Diabetes and atherosclerosis as immune-inflammatory disorders: options for reversal of disease processes.

Hypothesis is presented to suggest that the present epidemic of DM and ACVD in Asian indians and possibly in other communities is iatrogenic resulting from what may be called modern malnutrition due to increased intake of total and n-6 fats and decreased intake of n-3 fat and antioxidants. Such a diet induces oxidative stress and activates the immune system. Imbalance between n-6 and n-3 fats result in inappropriate immune response.

Percutaneous transluminal coronary angioplasty in totally occluded arteries.

Out of 321 consecutive cases of Percutaneous Transluminal Coronary Angioplasty (PTCA), 28 (8.7%) patients underwent PTCA for nonacute total occlusion with no visible antegrade flow. All patients had evidence of reversible ischaemia in the territory of totally occluded artery.

Renal parameters during infancy.

In a prospective study we estimated common renal parameters in 48 full term normal neonates, of which 15 were also tested at 6 months and 12 months of age. The mean levels of serum creatinine, were high at birth (0.73 mg/dl) but normal for age at 6 and 12 months; uric acid followed a similar trend.

Use of combined myeloperoxidase and immunogold technique in hybrid leukemia: a case report.

A case of hybrid leukemia is presented. A 30-year-old man had two blast cell populations with bone marrow. The majority of the blast cells had B-lymphoid markers on their surfaces and a small number of cells had both lymphoid markers and penoxidase activity on the same cell.

Anaerobic threshold as a measure of physical work capacity.

Fifty healthy subjects underwent incremental exercise on a treadmill. Anaerobic threshold (AT) and maximum oxygen consumed in litres per minute (VO2 max) were measured. VO2 max (mean +/- SD) in males and females was 2.

Isolation of Helicobacter pylori from dental plaques in healthy volunteers.

The presence of Helicobacter pylori (H pylori) was looked for in dental plaques of 40 healthy volunteers by CLO test, culture and smear stained with Warthin-Starry stain. H pylori was found to be present in the dental plaques of all 40 volunteers. The dental plaque is an important reservoir of H pylori.

Multiple sclerosis is prevalent in the Zoroastrians (Parsis) of India.

Using Schumacher's classification, we determined the prevalence rate of clinically definite multiple sclerosis (MS) in the distinct but tiny Zoroastrian (largely Parsi) community in the adjacent cities of Bombay (latitude, 18.55 degrees) and Poona (Pune). On prevalence day, 16 clinically definite cases of MS were counted, 14 in Bombay and 2 in Poona, from a total Zoroastrian population of 50,053 and 3,399, respectively.

Serum angiotensin converting enzyme in the diagnosis of pulmonary sarcoidosis.

Serum angiotensin converting enzyme (SACE) was estimated in 25 normal healthy subjects mean (15.62 +/- 6.5 mU/mL/37 degrees C), 26 patients with sarcoidosis (32.

Disseminated cysticercosis. New observations, including CT scan findings and experience with treatment by praziquantel.

Although the symptom complex of disseminated cysticercosis has been well recognized for over half a century, it is not clearly included in recent disease classifications. Three such patients are described whose main features were uncontrolled seizures, progressive dementia, behaviour disorder, muscular pseudohypertrophy, and a relative paucity of localizing neurological signs or signs of raised intracranial pressure. Radiographic calcification in muscles was not seen.

Association of HLA-B12 with multiple sclerosis in India.

In Indian patients with Multiple Sclerosis it was observed, upon testing for serum determinable histocompatibility antigens, that HLA-B12 antigen was present in excess (77.7%), in comparison with normal controls (13.8%).