Inhibitory effects of nodakenin on inflammation and cell death in lipopolysaccharide-induced liver injury mice.

Background: Nodakenin, a coumarin glucoside isolated from the roots of Angelica biserrata, has been reported to have anti-inflammatory, antibacterial, anticancer effects. However, despite these studies, the potential liver protective effects of nodakenin in inflammatory liver injury models have not been reported.

Methods: A mouse model of inflammatory liver injury was induced by injection of lipopolysaccharide (LPS) (15 mg/kg, intraperitoneally (i.

Extract of Suppresses Mast Cell-Mediated Allergic Inflammation by Inhibiting Mitogen-Activated Protein Kinase and Nuclear Factor-κB.

Mast cells are effector cells that initiate allergic inflammatory immune responses by inducing inflammatory mediators. (Linn.) Gaudich is a natural herb in the nettle family Urticaceae that possesses numerous pharmacological properties.

The influence of structural disorder and phonon on metal-to-insulator transition of VO .

We used temperature-dependent x-ray absorption fine structure (XAFS) measurements to examine the local structural properties around vanadium atoms at the V K edge from VO films. A direct comparison of the simultaneously-measured resistance and XAFS regarding the VO films showed that the thermally-driven structural transition occurred prior to the resistance transition during a heating, while  this change simultaneously occured during a cooling. Extended-XAFS (EXAFS) analysis revealed significant increases of the Debye-Waller factors of the V-O and V-V pairs in the {111} direction of the R-phase VO that are due to the phonons of the V-V arrays along the same direction in a metallic phase.