A RETROSPECTIVE STUDY OF THE MAXILLOFACIAL INJURIES IN TWO EMERGENCY DEPARTMENTS IN TBILISI, GEORGIA.

Maxillofacial injuries are a global problem in our modern society. It can be a major cause of increased morbidity and mortality. Maxillofacial trauma can lead to scar distortion accompanied by emotional and psychological problems.

BRIDGING GAP BETWEEN PRE AND POSTOPERATIVE PROSTATE BIOPSIES: PI RADS CORRELATION WITH FINAL HISTOPATHOLOGICAL DATA.

We aim to define strength of correlation between Prostate Imaging Reporting and Data System (PI RADS) scores of prostate cancer and final histopathological data-postoperative Gleason scores (Gs); apparent diffusion coefficient (ADC) and Gs; to define mean ADC values for each Gleason grade as well. To determine compliance of MRI data in preoperative prostate cancer grading with gold standard-morphological data. 203 consecutive patients suspected for prostate cancer (Pc) on multiparametric MRI, who underwent subsequent preoperative TRUS or MRI/Ultrasound fusion guided biopsies were included to this study prospectively.

Epidemiological features of traumatic brain injuries from a first-level trauma care national medical center in Georgia.

Introduction: Traumatic brain injuries is a significant public health issue in both developed and developing countries. In Georgia, traumatic brain injuries remains one of the leading causes of mortality and disability. Traumatic brain injuries affect families, communities and societies in Georgia and have far-reaching human, social and economic costs, manifested in increased emergency department visits, hospitalizations, disability and deaths.

STUDY OF DRIVER'S ATTITUDES TOWARDS ROAD SAFETY IN GEORGIA.

Introduction: Road traffic injuries are a global public health challenges and a leading cause of death and disability. This study examines the relationships between road traffic accident involvement, driving behaviors, and drivers' attitudes towards traffic safety in Georgia.

Material And Methods: Behavior of 200 Georgian drivers were reported using a self-administered questionnaire.

The role of CD180 in hematological malignancies and inflammatory disorders.

Toll-like receptors play a significant role in the innate immune system and are also involved in the pathophysiology of many different diseases. Over the past 35 years, there have been a growing number of publications exploring the role of the orphan toll-like receptor, CD180. We therefore set out to provide a narrative review of the current evidence surrounding CD180 in both health and disease.

SOCIO-ECONOMIC FEATURES OF SEXUALLY TRANSMITTED INFECTIONS AMONG MSM IN GEORGIA.

The aim of our study was to investigate correlation between socio-Economic conditions and prevalence of Sexually Transmitted Infections among gay individuals (men who have sex with men, MSM) in Georgia. The study was conducted in 5 main cities in different regions of Georgia (Tbilisi, Batumi, Kutaisi, Zugdidi, and Telavi). During 2015-2019, social workers, LGBT community and non-governmental organizations (NGOs), conducted screening of MSM for STI, which was achieved by disseminating required information through electronic and print media, resulting in maximum involvement of MSM in screening programs for STI disseminating.

Synthesis, Characterization, and In Vitro Cytotoxicity Evaluation of Doxorubicin-Loaded Magnetite Nanoparticles on Triple-Negative Breast Cancer Cell Lines.

In this study, we investigated the cytotoxicity of doxorubicin (DOX)-loaded magnetic nanofluids on 4T1 mouse tumor epithelial cells and MDA-MB-468 human triple-negative breast cancer (TNBC) cells. Superparamagnetic iron oxide nanoparticles were synthesized using sonochemical coprecipitation by applying electrohydraulic discharge treatment (EHD) in an automated chemical reactor, modified with citric acid and loaded with DOX. The resulting magnetic nanofluids exhibited strong magnetic properties and maintained sedimentation stability in physiological pH conditions.

Human Life Course as Constructive Migration.

In this paper, I discuss the systemic features of the life-span development approach which was initially elaborated by Baltes (1989) and more recently considered by Greve (Integrative Psychological and Behavioral Science, 1-21, 2023). I argue that the life-span development approach should recognize the agentivity of people as they not only passively react to changes inside and around themselves but rather imaginatively co-construct their selves (and, their environment) through aging. The irreversibility of human development is highlighted in this paper simultaneously with the recognition of the significance of past phenomenological experiences for self-construction.

A global survey on the attitudes of neurologists and psychiatrists about functional/psychogenic/dissociative/nonepileptic-seizures/attacks, in the search of its name.

Purpose: We conducted an observational study to investigate the opinions of neurologists and psychiatrists all around the world who are taking care of patients with seizures [epilepsy and functional seizures (FS)].

Methods: Practicing neurologists and psychiatrists from around the world were invited to participate in an online survey. On 29th September 2022, an e-mail including a questionnaire was sent to the members of the International Research in Epilepsy (IR-Epil) Consortium.

Impact of the Angiotensin-Converting Enzyme (ACE) Inhibitors on the Course of the Acute Respiratory Distress Syndrome (ARDS) Developed During COVID-19 and Other Severe Respiratory Infections Under Hyperferritinemia Conditions: A Cohort Study.

Background: Angiotensin-converting enzyme 2 (ACE2) is not only the entry route of SARS-CoV-2 infection but also triggers a major mechanism of COVID-19 aggravation by promoting a hyperinflammatory state, leading to lung injury, hematological and immunological dysregulation. The impact of ACE2 inhibitors on the course of COVID-19 is still unclear. The effect of ACE2 inhibitors on the course of acute respiratory distress syndrome (ARDS) during COVID-19 and other severe respiratory infections in conditions of hyperferritinemia (HF) was investigated.

Language phenotypes in children with autism spectrum disorder, expressive language disorder, and typical language development.

The aim of this study was to compare language abilities in 4-6-year-old Georgian-speaking children with typical language development (TLD), expressive language disorder (ELD), and autism spectrum disorder (ASD). Language linguistic components, such as phonology, semantics, syntax, morphology, and pragmatics, were examined along with verbal behavior types like "mand," "tact," "echoic," and "intraverbal." Our sample comprised 148 children, with a gender distribution of 50 girls and 98 boys.

The Potential Impact of E-cigarettes on the Life-Years Lost from Conventional Smoking in the Russian Federation.

Unlabelled: This study analyses the potential impact of e-cigarettes on the death toll of cigarette smoking in the Russian Federation by working under a variety of assumptions pertaining to how much vaping might affect smoking cessation and initiation, and its adverse impacts on health in comparison to conventional smoking. Within this study, each combination of these assumptions generates a single vaping scenario (210 in total). A dynamic population simulation model, specifically for the Russian Federation, that is tailoured to tobacco control policy analysis, is built for estimation purposes.

Characterization of a Bacteriophage GEC_vB_Bfr_UZM3 Active against .

is a commensal gut bacterium that is associated with a number of blood and tissue infections. It has not yet been recognized as one of the drug-resistant human pathogens, but cases of the refractory infections, caused by strains that are not susceptible to the common antibiotic regimes established for have been more frequently reported. Bacteriophages (phages) were found to be a successful antibacterial alternative to antibiotic therapy in many cases of multidrug-resistant (MDR) bacterial infections.

Study of Epidemiological Characteristics of Fatal Injuries Using Death Registry Data in Georgia.

Objective: This study aimed to evaluate epidemiological aspects of fatal injuries in Georgia.

Methods: This was a retrospective, descriptive study that included all traumatic injury deaths in Georgia from January 1 to December 31, 2018. The National Center for Disease Control and Public Health of Georgia's Electronic Death Register database was utilized in this research.

Tietze Syndrome as a Cause of Chest Pain in the Post-COVID-19 Period.

Tietze syndrome is a rare disease. It is mainly characterized by chest pain caused by a unilateral and monoarticular lesion of the second-fifth costal joints. Tietze syndrome is one of the potential complications in the post-COVID-19 period.

HIV-Related Atherosclerosis: State-of-the-Art-Review.

The infection caused by the Human Immunodeficiency Virus (HIV) has spread rapidly across the globe, assuming the characteristics of an epidemic in some regions. Thanks to the introduction of antiretroviral therapy into routine clinical practice, there was a considerable breakthrough in the treatment of HIV, that is now HIV is potentially well-controlled even in low-income countries. To date, HIV infection has moved from the group of life-threatening conditions to the group of chronic and well controlled ones and the quality of life and life expectancy of HIV people, with an undetectable viral load is closer to that of an HIV people.

FALL RELATED GERIATRIC TRAUMA TRENDS IN GEORGIA.

The main of the study was to examine the overall trends and epidemiologic characteristics of fall-related hospitalizations in the population aged 65 years and above in Georgia. For this observational study Hospital database was used. Data were collected from all hospitalized patients aged 65 years and above during 2015-2021 in the country.

QUALITY OF LIFE AND DISEASE COPING STRATEGIES IN PATIENTS WITH ROSACEA.

Rosacea is a chronic, inflammatory skin disorder that adversely affects patients' life quality. The aim of the study was to evaluate the quality of life (QoL) and to find the connection between QoL and coping strategies in the patients suffering from rosacea. A total of 138 patients, aged from 22 to 80, took part in this research with the first-time confirmed diagnosis of rosacea.

Improved professional practices in social services through Emotional Labor strategies.

The present study provides an analysis of Emotional Labor (EL) and its consequences for professional social work practitioners in Georgia. This mixed-methods study comprised two stages. First, a qualitative study was conducted to determine the organizational characteristics defined by social work practitioners ( = 70).

Adaptive Mechanisms of DCB 2-1 Metallophilicity.

The dose-dependent effects of single metals (Zn, Ni, and Cu) and their combinations at steady time-actions on the cell viability of the bacteria DCB 2-1, isolated from a radionuclide-contaminated area, have been estimated. The accumulation of metals by DCB 2-1 in single and multi-metal systems was assessed using the inductively coupled plasma atomic emission spectroscopy. To estimate the response of the bacteria's antioxidant defense system, doses of 20 and 50 mg/L of single studied metals and 20 mg/L of each metal in their combinations (non-toxic doses, determined by the colony-forming viability assay) were used.

Evaluation of barriers to cervical cancer screening in Georgia.

Objectives: The Cervical Cancer (CC) Screening Programme in Georgia provides insufficient coverage of the target population. The aim of the study is to identify the barriers to cervical cancer screening for women in Georgia in order to plan and implement adequate measures to increase the screening effectiveness.

Methods: The study is based on the results of a survey of 582 women aged 25-60 years (mean age 42.

Study of blood rheological parameters and NO in coronary artery disease patients with and without collaterals.

Background: In coronary artery disease (CAD), an alternative way of improvement of blood circulation in the ischemic area of the myocardium is coronary collateral circulation. Our study aimed to investigate the rheological parameters of blood and nitric oxide (NO) content in patients with various degrees of collateral development and the likelihood of the influence of blood fluidity on collateral angiogenesis.

Methods: We studied patients with stable CAD who underwent elective coronary angiography and a control group with the same mean age.

Annotated checklist of Georgian oribatid mites-II.

The checklist of oribatid mites from Georgia is updated using sampling data from more than 230 locations during field works conducted between 2016 and 2022. We report 32 species of oribatid mites, sixteen of them were collected between 2017 and 2019, six were missing in Checklist I, while eleven species are new records for the country. The genus Ameronothrus was found in Georgia for the first time, but could not be identified to species level.