Effects of antiviral therapy for hepatitis C following treatment of hepatocellular carcinoma: survey findings of the Japanese Red Cross Liver Study Group.

Aim: To investigate, in a large number of cases at multiple institutions, the effects and limitations of antiviral therapy for hepatitis C following treatment of hepatocellular carcinoma (HCC) in clinical practice.

Methods: Retrospective analysis was performed of 112 patients who had received interferon (IFN) for treating hepatitis C following treatment of HCC and were registered with the Japanese Red Cross Liver Study Group. Factors that may influence recurrence and survival rates were investigated.

[Surgical treatment for pulmonary mycosis].

Although most human mycosis develops in immunocompromised patients as an opportunistic infection, its frequency will be influenced by historical changes in diseases and by progress in medical technology. An example of local occurrence is pulmonary aspergilloma in an open negative cavity, and a systemic example is the onset of invasive pulmonary aspergillosis in neutropenic patients with hematologic malignancies. Surgical candidates for mycotic lung disease are usually patients who do not improve with medical treatment The author also stresses the prophylactic indications for prevention of unexpected impairment due to mycotic lung disease.

Advanced renal cell carcinoma in which a combination of IFN-alpha and meloxicam was thought to be effective.

An 83-year-old man with left renal cell carcinoma (RCC; pT4N0M0) was treated with postoperative combined subcutaneous injection therapy of alpha interferon (IFN-alpha) and IFN gamma-1a (IFN-gamma-1a). Metastasis to the pleura occurred 3 months after surgery. The metastatic lesion grew while the treatment was changed to intramuscular injection of IFN-alpha-2b due to the presence of severe general malaise, which seemed to be caused by IFN-alpha and IFN-gamma therapy.

Pathological evaluation of the rat endometriosis model.

Objective: To observe in detail the morphology of experimental rat endometriosis, specifically in peritoneum adjacent to uterine transplants attached via autotransplantation.

Design: Light and electron microscopic study.

Setting: Tochigi Institute of Clinical Pathology, Japan.

[Change of cardiovascular risk factors after eradication therapy of Helicobacter pylori].

We studied the effect of eradication of Helicobacter pylori (H.P.) on several cardiovascular risk factors in patients with peptic ulcer disease.