4 results match your criteria: "Jefferson Kimmel Medical School[Affiliation]"
DANON DISEASE: A MODEL OF PHOTORECEPTOR DEGENERATION SECONDARY TO PRIMARY RETINAL PIGMENT EPITHELIUM DISEASE.
Retin Cases Brief Rep
November 2022
University of Pennsylvania, Philadelphia, Pennsylvania.
Purpose: To describe in detail the retinal phenotype of LAMP2-associated Danon disease.
Methods: Three LAMP2-positive patients from two unrelated families were studied with spectral-domain optical coherence tomography and with short-wavelength and near-infrared fundus autofluorescence (FAF) imaging. Visual function was measured with full-field electroretinography and chromatic perimetry.
CHOROIDAL AMYLOID DEPOSITION: A Multicenter Study of Amyloid Lesions Identified in Late Indocyanine Green Angiography.
Retina
October 2022
Department of Ophthalmology, Wills Eye Hospital, Jefferson Kimmel Medical School, Philadelphia, Pennsylvania.
Article Synopsis
- The study aimed to describe choroidal amyloid angiopathy (CAA) using late-phase indocyanine green angiography (ICGA) in patients with transthyretin (ATTR) and AL amyloidosis.
- A total of 32 patients were evaluated; hyperfluorescent spots indicating CAA were found in 89% of the eyes, with a median time to peak staining of 672 seconds, significantly longer than initial staining.
- Most patients showed improvement in CAA during treatment, suggesting it may reflect systemic disease status, although some developed complications like vitreous opacities and glaucoma.
SURGICAL OUTCOMES OF VASOPROLIFERATIVE RETINAL TUMORS' REFRACTORY TO NONINVASIVE THERAPIES.
Retina
September 2022
Department of Ophthalmology, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Purpose: To evaluate the outcomes of surgical treatment of refractory vasoproliferative retinal tumors (VPTs) and its complications.
Methods: Clinical charts of all patients diagnosed with VPTs who underwent surgical treatment from 2005 to 2020 were reviewed. Clinical features, surgical techniques, and outcomes were evaluated.
ASSOCIATION BETWEEN CHOROIDAL CHARACTERISTICS AND SYSTEMIC SEVERITY IN AMYLOIDOSIS.
Retina
May 2021
Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota.
Purpose: This study aimed to describe the choroidal features of ocular amyloidosis using multimodal imaging, to correlate these findings with systemic involvement, and to propose a choroidal grading system.
Methods: Eleven patients with systemic amyloidosis were reviewed retrospectively. Each case was assigned a grade according to the severity of choroidal findings as determined by both enhanced depth imaging optical coherence tomography and indocyanine green angiography.