172 results match your criteria: "Jawaharlal Nehru Institute of Postgraduate Medical Education & Research[Affiliation]"

Background: A pooled estimate of stunting prevalence in refugee and internally displaced under-five children can help quantify the problem and focus on the nutritional needs of these marginalized groups. We aimed to assess the pooled prevalence of stunting in refugees and internally displaced under-five children from different parts of the globe.

Methods: In this systematic review and meta-analysis, seven databases (Cochrane, EBSCOHost, EMBASE, ProQuest, PubMed, Scopus, and Web of Science) along with "preprint servers" were searched systematically from the earliest available date to 14 February 2023.

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Tissue-specific implications of SARS-CoV-2-encoded accessory proteins are not fully understood. SARS-CoV-2 infection can severely affect three major organs-the heart, lungs, and brain. We analyzed SARS-CoV-2 ORF3a interacting host proteins in these three major organs.

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Article Synopsis
  • A study was conducted in India to investigate sudden unexplained deaths among healthy young adults (ages 18-45) possibly linked to COVID-19 infection or vaccination from October 2021 to March 2023.
  • The research analyzed data from 729 cases and 2,916 matching controls, assessing factors like COVID-19 vaccination status, family history, substance use, and physical activity.
  • Results indicated that receiving at least one COVID-19 vaccine dose reduced the likelihood of sudden death, while factors such as past hospitalization for COVID-19, family history of sudden deaths, binge drinking, and intense physical activity increased the risk.
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Cardiovascular consequences of financial stress: A systematic review and meta-analysis.

Curr Probl Cardiol

February 2024

Tribhuvan University Teaching Hospital, Kathmandu 46000, Nepal; Department of Clinical Microbiology, DY Patil Medical College, Hospital and Research Centre, DY Patil Vidyapeeth, Pune, Maharashtra 411000, India.

Background: Cardiovascular diseases (CVD), notably coronary artery disease (CAD) and coronary heart disease (CHD), are predominant contributors to global morbidity and mortality. Financial stress is recognized as a non-traditional risk factor for CVD. The objective of this study is to conduct a systematic review and meta-analysis on the association between financial stress and the incidence of major cardiac outcomes.

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(1) Background: Understanding the physicians' knowledge, attitudes, and antimicrobial prescribing behavior is a crucial step towards designing strategies for the optimal use of these agents. (2) Methods: A cross-sectional online survey was conducted among clinicians across India between May and July 2022 using a self-administered questionnaire in English comprising 35 questions pertaining to demographic characteristics, knowledge, attitude, and practices domains. (3) Results: A total of 544 responses were received from 710 physicians contacted.

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Objectives: The primary objective was to compare the analgesic efficacy of ultrasound-guided erector spinae plane block (ESPB) with a sham procedure in adult patients presenting with rib fractures to the emergency department (ED).

Methods: A randomized controlled trial was conducted at an academic ED over a 17-month period. Forty-six adults with confirmed rib fractures and numeric rating score (NRS) greater than 4 were randomized to one of two treatment arms: ultrasound-guided ESPB group or placebo (sham procedure).

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Article Synopsis
  • The study investigates the effectiveness of four plagiarism detection tools (iThenticate, Grammarly, Small SEO Tools, and DupliChecker) on AI-generated articles due to rising plagiarism incidents in research.
  • A total of 100 AI-generated articles were analyzed using these tools, revealing significant differences in Overall Similarity Index (OSI), with Grammarly performing the best.
  • Factors such as article length and linguistic complexity influenced detection outcomes, highlighting the importance of choosing the right tool for effective plagiarism detection.
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Myocarditis manifestations in dengue cases: A systematic review and meta-analysis.

J Infect Public Health

November 2023

Department of Clinical Microbiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu 44600, Nepal; Department of Clinical Microbiology, Dr.D.Y Patil Medical College, Hospital and Research Centre, D.Y Patil Vidyapeeth, Pune 411000, India; Department of Public Health Dentistry, Dr. D.Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth, Pune 411018, Maharashtra, India. Electronic address:

Background: Dengue fever is a zoonotic viral infection that raises a global alarm in the tropics and subtropics, with the potentially escalating into newer geographical regions. Severe dengue may be associated with fatal complications such as myocarditis. There is a paucity of available data on the prevalence of dengue-associated myocarditis.

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Article Synopsis
  • Lip, oral, and pharyngeal cancers pose significant global health challenges, making it essential to analyze their burden for effective health policies.
  • The study utilized data from the 2019 Global Burden of Diseases, Injuries, and Risk Factors Study to assess cancer incidence, mortality, and life years lost across 204 countries, linking these to socio-demographic factors.
  • Findings revealed approximately 370,000 cases and 199,000 deaths for lip and oral cavity cancer, and 167,000 cases and 114,000 deaths for other pharyngeal cancers in 2019, with smoking being the leading risk factor for these cancers, especially in low and middle SDI regions.
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Background: There is significant pathogenic and epidemiological overlap between diabetes and obstructive sleep apnea (OSA). This systematic review aimed to ascertain the association between OSA and cardiovascular disease (CVD) in a diabetic population.

Methods: The study protocol was registered with PROSPERO (CRD42023404126).

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Burden of stillbirths among women vaccinated with COVID-19 vaccines: A systematic review and meta-analysis.

Travel Med Infect Dis

August 2023

Tribhuvan University Teaching Hospital, Kathmandu, 46000, Nepal; Department of Microbiology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India; Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, 442001, India. Electronic address:

Objective: To estimate the global burden of stillbirths among pregnant women with the COVID-19 vaccination.

Data Source: In this systematic review and meta-analysis, a literature search was carried out in PubMed, Cochrane and Scopus until February 4, 2023, with language restriction (English).

Study Selection: Title-abstract screening followed by full text review was done independently by two authors, based on the research question, "What is the prevalence of stillbirths among the pregnant women vaccinated with COVID-19 vaccines?"

Data Extraction: Two authors independently extracted the relevant data from every study.

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Exposure to particulate matter less than 2.5 µm in diameter (PM) is a cause of concern in cities and major emission regions of northern India. An intensive field campaign involving the states of Punjab, Haryana and Delhi national capital region (NCR) was conducted in 2022 using 29 Compact and Useful PM Instrument with Gas sensors (CUPI-Gs).

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Intergenic spacer (IGS-1) region sequence-based identification, genotypic analysis, and antifungal susceptibility of clinical Trichosporon species.

Indian J Med Microbiol

November 2023

Department of Medical Microbiology, Postgraduate Institution of Medical Education & Research (PGIMER), Chandigarh, 160012, India. Electronic address:

Objectives: Molecular genotyping of Trichosporon species using intergenic spacer region (IGS-1) sequencing and antifungal drug susceptibility testing of T. asahii clinical isolates from Indian patients.

Materials And Methods: Fifty-five Trichosporon strains were characterized using IGS-1 sequencing from 2006 to 2018 and tested against 5 antifungals using CLSI M27-A3 guidelines.

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Background: Chronic stress, a potential risk factor for cardiac autonomic dysfunction and cardiovascular (CV) risk, is known to induce the onset and exacerbation of chronic spontaneous urticaria (CSU), a psychodermatological disorder. However, data regarding CV risks due to the stress associated with CSU are very limited.

Aims And Objectives: This study aimed at comparing the cardiac sympathovagal balance (SVB), inflammatory markers, perceived stress and quality of sleep in patients with CSU (test group) and normal subjects (control group).

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Introduction: H5N1 is a highly pathogenic avian influenza virus that can infect humans and has an estimated fatality rate of 53%. As shown by the current situation of the COVID-19 pandemic, emerging and re-emerging viruses such as H5N1 have the potential to cause another pandemic. Thus, this study outlined the hub genes and pathways associated with H5N1 infection in humans.

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Aims: Both xanthogranulomatous cholecystitis (XGC) and IgG4-related cholecystitis (IgG4-CC) are rare chronic fibroinflammatory tumefactive diseases of the gallbladder, which cause a strong confusion with resectable malignancy in view of their mass forming tendency with extension into the liver. We aim to study the histopathologic features of xanthogranulomatous cholecystitis with regard to IgG4-related cholecystitis in extended cholecystectomy specimens.

Methods And Results: Sixty cases of extended cholecystectomy with liver wedge resection, diagnosed as XGC on histopathology from January 2018 to December 2021 were retrieved from the archives.

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Article Synopsis
  • The monkeypox virus (MPXV) is causing a global mpox pandemic, prompting a study to evaluate healthcare professionals' knowledge about the disease across 17 Arab countries.
  • A survey revealed that only 13.8% of medical students and doctors had received information about mpox during their education, with a low average knowledge score among participants.
  • With over half of respondents recognizing symptoms of mpox and specialist doctors showing better knowledge, there is an urgent need for enhanced awareness and education among healthcare workers to aid in early detection and prevention efforts.
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Antiplatelet and/or anticoagulant agents (collectively known as antithrombotic agents) are used to reduce the risk of thromboembolic events in patients with conditions such as atrial fibrillation, acute coronary syndrome, recurrent stroke prevention, deep vein thrombosis, hypercoagulable states and endoprostheses. Antithrombotic-associated gastrointestinal (GI) bleeding is an increasing burden due to the growing population of advanced age with multiple comorbidities and the expanding indications for the use of antiplatelet agents and anticoagulants. GI bleeding in antithrombotic users is associated with an increase in short-term and long-term mortality.

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Introduction: Currently, there are no guidelines for the management of B-cell lineage acute lymphoblastic leukemia (B-ALL) from an Indian perspective. The diagnostic workup, monitoring, and treatment of B-ALL vary among different physicians and institutes.

Objective: To develop evidence-based practical consensus recommendations for the management of B-ALL in Indian settings.

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Marburg virus disease in Equatorial Guinea: The need for one health approach.

Travel Med Infect Dis

June 2023

Department of Public Health Dentistry, Dr. D.Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth, Pune, 411018, Maharashtra, India; Tribhuvan University Teaching Hospital, Institute of Medicine, Kathmandu, Nepal; Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India. Electronic address:

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Background: The accurate estimation of the prevalence of mpox-induced ophthalmic lesions will enable health departments to allocate resources more effectively during the ongoing mpox pandemic. The aim of this meta-analysis was to estimate the global prevalence of ophthalmic manifestations in mpox patients.

Methods: A systematic search was carried out in seven databases-Pub Med, Scopus, Web of Science, EMBASE, ProQuest, EBSCOHost, and Cochrane-for studies published on or before 12 December 2022.

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Article Synopsis
  • - The field of neuroanaesthesia has grown rapidly to address new challenges in patient care during neurosurgical and diagnostic procedures, leveraging advanced technology and techniques.
  • - Innovations like intraoperative CT scans, MRI, and minimally invasive methods have transformed vascular neurosurgery, allowing for more complex and precise procedures.
  • - Recent developments in neuroanaesthesia include the use of ketamine, opioid-free techniques, and supportive methods for intraoperative monitoring, alongside an emphasis on awake surgeries to improve patient outcomes.
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Background: Optimal breastfeeding (BF) practices are essential for child survival and proper growth and development. The purpose of this overview is to evaluate the effectiveness of different interventions for promoting and optimizing breastfeeding.

Methods: We included systematic reviews (SRs) [including trials from Low-Income (LICs) and Low Middle-Income countries (LMICs)] that have evaluated the effect of various interventions for promoting and optimizing breastfeeding and excluded non-systematic reviews, and SRs based on observational studies.

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