942 results match your criteria: "Jaslok & Bhatia Hospital[Affiliation]"

Global conflicts and humanitarian crises have resulted in an unprecedented number of refugees and migrants. This challenges the limited resources of health care systems and jeopardizes the availability of transplant care for these deserving migrants and refugees. This was the basis for a workshop held during the Congress of the Transplantation Society (Buenos Aires, 2022).

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Article Synopsis
  • * The timeline of infections post-transplant indicates that bacterial infections dominate initially, with viral and fungal infections becoming more prevalent later, and opportunistic infections usually occurring within the first 6 months.
  • * To effectively manage infection risks, it is essential to consider factors like time since transplant, patient history, and local infection trends, leading to a need for tailored regional guidelines for screening and prevention.
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Background: The role of deep brain stimulation in the treatment of dystonia has been widely documented. However, there is limited literature on the outcome of lesioning surgery in unilateral dystonia.

Objective: We restrospectively reviewed our cases of focal and hemidystonia undergoing unilateral Pallidotomy at our institute to evaluate the short-term and long-term outcome.

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Objective: To investigate the adverse effects of phthalate-induced ovarian toxicity on the ovarian reserve and ovarian function. To assess whether the accumulation of higher levels of selected phthalate metabolites in the follicular fluid (FF) of Indian women undergoing intracytoplasmic sperm injection (ICSI) was associated with a decline in their antral follicle count (AFC) and/or serum antimüllerian hormone (AMH) levels, suggesting a negative impact on the ovarian reserve. To evaluate the effects of follicular phthalate metabolites on peak serum estradiol (E) levels and the total number of oocytes and mature metaphase II (MII) stage oocytes retrieved to assess the impact of phthalate toxicity on ovarian function.

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Purpose: The treatment outcomes of adolescent and young adult (AYA) cancers have improved with advanced oncology care. Hence, fertility preservation (FP) and post-therapy pregnancies (PTPs) become vital issues.

Materials And Methods: An online survey link with 17 questions regarding oncofertility and PTPs was circulated among oncologists to assess the knowledge, understand the oncofertility care patterns, and seek suggestions to improve oncofertility services.

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Intraoperative bleeding poses a substantial challenge, particularly in neuro-spine surgeries leading to complications such as hematomas, infections, and hemodynamic instability. Despite their proven efficacy, use of topical hemostatic agents (THAs) lacks comprehensive published literature and guidelines particularly in the Indian setting. The present study provides the first-ever Indian expert panel recommendations for effective adjunct THA use in different intraoperative bleeding sites and situations in neuro-spine surgeries.

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Added Value of Contrast-enhanced US for Evaluation of Female Pelvic Disease.

Radiographics

February 2024

From the Department of Radiology, University of North Carolina at Chapel Hill, 2021 Old Clinic Bldg, Chapel Hill, NC 27599 (K.O.); Department of Radiology, University of Toronto, Toronto, Ontario, Canada (X.L.); Department of Radiology, University of British Columbia, Vancouver, British Columbia, Canada (Parisa Khoshpouri); Department of Radiology, University of Washington, Seattle, WA (Pegah Khoshpouri); Department of Radiology, Yale University, New Haven, CT (L.M.S.); Department of Radiology, University of Kentucky, Lexington, KY (A.K.); Department of Radiology, Jaslok Hospital, Mumbai, India (R.N.C.); and Department of Radiology, Vanderbilt University Medical Center, Nashville, TN (M.M.).

Since the first application of contrast-enhanced US (CEUS) in the late 1960s, the use of US contrast agents has grown tremendously, and this examination has proved to be a valuable adjunct to diagnostic US for detection and characterization of disease. Also, CEUS has emerged as an excellent option for evaluation of indeterminate lesions that require additional imaging, given its excellent safety profile, including that in patients with end-stage renal disease or allergies to contrast material who are unable to undergo contrast-enhanced CT or MRI. US traditionally has been considered the imaging modality of choice for evaluation of the female pelvis, followed by MRI and rarely fluoroscopy, CT, PET, or angiography.

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Pre-implantation genetic testing (PGT) is a vital tool in preventing chromosomal aneuploidies and other genetic disorders including those that are monogenic in origin. It is performed on embryos created by intracytoplasmic sperm injection (ICSI). Genetic counseling in the area of assisted reproductive technology (ART) has also evolved along with PGT and is considered an essential and integral part of Reproductive Medicine.

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Pancreatitis is a very rare complication of methimazole and carbimazole therapy. We describe a case of possible carbimazole-associated pancreatitis. A 41-year-old Asian man (with no comorbidities) reported to the hospital with atrial fibrillation and a fast ventricular rate.

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Objective: This study aimed to propose a systematic approach for managing thick-skinned rhinoplasty patients.

Methods: A retrospective review of the treatment of 26 thick-skinned patients with aesthetic and/or functional problems over a period of three years from January 2018 to January 2021 with a follow up for one year. A presurgical evaluation of skin was carried out initially.

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Solitary fibrous tumor (SFT) of the central nervous system (previously called hemangiopericytoma) is a rare mesenchymal tumor. Malignant SFT has a tendency to recur after surgery and can metastasize to distant organs. Treatment options for metastatic disease are limited.

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Semen proteomics reveals alterations in fertility-related proteins post-recovery from COVID-19.

Front Physiol

November 2023

Department of Assisted Reproduction and Genetics, Jaslok-FertilTree International Centre, Jaslok Hospital and Research Centre, Mumbai, India.

Changes to sperm quality and decline in reproductive function have been reported in COVID-19-recovered males. Further, the emergence of SARS-CoV-2 variants has caused the resurgences of COVID-19 cases globally during the last 2 years. These variants show increased infectivity and transmission along with immune escape mechanisms, which threaten the already burdened healthcare system.

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Introduction: The diverse subtypes of thyroid carcinoma have distinct clinical outcomes despite a comparable spectrum of underlying genetic alterations. Beyond genetic alterations, sparse efforts have been made to characterize the microbes associated with thyroid cancer. In this study, we examine the microbial profile of thyroid cancer.

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Article Synopsis
  • Recent research has pinpointed over 20 genes linked to Parkinson's disease (PD), yet most studies have concentrated on European populations, leaving a gap in understanding PD genetics in other regions, particularly South Asia.
  • The study recruited 674 PD patients, mostly under 50 years old, and 1,376 control subjects from India to investigate genetic risk factors, finding significant results in the SNCA region that aligns with European PD studies.
  • Notably, cases with specific gene mutations had lower overall genetic risk scores and the research identifies a link to the BSN gene, previously associated with neurodegenerative diseases, marking the largest genetic study of PD in South Asia and highlighting the need for further research in this area.
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Unmet Needs in Geriatric Oncology.

South Asian J Cancer

April 2023

Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Nikhil PathiIndia's population is aging, with the number of people aged 60 and over projected to reach 340 million by 2050. This is expected to lead to an increase in the number of older adults with cancer. Geriatric oncology is a rapidly growing field in India that is facing several challenges.

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Management of the neck in oral cavity squamous carcinoma is debatable. There is controversy regarding role of SND in single node positive neck in oral SCC. The aim of this study was to determine the efficacy of selective neck dissection (SND) for cN1 neck in patients with oral cancer.

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ARCH Is Bringing Asia Closer to the Rest of the World.

Brain Sci

October 2023

Asian Regional Consortium for Headache (ARCH), Jaslok and Lilavati Hospitals, Mumbai 400050, India.

As the immediate Past President (KR) of Asian Regional Consortium For Headache (ARCH) and the newly appointed President (TW) of ARCH, we are pleased to share our thoughts with the readers of MDPI [...

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Purpose: Assess the utility of a hands-on cadaver workshop for teaching abdominal wall reconstruction (AWR) using components separation technique.

Methods: Over a year, from June 2022 to July 2023, 112 surgeons participated in seven training courses focused on the eTEP technique for inguinal and ventral hernias. The workshops covered theoretical learning sessions followed by hands-on training using frozen human cadavers.

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The current status of geriatric oncology in India.

Ecancermedicalscience

August 2023

Department of Medical Oncology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai 400012, India.

Geriatric oncology in India is relatively new. The number of older persons with cancer is increasing exponentially; at our institution, 34% of patients registered are 60 years and over. Apart from the Tata Memorial Hospital in Mumbai, there are currently no other Indian centers that have a dedicated geriatric oncology unit.

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