622 results match your criteria: "JED); the Robert Graham Center[Affiliation]"

Identification of Candidate Characteristics that Predicted a Successful Anesthesiology Residency Program Match in 2024: An Anonymous, Prospective Survey.

J Educ Perioper Med

January 2025

Tricia Pendergrast is a Resident Physician in the Department of Anesthesiology at University of Michigan, Ann Arbor, MI. Jed Wolpaw is the Core Residency Program Director in the Department of Anesthesiology and Critical Care Medicine at Johns Hopkins University School of Medicine, Baltimore, MD. Michael P. Hofkamp is the Director of Undergraduate Medical Education in the Department of Anesthesiology at Baylor Scott & White Medical Center-Temple, Temple, TX.

Background: The primary aim of our study was to identify candidate characteristics that predicted a successful outcome for applicants to anesthesiology residency programs in the 2024 Main Residency Match. The secondary aim of our study was to assess the impact of gold and silver signals on the application process.

Methods: The Baylor Scott & White Research Institute institutional review board approved this study.

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Jacquet's erosive dermatitis (JED) is a severe irritant dermatitis characterized by erosive genital and perianal lesions, often misdiagnosed due to overlapping clinical features. This case report presents two adult cases of JED with distinct clinical and dermoscopic findings. Dermoscopy revealed a characteristic polymorphic vascular pattern, including short linear, curved, coiled, dotted, and globular vessels, aiding in the diagnosis and differentiation from similar conditions.

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The stigma of mental illness, among a larger set of barriers to help seeking, has been understudied among teens. These barriers and the sources of support were examined through an online survey with 1,428 U.S.

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Article Synopsis
  • Gallstone disease significantly strains healthcare resources, particularly through emergency cholecystectomy, yet there's limited research on the risk factors that lead to such emergencies in patients scheduled for elective surgery.
  • A study conducted in Jeddah, Saudi Arabia, analyzed 823 patients, revealing that 15.67% underwent emergency cholecystectomy, often due to longer waiting times and previous emergency department visits.
  • Key findings indicated that patients with acute cholecystitis or pancreatitis, and those with multiple prior ED visits, are at a much higher risk of requiring emergency surgery.
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Bacterial peptidoglycan as a living polymer.

Curr Opin Chem Biol

December 2024

Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, 46556, USA. Electronic address:

The peptidoglycan manifests as a multifaceted component of the bacterial cell wall. Throughout the lifecycle of the bacterium, the peptidoglycan is deconstructed, rebuilt, and remodeled for bacterial cell growth and replication. Degradation products of the peptidoglycan serve as precursors for cell-wall building blocks via recycling processes and as signaling molecules.

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Background/objectives: Telenutrition has been reported to enable dietitians to support outpatients remotely in an accessible and convenient state. The literature shows that both telemonitoring and health coaching are effective approaches for achieving a greater impact on weight loss and the client's compliance with their diet. The purpose of the present study was to assess the impact of a telenutrition weight loss program on weight reduction, supported with telemonitoring and health coaching.

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Background: Low back pain (LBP) is one of the most common conditions in the United States. Dysfunctional patterns of the erector spinae (ES) and gluteus medius (GM) muscles often accompany episodes of LBP.

Objectives: To evaluate the intra-rater reliability of rehabilitative ultrasound imaging (RUSI) in obtaining thickness measurements of the ES and GM muscles at rest and during submaximal contraction.

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Transplantation of ex vivo engineered hematopoietic stem cells (HSCs) can lead to robust clinical responses but carries risks of adverse events from bone marrow mobilization, chemotherapy conditioning and other factors. HSCs have been modified in vivo using lipid nanoparticles (LNPs) decorated with targeting moieties, which increases manufacturing complexity. Here we screen 105 LNPs without targeting ligands for effective homing to the bone marrow in mouse.

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Article Synopsis
  • The text refers to a correction made to a scholarly article identified by the DOI 10.3389/fonc.2024.1323176.
  • The correction likely addresses inaccuracies or errors in the original publication.
  • Such corrections are important for maintaining the integrity of academic research and ensuring that readers have access to accurate information.
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Article Synopsis
  • X-linked hypophosphatemia (XLH) is a genetic disorder that leads to significant skeletal issues and impacts physical function and work productivity in adults.
  • A study analyzed data from 281 XLH patients, revealing that many are not employed or rely on disability payments; those with fewer orthopedic surgeries and better physical function are more likely to have full-time jobs.
  • Overall, the findings indicate that XLH severely affects work productivity, with younger patients, worse pain, and higher orthopedic surgery counts linked to more demanding job roles.
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How Psychedelics Modulate Multiple Memory Mechanisms in Posttraumatic Stress Disorder.

Drugs

November 2024

Department of Psychiatry and Behavioral Sciences, Center for Psychedelic Research and Therapy, The University of Texas at Austin Dell Medical School, 1601 Trinity Street, Bldg. B, Stop Z0600, Austin, TX, 78712, USA.

Posttraumatic stress disorder (PTSD) is a psychiatric disorder with defining abnormalities in memory, and psychedelics may be promising candidates for the treatment of PTSD given their effects on multiple memory systems. Most PTSD and psychedelic research has investigated memory with fear conditioning and extinction. While fruitful, conditioning and extinction provide a limited model of the complexity of PTSD and phenomenology of psychedelics, thereby limiting the refinement of therapies.

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Development and evaluation of a spaced eLearning intervention for nurses in enhancing urinary catheter management - A co-design study in partnership with research end-users.

Nurse Educ Today

January 2025

School of Nursing, Faculty of Science, Medicine & Health, University of Wollongong, Australia, Australian Centre for Integration of Oral Health (ACIOH), Ingham Institute for Applied Medical Research, Building 41: Room 118, University of Wollongong, NSW, 2522, Australia. Electronic address:

Background: Nurses play a critical role in supporting patients in self-managing their indwelling urinary catheters and preventing avoidable hospital presentations. This study aimed to explore the effectiveness of a co-designed educational approach developed to enhance nurses' ability to provide optimal care for patients with catheters.

Aim: The primary aim of this study was to enhance nurses' knowledge and skills in urinary catheterisation, care, and management.

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Article Synopsis
  • Encephalitis, meningitis, and meningoencephalitis pose major clinical challenges due to their varied causes and serious complications, necessitating a high suspicion index for effective treatment.
  • The study conducted at King Abdulaziz Medical City in Jeddah analyzed data from 233 patients, revealing that meningitis was the most common diagnosis, primarily caused by bacterial agents, particularly impacting younger children and older adults with higher mortality rates.
  • The findings highlight the need for accurate diagnosis and tailored treatment plans to improve patient outcomes, suggesting further research is necessary to refine healthcare strategies for these neurological infections.
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Purpose: Pre-operative fourth ventricle roof angle (FVRA) has recently been highlighted as a novel radiographic predictor of clinical severity in Chiari type-I malformation (CM-I) as reported by Seaman et al. (J Neurosurg Pediatr 25:1-8, 2021). This has led to suggestions that FVRA could be included in algorithms to determine indications for surgery.

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Coronary atherosclerotic plaque characterization with silicon-based photon-counting computed tomography (CT): A simulation-based feasibility study.

Med Phys

December 2024

Biomedical Imaging Center, Center for Biotechnology and Interdisciplinary Research, Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, New York, USA.

Background: Recent photon-counting computed tomography (PCCT) development brings great opportunities for plaque characterization with much-improved spatial resolution and spectral imaging capability. While existing coronary plaque PCCT imaging results are based on CZT- or CdTe-materials detectors, deep-silicon photon-counting detectors offer unique performance characteristics and promise distinct imaging capabilities.

Purpose: This study aims to numerically investigate the feasibility of characterizing plaques with a deep-silicon PCCT scanner and to demonstrate its potential performance advantages over traditional CT scanners using energy-integrating detectors (EID).

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Pomalidomide for Epistaxis in Hereditary Hemorrhagic Telangiectasia.

N Engl J Med

September 2024

From Massachusetts General Hospital, Boston (H.A.-S.); University of North Carolina, Chapel Hill (R.S.K.), and RTI International, Research Triangle Park (D.M., L.B., B.A.C., S.M.T.) - both in North Carolina; Mayo Clinic, Rochester, MN (V.N.I.); University of Pennsylvania, Philadelphia (A.M.P.); Medical College of Wisconsin, Milwaukee (J.E.D.); Johns Hopkins University, Baltimore (C.R.W.), and CureHHT, Monkton (M.C.) - both in Maryland; University of Utah, Salt Lake City (K.J.W.); University of California, San Francisco, San Francisco (M.B.C.); University of Florida, Gainesville (M.S.Z.); University of California, San Diego, La Jolla (J.Y.Z.); and Taussig Cancer Center and Lerner Research Institute (K.R.M.), Cleveland Clinic (J.P., L.W., K.R.M.), Cleveland.

Article Synopsis
  • Hereditary hemorrhagic telangiectasia (HHT) is a genetic disorder that leads to severe nosebleeds and related health issues, primarily affecting patients' quality of life due to iron-deficiency anemia from frequent epistaxis.
  • A study was conducted where 144 participants were given either pomalidomide or a placebo for 24 weeks to assess the drug's effectiveness in reducing nosebleed severity and improving quality of life, with results favoring the pomalidomide group.
  • The results showed that those taking pomalidomide experienced a greater decrease in bleeding scores and improved quality-of-life measures, although there were some additional side effects observed in the pomalidomide group.
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Introduction: Venous thromboembolism, which includes deep-vein thrombosis and pulmonary embolism, is the third most common cardiovascular disease after myocardial infarction and stroke. This study aimed to determine the effect of Doppler ultrasound on the prophylaxis and prevention of postoperative venous thromboembolism in gynecological oncology.

Method: This is a retrospective cohort study of procedures performed at King Abdulaziz Medical City in Jeddah, Saudi Arabia, between 2016 and 2021.

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Development and psychometric evaluation of the catheter assessment, management and performance (CAMP) scale for nurses.

Nurse Educ Pract

October 2024

School of Nursing, Faculty of Science, Medicine & Health, University of Wollongong, Australia; Australian Centre for Integration of Oral Health (ACIOH), Ingham Institute for Applied Medical Research, Locked Bag 7103, Liverpool NSW 2170, Australia. Electronic address:

Aim: To develop and test the psychometric properties of a self-administered scale to assess the knowledge, skills, attitudes and behaviour of nurses to support the self-management of patients living with indwelling urinary catheters.

Background: Nurses are pivotal in supporting patients with urinary catheter self-management to prevent potentially avoidable hospital presentations. However, no validated scale is available to assess nurses' attitudes and readiness for this task.

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Article Synopsis
  • - Neurofibromatosis type 1 (NF1) is a genetic disorder that requires long-term monitoring due to its complex symptoms, which can greatly impact patients' quality of life and create economic challenges for families.
  • - The introduction of MEK inhibitors like selumetinib has improved treatment options for NF1-related plexiform neurofibromas, but effective care depends on early detection of the disorder.
  • - Experts in the Arabian Gulf region recommend better diagnosis, management strategies, and the establishment of NF1 centers to enhance patient care and outcomes, along with affordable genetic testing.
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Background: Existing data suggested a rural-urban disparity in thrombolytic utilization for ischemic stroke. Here, we examined the use of guideline-recommended stroke care and outcomes in rural hospitals to identify targets for improvement.

Methods: This retrospective cohort study included patients (aged ≥18 years) treated for acute ischemic stroke at Get With The Guidelines-Stroke hospitals from 2017 to 2019.

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Catalytic New Resources For Health Workers.

Health Aff (Millwood)

September 2024

Jed Meline is director of policy and advocacy at Project HOPE.

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Introduction: COVID-19 is a viral infection affecting the respiratory system, primarily. It has spread globally ever since it first appeared in China in 2019. The use of high-flow nasal oxygen (HFNO) for the treatment of COVID-19 has not been well established.

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Introduction: Transcatheter aortic valve implantation (TAVI) has dramatically changed the approach to treating aortic stenosis, particularly for patients unsuitable for surgical aortic valve replacement. Nevertheless, the possibility of quick deterioration of kidney function, known as acute kidney injury (AKI), post operation is considered one of the complications.

Objectives: The study aimed to determine the incidence of AKI in adults post TAVI.

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