The Deep Learning-Crop Platform (DL-CRoP): For Species-Level Identification and Nutrient Status of Agricultural Crops.

Precise and timely detection of a crop's nutrient requirement will play a crucial role in assuring optimum plant growth and crop yield. The present study introduces a reliable deep learning platform called "Deep Learning-Crop Platform" (DL-CRoP) for the identification of some commercially grown plants and their nutrient requirements using leaf, stem, and root images using a convolutional neural network (CNN). It extracts intrinsic feature patterns through hierarchical mapping and provides remarkable outcomes in identification tasks.

Repurposing of USFDA-approved drugs to identify leads for inhibition of acetylcholinesterase enzyme: a plausible utility as an anti-Alzheimer agent.

In the quest to identify new anti-Alzheimer agents, we employed drug repositioning or drug repositioning techniques on approved USFDA small molecules. Herein, we report the structure-based virtual screening (SBVS) of 1880 USFDA-approved drugs. The -based identification was followed by calculating Prime MMGB-SA binding energy and molecular dynamics simulation studies.

Flourishing Among Elderly Population: The Role of Social Support and Gratitude.

This paper sets out a framework for exploring flourishing in older age through the lens of social support and gratitude. Flourishing is a relatively new concept in positive psychology. Social support and gratitude are as potential predictors of flourishing among older individuals that considers hedonic and eudaimonic aspects of well-being.

Exploring novel SNPs and candidate genes associated with seed allometry in L.

Unlabelled: Seed size is an important agronomic trait that indicates seed quality. In legumes, pods with equal and larger seeds remain the first preference of farmers and consumers. Genetic understanding related to seed size including seed allometric traits has been limited in the case of peas.

Insights into molecular characterization of NOD1-RIPK interaction and transcriptional modulation in response to LPS in spotted snakehead, Channa punctata (Bloch, 1793).

NOD1, plays a pivotal role in immune responses against bacterial as well as viral invasions. While the downstream signaling pathway of NOD1 is well understood in mammals, its characterization in lower vertebrates remains elusive. In present study, an effort was made to identify and characterize downstream signaling cascade of NOD1 in response to LPS, a potential ligand of NOD1 in teleosts, in spotted snakehead.

Asprosin regulates male reproduction in teleosts: an in vitro study in Channa punctata.

The novel adipokine asprosin, produced by the furin enzymatic cleavage of profibrillin 1 protein (encoded by the Fbn1 gene), is implicated in regulating many physiological functions, including reproduction in mammals. In males, asprosin is reported to increase sperm density, sperm motility, and steroid production by interacting with Olfr734, which belongs to the G-protein-coupled receptor family (GPCR). In 2023, our group predicted and characterized asprosin in silico for the first time and demonstrated the robust expression of fbn1, and furin in the gonads of teleost spotted snakehead (ss) Channa punctata.

Survival Analysis of the Geriatric Population having Multiple Diseases in the Jammu District, J and K, India.

Aging is a complex, multifactorial, and inevitable process, which begins before birth and continues throughout the life. Multimorbidity prevailing among the geriatric population is an important health challenge for most of the developing countries. To examine the effect of gender and increasing age on the survival of the geriatric population suffering from multimorbidity.

From Cirrhosis to the Dysbiosis (A Loop of Cure or Complications?).

Gut dysbiosis and liver cirrhosis are two corelated complications that highly disturbs the metabolism of a normal human body. Liver cirrhosis is scarring of the hepatic tissue and gut dysbiosis is the imbalance in the microbiome of the gut. Gut dysbiosis in cirrhosis occurs due to increased permeability of the intestinal membrane which might induce immune responses and damage the normal functioning of the body.

Exploring the Therapeutic Potential of Traditional Medicinal Foods in Cancer Treatment: Molecular Evidence and Bioactivities.

Traditional medicinal foods derived from natural sources have gained increasing attention in recent years due to their perceived health benefits and potential therapeutic properties and are deeply rooted in cultural practices. This review aimed at understanding their potential health benefits, emphasizes the need to identify the key bioactive substances in traditional home medicine. We have discussed the bioactive properties, molecular targets, and anti-cancer effects of various compounds such as curcumin, genistein, berberine, resveratrol, and, quercetin present in traditional medicinal foods.

Asprosin-mediated regulation of ovarian functions in mice: An age-dependent study.

Asprosin is a recently discovered adipokine reported to be involved in the modulation of mammalian gonadal functions. Preliminary investigations suggest its role in regulation of ovarian functions in rodents as well as bovids. In addition, increased levels of the adipokine during human ovarian pathophysiologies implicate it in disease progression and severity.

Microwave-Assisted Selective Nucleopalladation-Triggered Cascade Process: Synthesis of Highly Functionalized 3-Chloro-1-indenes.

A nucleopalladation-triggered cascade transformation of internal alkynes bearing an amino nucleophile and an electrophilic enone was investigated under unconventional microwave-assisted conditions. Among the three possible pathways, the chloropalladation-triggered domino process proceeded selectively to furnish 3-chloro-1-indenes in good to excellent yields. The reactions under microwave irradiation were completed in 30 min, and the conventional heating required 3-5 h for completion.

A 'click' based fluorescent probe mimicking the IMPLICATION logic gate for Cu(II) and Pb(II) sensing: DFT and molecular docking studies.

'Click' derived 1,2,3-triazole appended scaffolds are intriguing candidates for selective metal ion recognition because of their stereospecificity and efficiency. The presented report uses the 'click' approach to introduce a glyoxal bis-(2-hydroxyanil)-based chemosensor probe (GT) the CuAAC pathway, which can selectively detect Cu(II) and Pb(II) ions, both of which are among the most hazardous and perturbing environmental pollutants. NMR spectroscopy, IR spectroscopy, and mass spectrometry (LCMS) were used to successfully characterize the synthesized probe.

An Energetic and Topological Approach to Understanding the Interplay of Noncovalent Interactions in a Series of Crystalline Spiropyrrolizine Compounds.

Synthesis of quinoline-containing spiropyrrolizine was achieved via a 1,3-dipolar cycloaddition reaction of azomethine ylide (generated in situ from ninhydrin and l-proline) and ()-2-styrylquinoline. The synthesized compounds were characterized by H NMR, C NMR, HRMS, and single-crystal XRD analysis. The XRD data revealed that the solid-state structures of the compounds belong to the monoclinic system of the space group 2/ and are stabilized through various weak noncovalent interactions such as C-H···O, C-H···π, and π···π interactions.

Revealing the Role of Solvent in -Oxypalladation-Triggered Regiocontrolled Domino Reactions for the Synthesis of Benzazepine- and Tetrahydroquinoline-Containing Scaffolds: A Combined Computational and Experimental Study.

Palladium-catalyzed regiocontrolled intramolecular oxypalladation-initiated cascades of multifunctional internal alkyne bearing an -tosyl tether deliver functionalized benzazepine as an exclusive product via 6- pathway in 1,4-dioxane solvent and tetrahydroquinoline scaffold as a major product via the 5- pathway in the DMSO solvent. The role of the solvent in controlling the regioselectivity is still unknown which can be a major hurdle for further reaction development. Moreover, the reaction in DMSO suffered from having a mixture of products, and no exclusive formation of tetrahydroquinoline was achieved.

Quantitative analysis of soil quality around brick kilns using pollution indices and ANOVA in Jammu district of Jammu and Kashmir, India.

The study investigated soil quality around brick kilns in the Jammu district of Jammu and Kashmir, analyzing 200 samples from 50 sites for selected parameters such as pH, electrical conductiv1ity, soil temperature, organic carbon content, organic matter, macronutrients, and heavy metals. The findings revealed that soil electrical conductivity ranged from 0.33 to 0.

Observation of Strong Nuclear Suppression in Exclusive J/ψ Photoproduction in Au+Au Ultraperipheral Collisions at RHIC.

We report a measurement of exclusive J/ψ and ψ(2s) photoproduction in Au+Au ultraperipheral collisions at sqrt[s_{NN}]=200  GeV using the STAR detector. For the first time, (i) the ψ(2s) photoproduction in midrapidity at the Relativistic Heavy-Ion Collider has been experimentally measured; (ii) nuclear suppression factors are measured for both the coherent and incoherent J/ψ production. At average photon-nucleon center-of-mass energy of 25.

Ag/Cu doped polyaniline hybrid nanocomposite-based novel gas sensor for enhanced ammonia gas sensing performance at room temperature.

Hybrid nanocomposites, which comprise organic and inorganic materials, have gained increasing attention in applications for enhanced sensing response to both reducing and oxidation gases. In this study, a novel nanocomposite is synthesized using chemical polymerization by reinforcing Ag/Cu nanoparticles with different concentrations doped into the polyaniline matrix. This hybrid nanocomposite is used as a sensing platform for ammonia detection with different concentrations (ppm).

Therapeutic approaches and novel antifibrotic agents in renal fibrosis: A comprehensive review.

Renal fibrosis (RF) is one of the underlying pathological conditions leading to progressive loss of renal function and end-stage renal disease (ESRD). Over the years, various therapeutic approaches have been explored to combat RF and prevent ESRD. Despite significant advances in understanding the underlying molecular mechanism(s), effective therapeutic interventions for RF are limited.

Quinoa: A Promising Crop for Resolving the Bottleneck of Cultivation in Soils Affected by Multiple Environmental Abiotic Stresses.

Quinoa ( Willd.) has gained worldwide recognition for its nutritional values, adaptability to diverse environments, and genetic diversity. This review explores the current understanding of quinoa tolerance to environmental stress, focusing on drought, salinity, heat, heavy metals, and UV-B radiation.

Observation of Medium-Induced Yield Enhancement and Acoplanarity Broadening of Low-p_{T} Jets from Measurements in pp and Central Pb-Pb Collisions at sqrt[s_{NN}]=5.02 TeV.

The ALICE Collaboration reports the measurement of semi-inclusive distributions of charged-particle jets recoiling from a high transverse momentum (high p_{T}) hadron trigger in proton-proton and central Pb-Pb collisions at sqrt[s_{NN}]=5.02  TeV. A data-driven statistical method is used to mitigate the large uncorrelated background in central Pb-Pb collisions.

Domestication of Information and Communication Technologies into Family Systems: A Conceptual Framework Evaluating Family Health.

As the world undergoes its fourth industrial revolution, digital media are becoming more prevalent in both rural and urban communities. This shift has had a profound impact on our daily lives, transforming the way we live, work, and communicate. Although technology now plays a crucial role in our daily routine, it can lead to interference in human relationships, a phenomenon referred to as technoference.

Cortisol: Biosensing and detection strategies.

Cortisol, a crucial steroid hormone synthesized by the adrenal glands, has diverse impacts on multiple physiological processes, such as metabolism, immune function, and stress management. Disruption in cortisol levels can result in conditions like Cushing's syndrome and Addison's disease. This review provides an in-depth exploration of cortisol, covering its structure, various forms in the body, detection methodologies, and emerging trends in cancer treatment and detection.

A questionnaire study regarding knowledge, attitude and usage of artificial intelligence and machine learning by the orthodontic fraternity of Northern India.

Aim: The aim of the questionnaire study was to determine the knowledge, attitude, and perception of orthodontists regarding the role of artificial intelligence in dentistry in general and orthodontics specifically, and to determine the use of artificial intelligence by the orthodontist.

Methods: This cross-sectional study was done among the orthodontists of Northern India (clinicians, academicians, and postgraduates) through a web-based electronic survey using Google Forms. The study was designed to obtain information about AI and its basic usage in daily life, in dentistry, and in orthodontics from the participants.