Systemic lupus erythematosus (SLE) is an autoimmune disorder causing a range of symptoms, including pancytopenia, due to antibodies affecting various bodily components.
An African American woman in her 20s with a history of SLE experienced bruising and was undergoing treatment when follow-up tests revealed pancytopenia, leading to further investigation.
Despite suspicion of SLE flare-up or mycophenolate toxicity, a bone marrow biopsy revealed an unusual diagnosis of acute promyelocytic leukemia, highlighting the challenges in diagnosing conditions that overlap with SLE symptoms.