Relationship between stress and coronary artery disease: A comprehensive review.

Coronary artery disease (CAD) poses a substantial public health challenge. This review examines the intricate relationship between psychological stress and CAD, drawing from recent research spanning the last 5 to 10 years. The literature review is organized around critical themes.

Effects of letrozole alone or in combination with gonadotropins on ovulation induction and clinical pregnancy in women with polycystic ovarian syndrome: a systematic review and meta-analysis of randomized controlled trials.

Objective: To compare letrozole in combination with gonadotropins versus letrozole monotherapy in ovulation induction and clinical pregnancy among infertile women with polycystic ovarian syndrome (PCOS).

Methods: Several databases were searched for available clinical trials from inception until March 2023. We selected randomized controlled trials (RCTs) that compared sequential letrozole/gonadotropin versus letrozole alone among infertile women who met the Rotterdam criteria for PCOS.

Mechanisms of Melanoma Progression and Treatment Resistance: Role of Cancer Stem-like Cells.

Melanoma is the third most common type of skin cancer, characterized by its heterogeneity and propensity to metastasize to distant organs. Melanoma is a heterogeneous tumor, composed of genetically divergent subpopulations, including a small fraction of melanoma-initiating cancer stem-like cells (CSCs) and many non-cancer stem cells (non-CSCs). CSCs are characterized by their unique surface proteins associated with aberrant signaling pathways with a causal or consequential relationship with tumor progression, drug resistance, and recurrence.

Mississippi church leaders' perceptions of challenges and barriers to the use of consumer wearables among community members.

Background: Wearables have begun to play a transformative role in health management and disease prevention.

Objective: This study examined the use of wearable devices in African American communities in Mississippi, USA, through the lens of church leaders.

Methods: We conducted focus groups with church leaders to record their perceptions about the use of wearables of their community members.

Quantification of Artifacts and Image Distortions in 1.5 Tesla Magnetic Resonance Images of a Commercial Multi-Channel Vaginal Cylinder Brachytherapy Applicator Set.

Background: The BEBIG Portio multi-channel applicator provides better target dose coverage and sparing organs-at-risk compared to a single-channel cylinder. However, artifacts and distortions of Portio in magnetic resonance images (MRI) have not yet been reported.

Objective: We aimed to quantify the artifacts and distortions in its 1.

Identification of promising small-molecule inhibitors targeting STK17B for cancer therapeutics: molecular docking and molecular dynamics investigations.

Cancer is a complex disease characterized by the uncontrolled growth of abnormal cells, leading to the formation of tumours. STK17B, a member of the DAPK family, has been implicated in various cancers and is considered a potential therapeutic target. However, no drug in the market has been approved for the treatment of STK17 B-associated cancer disease.

Mortality Trends in Alzheimer's Disease in Mississippi, 2011-2021.

Unlabelled: Alzheimer's disease is the sixth most common cause of death in the United States (U.S.), with one in three adults 65 years of age and older dying of the disease each year.

A systematic review of the evaluation of endocrine-disrupting chemicals in the Japanese medaka () fish.

Japanese medaka () is an acceptable small laboratory fish model for the evaluation and assessment of endocrine-disrupting chemicals (EDCs) found in the environment. In this research, we used this fish as a potential tool for the identification of EDCs that have a significant impact on human health. We conducted an electronic search in PubMed (http://www.

Eco-Friendly Solvent Engineered CsPbI Br Ink for Large-Area and Scalable High Performance Perovskite Solar Cells.

The performance of large-area perovskite solar cells (PSCs) has been assessed for typical compositions, such as methylammonium lead iodide (MAPbI ), using a blade coater, slot-die coater, solution shearing, ink-jet printing, and thermal evaporation. However, the fabrication of large-area all-inorganic perovskite films is not well developed. This study develops, for the first time, an eco-friendly solvent engineered all-inorganic perovskite ink of dimethyl sulfoxide (DMSO) as a main solvent with the addition of acetonitrile (ACN), 2-methoxyethanol (2-ME), or a mixture of ACN and 2-ME to fabricate large-area CsPbI Br films with slot-die coater at low temperatures (40-50 °C).

MedFusionGAN: multimodal medical image fusion using an unsupervised deep generative adversarial network.

Purpose: This study proposed an end-to-end unsupervised medical fusion generative adversarial network, MedFusionGAN, to fuse computed tomography (CT) and high-resolution isotropic 3D T1-Gd Magnetic resonance imaging (MRI) image sequences to generate an image with CT bone structure and MRI soft tissue contrast to improve target delineation and to reduce the radiotherapy planning time.

Methods: We used a publicly available multicenter medical dataset (GLIS-RT, 230 patients) from the Cancer Imaging Archive. To improve the models generalization, we consider different imaging protocols and patients with various brain tumor types, including metastases.

Aspect Ratio and Quantum Confinement Tunable Giant Two-Photon Absorption from 1D CsPbI Perovskite Nanorods.

Herein, we investigate the influence of aspect ratio and quantum confinement on the single-photon (σ) and two-photon absorption cross-section (σ) for perovskite CsPbI nanorod (NR). Notably, experimentally measured data show extremely high σ for CsPbI NR (10.8 × 10 GM) which is five orders of magnitude higher than organic chromophores, and two order of magnitude higher than CsPbBr nanocrystals.

2D Fluorinated Graphene Oxide (FGO)-Polyethyleneimine (PEI) Based 3D Porous Nanoplatform for Effective Removal of Forever Toxic Chemicals, Pharmaceutical Toxins, and Waterborne Pathogens from Environmental Water Samples.

Although water is essential for life, as per the United Nations, around 2 billion people in this world lack access to safely managed drinking water services at home. Herein we report the development of a two-dimensional (2D) fluorinated graphene oxide (FGO) and polyethylenimine (PEI) based three-dimensional (3D) porous nanoplatform for the effective removal of polyfluoroalkyl substances (PFAS), pharmaceutical toxins, and waterborne pathogens from contaminated water. Experimental data show that the FGO-PEI based nanoplatform has an estimated adsorption capacity () of ∼219 mg g for perfluorononanoic acid (PFNA) and can be used for 99% removal of several short- and long-chain PFAS.

MRI motion artifact reduction using a conditional diffusion probabilistic model (MAR-CDPM).

Background: High-resolution magnetic resonance imaging (MRI) with excellent soft-tissue contrast is a valuable tool utilized for diagnosis and prognosis. However, MRI sequences with long acquisition time are susceptible to motion artifacts, which can adversely affect the accuracy of post-processing algorithms.

Purpose: This study proposes a novel retrospective motion correction method named "motion artifact reduction using conditional diffusion probabilistic model" (MAR-CDPM).

Mechanisms of Cell Fusion in Cancer.

Cell-cell fusion is a normal physiological mechanism that requires a well-orchestrated regulation of intracellular and extracellular factors. Dysregulation of this process could lead to diseases such as osteoporosis, malformation of muscles, difficulties in pregnancy, and cancer. Extensive literature demonstrates that fusion occurs between cancer cells and other cell types to potentially promote cancer progression and metastasis.

Discovery of an orally active nitrothiophene-based antitrypanosomal agent.

Human African Trypanosomiasis (HAT), caused by Trypanosoma brucei gambiense and rhodesiense, is a parasitic disease endemic to sub-Saharan Africa. Untreated cases of HAT can be severely debilitating and fatal. Although the number of reported cases has decreased progressively over the last decade, the number of effective and easily administered medications is very limited.

Convergent Adaptation of True Crabs (Decapoda: Brachyura) to a Gradient of Terrestrial Environments.

For much of terrestrial biodiversity, the evolutionary pathways of adaptation from marine ancestors are poorly understood and have usually been viewed as a binary trait. True crabs, the decapod crustacean infraorder Brachyura, comprise over 7600 species representing a striking diversity of morphology and ecology, including repeated adaptation to non-marine habitats. Here, we reconstruct the evolutionary history of Brachyura using new and published sequences of 10 genes for 344 tips spanning 88 of 109 brachyuran families.

Examining motivation factors for African American students' use of consumer wearables.

Purpose: This study was initiated to examine factors that motivate African American students who use wearable devices at an HBCU in Mississippi.

Method: We conducted a correlational research study on undergraduate and graduate students from a southern USA university. The stratified random sample comprised a total of 239 students.

Lacustrine sedimentation by powerful storm waves in Gale crater and its implications for a warming episode on Mars.

This investigation documents that the Rugged Terrain Unit, the Stimson formation, and the Greenheugh sandstone were deposited in a 1200 m-deep lake that formed after the emergence of Mt. Sharp in Gale crater, Mars, nearly 4 billion years ago. In fact, the Curiosity rover traversed on a surface that once was the bottom of this lake and systematically examined the strata that were deposited in its deepest waters on the crater floor to layers that formed along its shoreline on Mt.

The System of Self-Consistent Models: The Case of Henry's Law Constants.

Data on Henry's law constants make it possible to systematize geochemical conditions affecting atmosphere status and consequently triggering climate changes. The constants of Henry's law are desired for assessing the processes related to atmospheric contaminations caused by pollutants. The most important are those that are capable of long-term movements over long distances.

Effects of Probiotics in Adults with Gastroenteritis: A Systematic Review and Meta-Analysis of Clinical Trials.

Probiotics have been widely used in gastroenteritis due to acute and chronic illnesses. However, evidence supporting the effectiveness of probiotics in different health conditions is inconclusive and conflicting. The aim of this study was to review the existing literature on the effects of probiotics on gastroenteritis among adults.