93 results match your criteria: "Japan Community Health care Organization Tokyo Shinjuku Medical Center[Affiliation]"

Long-term follow-up study of Kudo Type-5 elbow prosthesis in patients with rheumatoid arthritis: minimum 10-year clinical outcomes.

J Shoulder Elbow Surg

December 2024

Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. Electronic address:

Objectives: Rheumatoid arthritis often leads to debilitating damage in the elbow joint, which may require total elbow arthroplasty (TEA). The Kudo TEA is one of the unlinked type prostheses with reportedly favorable outcomes. However, there is limited information available regarding its long-term performance.

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Risk Factors and Prevalence of Sleep Disturbance in Degenerative Cervical Myelopathy.

World Neurosurg

December 2024

Department of Orthopaedic Surgery and Spinal Surgery, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan; University of Tokyo Spine Group (UTSG), 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.

Background: Sleep disturbances, especially those lasting more than one hour, are under-researched in patients with degenerative cervical myelopathy (DCM). This study aims to investigate the prevalence and risk factors for such disturbances in DCM patients undergoing decompression surgery and to identify factors contributing to poor postoperative improvement.

Methods: A multicenter retrospective observational study was conducted on consecutive patients diagnosed with DCM who underwent cervical decompression surgery between April 2018 and August 2022.

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Article Synopsis
  • The study compares microendoscopic laminectomy (MEL) and open laminectomy in patients with multi-level lumbar spinal canal stenosis (LSCS), focusing on patient outcomes and complications.
  • It involved 882 patients from eight spine centers, analyzing factors like blood loss, operation time, complications, and patient-reported outcomes over a one-year follow-up.
  • Results showed that MEL had lower blood loss and a significantly reduced rate of surgical site infections compared to open laminectomy, with comparable complication rates overall.
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Correlation between severity of preoperative low back pain and postoperative outcomes in lumbar disc herniation surgery: a retrospective cohort study.

Spine J

November 2024

Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan; University of Tokyo Spine Group (UTSG), 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan. Electronic address:

Background Context: Low back pain (LBP) frequently occurs in patients with lumbar disc herniation (LDH), however the extent to which discectomy ameliorates it and how preoperative LBP influences postoperative outcomes remains unclear.

Purpose: To evaluate the improvement in LBP and its impact on postoperative patient-reported outcome measures (PROMs).

Study Design/setting: Multicenter retrospective observational study.

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  • Incidental dural tears (DTs) during cervical spine surgery are a serious concern, yet their effects on patient-reported outcomes (PROs) one year post-surgery are not well understood.
  • The study investigated patients who had elective cervical spine surgeries, examining pre- and postoperative PROs in relation to the occurrence of DTs, identifying complications and differences between patients with and without DTs.
  • Results showed that out of 2,704 patients, 3.6% had DTs, leading to higher rates of complications and more severe neck and pain outcomes in those affected compared to those without DTs.
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  • A 31-year-old woman experienced a sudden headache and altered consciousness, leading to the discovery of a left acute subdural hematoma and a small aneurysm on her left distal posterior cerebral artery, which was treated with coil embolization.
  • Two weeks later, she developed complete left hemiplegia due to an occluded right middle cerebral artery, requiring a mechanical thrombectomy that successfully restored blood flow.
  • Ultimately, she was diagnosed with infective endocarditis after positive blood cultures revealed bacterial presence and a TEE identified vegetation on the mitral valve; she was treated with penicillin and discharged without neurological deficits.
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  • Cervical radiculopathy impacts finger movement and dexterity, and a study analyzed 359 patients who underwent surgery for this condition, comparing those with C8 radiculopathy to those with C5-7 radiculopathy.
  • The study found that while arm pain decreased significantly after surgery, patients with C8 radiculopathy experienced worse post-surgery neck disability index (NDI) scores and higher levels of upper back pain and numbness compared to the C5-7 group.
  • Overall, the findings suggest that despite relief from arm pain after surgery, C8 radiculopathy patients had a less favorable clinical outcome compared to those with C5-7 radiculopathy.
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Introduction: The association between postoperative patient-reported outcomes (PROs) and patient satisfaction remains poorly defined in patients undergoing surgery for thoracic myelopathy. This study aimed to investigate PROs and patient satisfaction following surgical intervention for thoracic myelopathy.

Methods: A prospective cohort of 133 patients who underwent surgery for thoracic myelopathy at 13 hospitals between April 2017 and August 2021 was enrolled.

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Symptomatic neuroma represents a debilitating complication after major limb amputation. The regenerative peripheral nerve interface (RPNI) has emerged as a reproducible and practical surgery aimed at mitigating the formation of painful neuroma. Although previous animal studies revealed axonal sprouting, elongation, and synaptogenesis of proximal nerve stump within the muscle graft in RPNI, there is a lack of reports confirming these physiological reactions at the histopathological level in human samples.

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Purpose: Adult spinal deformity (ASD) is associated with a combination of back and leg pain of various intensities. The objective of the present study was to investigate the diverse reaction of pain profiles following ASD surgery as well as post-operative patient satisfaction.

Methods: Multicenter surveillance collected data for patients ≥ 19 years old who underwent primary thoracolumbar fusion surgery at > 5 spinal levels for ASD.

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Article Synopsis
  • The CLOT-COVID Study analyzed 2894 hospitalized patients with COVID-19, focusing on 1738 patients with mild cases who didn’t need oxygen at admission.
  • Patients were split into two groups: those receiving prophylactic anticoagulation (326 patients) and those who were not (1412 patients).
  • Results showed that those on anticoagulation had higher severity levels during hospitalization and a slightly higher incidence of thrombosis, suggesting that routine use may not be beneficial for all stable patients.
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  • Ependymomas are diverse tumors with specific types based on where they occur and their molecular characteristics, with spinal ependymomas (SP-EPN) being the most common type found in the spinal cord of both children and adults.
  • Research revealed limited molecular data on SP-EPN, with known genetic changes including losses on chromosome 22q and mutations in NF2, but this study aimed to fill the gaps by analyzing transcriptomic, epigenetic, genetic, and clinical data from a large cohort.
  • The study identified two subtypes of SP-EPN: subtype A, associated with known NF2 mutations and more severe disease, and subtype B, characterized by different genetic alterations and more stable NF2 expression, helping to
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Study Design: Retrospective cohort study.

Objective: The aim of the present study is to investigate the coexisting lower back pain (LBP) in patients with cervical myelopathy and to evaluate changes in LBP after cervical spine surgery.

Summary Of Background Data: Only a few studies with a small number of participants have evaluated the association between cervical myelopathy surgery and postoperative improvement in LBP.

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Comparative Analysis of Microendoscopic and Open Laminectomy for Single-Level Lumbar Spinal Stenosis at L1-L2 or L2-L3.

World Neurosurg

March 2024

Department of Orthopaedic Surgery and Spinal Surgery, The University of Tokyo, Bunkyo City, Tokyo, Japan; University of Tokyo Spine Group (UTSG), Bunkyo City, Tokyo, Japan. Electronic address:

Background: Several reports have highlighted comparable surgical outcomes between microendoscopic laminectomy (MEL) and open laminectomy (open) for lumbar spinal stenosis. However, the unilateral approach in MEL may present challenges for the upper lumbar levels, where facet joints are located deeper inside. Our objective was to compare surgical outcomes and radiographic evaluations for single-level decompression cases at L1-L2 or L2-L3 between MEL and open laminectomy.

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Objectives: To investigate the effect of the COVID-19 pandemic on surgical volume and outcomes in spine surgery.

Design: A retrospective cohort study using prospectively collected data.

Setting And Participants: A total of 9935 patients who underwent spine surgery between January 2019 and December 2021 at eight high-volume spine centres in the Greater Tokyo metropolitan area were included.

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Does surgical site infection affect patient-reported outcomes after spinal surgery? A multicenter cohort study.

J Orthop Sci

November 2024

Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo 113-8655, Japan; University of Tokyo Spine Group (UTSG), 7-3-1, Hongo, Bunkyo-Ku, Tokyo 113-8655, Japan. Electronic address:

Background: Surgical site infections are common in spinal surgeries. It is uncertain whether outcomes in spine surgery patients with vs. without surgical site infection are equivalent.

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Free-flap volume correlates with body mass index in patients with tongue squamous cell carcinoma.

Laryngoscope Investig Otolaryngol

October 2023

Division of Gerontology and Gerodontology Department of Dysphagia Rehabilitation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University Tokyo Japan.

Objectives: This study aimed to investigate the relationship between postoperative reconstructed tongue flap volume (RTFV) and body mass index (BMI) and identify factors affecting the flap volume in patients with tongue squamous cell carcinoma.

Methods: Thirty-two patients were evaluated for RTFV from computed tomography images and BMI. The first and second evaluations were done at 6 months and 1.

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The aim of this retrospective study was to identify clinical predictors of early biochemical recurrence (BCR) in patients with high-risk prostate cancer (PCa) treated with carbon-ion radiotherapy (CIRT) and androgen deprivation therapy (ADT). A total of 670 high-risk PCa patients treated with CIRT and ADT were included in the study. Early BCR was defined as recurrence occurring during adjuvant ADT after CIRT or within 2 years after completion of ADT.

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Background: Oral health management involving dental professionals in a multidisciplinary Nutritional Support Team (NST) is effective collaborative care. However, the indicators for the triage of oral health management requirements and selection of oral healthcare providers remain unclear.

Objective: This cross-sectional study included inpatients with malnutrition and aimed to investigate the factors associated with determining the need for oral health management involving dental professionals and selecting primary oral healthcare providers when needed.

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This prospective, multicentre, interventional study evaluated the efficacy of a modified treat-and-extend (mTAE) aflibercept regimen as personalized therapy for macular oedema (MO) due to central retinal vein occlusion (CRVO). Fifty eyes were studied from 50 patients who were enrolled between November 2016 and July 2019. All patients received intravitreal aflibercept (IVA) injections on an mTAE regimen for 24 months.

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Study Design: Retrospective cohort study using prospectively collected registry data.

Objective: The purpose of this study is to evaluate health-related quality of life (HRQOL) and postoperative satisfaction in patients with different histotypes of benign extramedullary spinal tumors (ESTs).

Background: Little is known about how different histotypes influence HRQOL and postoperative satisfaction in EST patients.

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This study aimed to investigate the clinical features of arterial thrombosis and venous thromboembolism (VTE) in coronavirus disease 2019 (COVID-19). The CLOT-COVID Study was a retrospective, multicenter cohort study that enrolled 2,894 consecutively hospitalized patients with COVID-19 among 16 centers in Japan from April 2021 to September 2021. We compared the clinical features of arterial thrombosis and VTE.

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Impact of body mass index on outcomes after lumbar spine surgery.

Sci Rep

May 2023

Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.

The impact of body mass index (BMI) on outcomes after lumbar spine surgery is currently unknown. Previous studies have reported conflicting evidence for patients with high BMI, while little research has been conducted on outcomes for underweight patients. This study aims to examine the impact of BMI on outcomes after lumbar spine surgery.

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Primary adenoid cystic carcinoma (ACC) of the upper anterior mediastinum is rarely encountered in clinical practice, and no standard treatment has been established. We performed palliative radiotherapy to improve airway narrowing in a patient with primary ACC of the mediastinum who presented with respiratory distress as their main complaint. As a result of radiotherapy, the ACC was reduced in size, the narrowed airway was opened due to compression by the ACC, and the patient's general condition improved.

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Article Synopsis
  • The study investigates the association between thrombosis and clinical outcomes in hospitalized COVID-19 patients in Japan, using data from the CLOT-COVID study.
  • Patients with thrombosis (55 individuals) experienced significantly higher mortality (23.6% vs. 5.1%) and major bleeding events (23.6% vs. 1.6%) compared to those without thrombosis (2839 individuals).
  • Independent risk factors for thrombosis included being male, having elevated D-dimer levels on admission, and severe COVID-19 status, which could help guide treatment decisions for these patients.
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