1,551 results match your criteria: "JR Hospital[Affiliation]"

Background: Light-chain cardiac amyloidosis (AL-CA) is associated with structural and functional changes in the left atrium and left ventricle. This study aims to assess the value of the left atrioventricular coupling index (LACI) assessed by three-dimensional echocardiography (3DE) for predicting primary outcome in AL-CA.

Methods: Participants with biopsy-confirmed AL-CA from April 2022 to February 2024 were prospectively analysed.

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Synchronous primary aneurysmal bone cysts: A rare case report and literature review.

Radiol Case Rep

March 2025

Department of Radiology, John H. Stroger, Jr. Hospital of Cook County, 1969 West Ogden Avenue, Chicago, Illinois 60612, USA.

Aneurysmal bone cysts (ABCs) are rare benign osteolytic tumors which occur most frequently within the first two decades of life and can lead to pathological fractures. They have characteristic imaging and histologic features and have historically been classified into two types: primary ABCs, which are true neoplasms linked to specific oncogenes, and secondary ABCs, which are preceded by other bone lesions. The occurrence of multiple concurrent primary ABCs is exceedingly rare; with only a few cases reported in the published literature.

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Importance: Postoperative urinary retention (POUR) is common after reconstructive pelvic surgery. Little is known about the relationship between older age (≥70 years) and POUR after pelvic organ prolapse surgery.

Objectives: We aimed to investigate the relationship between age ≥70 years and POUR.

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Operating on the Oldest-Old: Vaginal Prolapse Surgery Outcomes in Women Over 90.

Urogynecology (Phila)

January 2025

Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, University of Pittsburgh Medical Center, Pittsburgh, PA.

Importance: Women aged 90 years and older ("oldest-old") represent a small but growing population who may experience bothersome pelvic organ prolapse and opt for surgical repair.

Objective: This study aimed to compare perioperative adverse events (AEs) within 8 weeks of prolapse surgery between women ≥90 years and younger patients.

Study Design: We performed a secondary analysis of a dual-center retrospective cohort study of women ≥61 years old undergoing major prolapse surgery from January 2016 to May 2023.

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Impact of Kidney Disease in Patients Undergoing Catheter Directed Interventions for Intermediate to High-Risk Pulmonary Embolism.

Am J Med Sci

January 2025

Department of Medicine, Louisiana State University Health Science Center, Shreveport, LA, USA; Department of Cardiovascular sciences, Louisiana State University Health Science Center at Shreveport, Shreveport, LA, USA.

Background: Catheter-directed interventions (CDIs) for pulmonary embolism (PE) continue to evolve. However, due to the paucity of data, their use has been limited in patients with underlying kidney disease.

Methods: The National Readmission Database (2016-2020) was utilized to identify intermediate to high-risk PE (IHR-PE) patients requiring CDI (thrombectomy, thrombolysis, and ultrasound-assisted thrombolysis).

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Objective: To evaluate mechanical failure rates of retrograde femoral nails in the treatment of distal femur fractures.

Methods: Design: Retrospective chart review.

Setting: Urban Academic Level 1 Trauma Center.

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Background: Percutaneous mechanical aspiration thrombectomy is increasingly being employed as a less invasive alternative for managing right heart masses, including clot in transit.

Aims: We aimed to analyze trends in the use of catheter-directed aspiration (CDA) for right heart masses. Additionally, we analyzed in-hospital outcomes of percutaneous versus surgical approaches for patients with CIT and PE.

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Objective: Primary liver cancer (PLC) is projected to be the third leading cause of cancer mortality in the United States in 2040. We examine the burden of PLC in the United States, stratified by sex, state and aetiological risk factors.

Methods: Data on PLC prevalence, incidence, death and disability-adjusted life years (DALYs) were extracted from the Global Burden of Disease Study 2021.

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Background: Despite extensive research on COVID-19 and its association with myocarditis, limited data are available on readmission rates for this subset of patients. Thirty-day hospital readmission rate is an established quality metric that is associated with increased mortality and cost.

Methods: This retrospective analysis utilized the Nationwide Readmission Database for the year 2020 to evaluate 30-day hospital readmission rates, risk factors, and clinical outcomes among COVID-19 patients who presented with myocarditis at their index hospitalization.

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Background: Limited data is available regarding in-hospital outcomes of patients undergoing high-risk percutaneous coronary intervention (HR-PCI) with Impella with and without a prior history of coronary artery bypass grafting (CABG).

Methods: We performed a retrospective study from the Nationwide Inpatient Sample from year 2016 to 2020. We identified patients who underwent Impella and percutaneous coronary intervention on the same day and excluded those with cardiogenic shock.

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Parathyroid gland (PG) auto-transplantation is performed to preserve the function of de-vascularized or unintentionally removed PGs, however, little has been published about the technique and outcomes in children. In our study, we aimed to present the results of PG auto-transplantation in children undergoing thyroidectomy or parathyroidectomy at a tertiary single institution. A retrospective review identified 14 patients (<18 years of age) who underwent PG auto-transplantation from January 2000 to December 2022.

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Background/objectives: Dry eye disease (DED) is an exceedingly common diagnosis in patients, yet recent analyses have demonstrated patient education materials (PEMs) on DED to be of low quality and readability. Our study evaluated the utility and performance of three large language models (LLMs) in enhancing and generating new patient education materials (PEMs) on dry eye disease (DED).

Subjects/methods: We evaluated PEMs generated by ChatGPT-3.

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Introduction: Transcatheter mitral valve-in-valve replacement (TMVR ViV) is becoming a favorable, less invasive procedure among high-risk patients to manage mitral valve dysfunction. We aimed to investigate the trends of the predictors and outcomes of the procedure.

Methods: The national inpatient sample databases of 2016-2020 were analyzed using STATA 17 software and ICD-10 codes for TMVR ViV, with stratification for mitral stenosis (MS) or Mitral regurgitation (MR) as etiology for prosthetic valve dysfunction.

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Background: Stimulant use has been associated with an increased risk of stroke, though data on clinical characteristics and exact risk are limited. This retrospective case-control study examines stroke risk in individuals with stimulant use disorder using data from a national U.S.

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Article Synopsis
  • - Gastroesophageal reflux disease (GERD) affects about 20% of adults in the U.S., and while proton pump inhibitors (PPIs) are commonly used to treat it, they can have long-term side effects; endoscopic full-thickness plication (EFTP) is a minimally invasive alternative being explored.
  • - A meta-analysis included three randomized controlled trials (RCTs) with 272 patients, showing that EFTP significantly reduced PPI usage and improved quality of life scores related to GERD after three months, although no significant differences were found in some specific measures like DeMeester scores.
  • - The study concludes that EFTP shows promise as an effective treatment for GERD, leading to lower PPI
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Introduction: This study investigates seasonal variations in eosinophilic esophagitis (EoE)-related emergency department visits among adults.

Methods: We analyzed the National Emergency Department Sample (2016-2021), identifying adult patients with EoE using ICD-10 codes. Generalized additive models assessed seasonal patterns.

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Background: Hepatitis B virus (HBV) infection causes liver disease, including hepatocellular carcinoma. Controlling viral activity is crucial to reducing complications. Tenofovir may offer benefits over entecavir, but it is unclear if switching from entecavir to tenofovir improves outcomes.

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Article Synopsis
  • - Invasive mucinous adenocarcinoma (IMA) of the lung has unique features such as multicentric lesions and low distant metastasis but a poor prognosis, with median survival under a year.
  • - While treatment options are limited, lung transplantation in selected IMA patients has shown improved survival, but with high rates of recurrence often linked to the primary tumor.
  • - A notable case of bilateral lung transplantation using cardiopulmonary bypass for stage ⅣA lung-limited IMA achieved 15 months of stable health without disease recurrence or organ rejection, and IMA's characteristics and outcomes are discussed in relation to prior classifications and other lung transplantation cases.
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Article Synopsis
  • The study evaluated how frailty affects outcomes after endoscopic retrograde cholangiopancreatography (ERCP) in the U.S., using data from the National Readmission Database between 2016 and 2020.
  • Among 885,416 ERCP index admissions, 9.9% experienced readmissions within 30 days, with higher readmission rates and odds for those categorized as intermediate and high frailty compared to low frailty.
  • Increased frailty also correlated with longer hospital stays and higher hospitalization costs, as well as a greater risk of inpatient mortality for those in the intermediate and high frailty groups.
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Article Synopsis
  • The study investigates the outcomes of different Mechanical Circulatory Support (MCS) devices, specifically comparing ECMO and Impella, in patients with cardiogenic shock due to acute myocardial infarction (AMI-CS).
  • Data from the national readmission database revealed that the majority of patients received Impella, while the ECMO group was generally younger with fewer health issues.
  • Despite advances in MCS technologies, there was no significant change in mortality rates for AMI-CS between 2016 and 2020, and ECMO had higher adverse outcomes compared to Impella, indicating a need for further research.
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Article Synopsis
  • The World Health Organization emphasizes the importance of Mother's Own Milk (MOM) and donor human milk (DHM) for breastfeeding support, especially in developing countries like Nigeria, where DHM is often scarce.
  • A study in Ekiti State found that out of 321 healthcare workers surveyed, while many had good knowledge of DHM, there were varying attitudes towards its safety and efficacy, with some reluctance to accept DHM for their own children.
  • Overall, the study showed that most healthcare workers would encourage mothers to donate milk and use DHM for infants in their care, but negative perceptions and influences from the media impacted their openness to DHM.
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Sex disparities in outcomes of transcatheter aortic valve implantation- a multi-year propensity-matched nationwide study.

Int J Cardiol

January 2025

Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA; Division of Cardiology, Department of Medicine, Yale New Haven Health, Bridgeport Hospital, Bridgeport, CT, USA.

Article Synopsis
  • This study looked at how men and women do after a heart procedure called TAVI, which helps with a problem called aortic stenosis.
  • It found that women faced more serious complications right after the procedure, like higher chances of dying and having strokes, compared to men.
  • However, men had a higher chance of needing to go back to the hospital within 30 and 90 days after the procedure, but both men and women got better faster from 2016 to 2020.
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Objective: To evaluate postoperative outcomes among patients undergoing colon surgery who receive perioperative prophylaxis with ertapenem compared to other antibiotic regimens.

Design And Setting: Multicenter retrospective cohort study among adults undergoing colon surgery in seven hospitals across three health systems from 1/1/2010 to 9/1/2015.

Methods: Generalized linear mixed logistic regression models were applied to assess differential odds of select outcomes among patients who received perioperative prophylaxis with ertapenem compared to other regimens.

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Article Synopsis
  • A phase I/II trial evaluated the safety and effectiveness of toripalimab alongside chemoradiotherapy for patients with locally advanced cervical squamous cell carcinoma.
  • Twenty-two patients participated, receiving a combination of toripalimab and concurrent chemoradiotherapy, with a focus on safety and progression-free survival over two years.
  • Results indicated a high objective response rate of 100%, with two-year progression-free survival at 81.8% and overall survival at 90.9%, demonstrating promising outcomes for this treatment combination.
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