous Lupus Erythematosus Subtypes by Quantitative Computer-Aided Image Analysis.
Dermatology
December 2016
Department of Dermatology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea.
Article Synopsis
- Researchers explored the differences between chronic cutaneous lupus erythematosus and Jessner's lymphocytic infiltration of the skin through objective analysis.
- They used clinical photos and computer-aided image analysis to measure erythema and assess histological images.
- The study found no significant differences between the two skin conditions, indicating that current methods of quantitative analysis may not effectively differentiate them.
Possibly drug-induced palpable migratory arciform erythema.
An Bras Dermatol
January 2016
Hospital do Servidor Público Estadual, São Paulo, SP, BR.
Article Synopsis
- Palpable migratory arciform erythema is a rare skin condition with unclear causes and has limited documented cases.
- It shares similar clinical and histopathological features with other skin diseases, making diagnosis challenging.
- The first reported Brazilian cases exhibited annular plaques and red arcs that grew outward before fading away, occurring repeatedly over the years, suggesting a possible connection to medication.
Duloxetine-induced pseudolymphoma with features of lymphocytic infiltration of Jessner-Kanof.
Acta Derm Venereol
September 2014
Department Medical Sciences, Section of Dermatology, University of Ferrara, Via Savonarola 9, IT-44123 Ferrara, Italy.
[Current therapeutic indications of thalidomide and lenalidomide].
Med Clin (Barc)
April 2014
Servicio de Clínica Médica, Hospital Provincial del Centenario, Facultad de Ciencias Médicas, Universidad Nacional de Rosario, Rosario, Argentina.
Article Synopsis
- Thalidomide, introduced in 1956 as a safe over-the-counter sedative, was removed from the market after being linked to severe birth defects.
- Despite its controversial history, thalidomide has been FDA-approved for treating conditions like leprosy and multiple myeloma, as well as various unresponsive dermatological issues.
- The paper reviews thalidomide's history, pharmacology, clinical uses, mechanisms, and side effects, while also mentioning the development of new analogues that lack extensive clinical experience.
The efficacy of pulsed dye laser treatment for inflammatory skin diseases: a systematic review.
J Am Acad Dermatol
October 2013
Department of Dermatology, Amphia Hospital Breda, Breda, The Netherlands. Electronic address:
Article Synopsis
- The study aimed to systematically review the effectiveness of pulsed dye laser (PDL) treatment for various inflammatory skin diseases due to a lack of clear evidence-based guidelines.
- A total of 52 articles were reviewed, covering conditions like psoriasis, acne vulgaris, and lupus erythematodes, with PDL showing effectiveness for localized plaque psoriasis and acne vulgaris (grade B recommendation).
- Despite promising results for other inflammatory conditions, the evidence was less robust, primarily due to the absence of randomized controlled trials, leading to a lower recommendation level (grade C).
[Palpable arciforme migratory erythema].
Hautarzt
December 2012
Klinik für Dermatologie, Allergologie und Phlebologie, Klinikum Bremerhaven Reinkenheide, Postbrookstr. 103, 27574, Bremerhaven, Deutschland.
Article Synopsis
- A 39-year-old man was diagnosed with a rare skin condition called palpable migratory arciform erythema, characterized by a circular red rash on his chest.
- This condition is a type of T-cell pseudolymphoma and its classification as a distinct entity or variant is still debated among experts.
- Treatment options typically include topical corticosteroids or oral antibiotics, but in this case, UV-A1 therapy resulted in a complete healing of the rash.
Jessner lymphocytic infiltrate as a side effect of bee venom immunotherapy.
J Investig Allergol Clin Immunol
March 2014
Allergy and Clinical Immunology Unit, Antalya Education and Training Hospital, Antalya, Turkey.