1 results match your criteria: "Jeroen Bosch Hospital (Ioc GZG)[Affiliation]"
Intrinsic defect of the immune system in children with Down syndrome: a review.
Clin Exp Immunol
May 2009
Department of Paediatrics, Jeroen Bosch Hospital (Ioc GZG), Hertogenbosch, the Netherlands.
Article Synopsis
- Down syndrome (DS) is the leading cause of mental retardation, with immunological changes noted since the 1970s.
- The neurological system in individuals with DS seems to age faster, even showing signs of Alzheimer’s disease earlier than usual.
- Current research suggests that the immune system in DS patients may be inherently deficient from the start, rather than just a consequence of aging.