1 results match your criteria: "JapanFaculty of Science and EngineeringGunma University[Affiliation]"
Automated image analysis of a glomerular injury marker desmin in spontaneously diabetic Torii rats treated with losartan.
J Endocrinol
July 2014
Safety Research LaboratoriesAdvanced Medical Research LaboratoriesResearch Division, Mitsubishi Tanabe Pharma Corporation, Toda-shi, Saitama 335-8505, JapanFaculty of Science and EngineeringGunma University, Kiryu-shi, Gunma 376-8515, JapanPharmacology Research Laboratories IIResearch Division, Mitsubishi Tanabe Pharma Corporation, Toda-shi, Saitama 335-8505, Japan.
Diabetic nephropathy is a major complication in diabetes and a leading cause of end-stage renal failure. Glomerular podocytes are functionally and structurally injured early in diabetic nephropathy. A non-obese type 2 diabetes model, the spontaneously diabetic Torii (SDT) rat, is of increasing preclinical interest because of its pathophysiological similarities to human type 2 diabetic complications including diabetic nephropathy.
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