1 results match your criteria: "J.M.D.) and Western General Hospital (W.J.L.J.) - both in Edinburgh.[Affiliation]"
Breast-Conserving Surgery with or without Irradiation in Early Breast Cancer.
N Engl J Med
February 2023
From the University of Edinburgh (I.H.K., L.J.W., D.A.C., J.M.D.) and Western General Hospital (W.J.L.J.) - both in Edinburgh.
Article Synopsis
- A phase 3 randomized trial was conducted to explore the effects of omitting radiotherapy in older women (65+) with hormone receptor-positive early breast cancer after breast-conserving surgery.
- Of the 1326 participating women, those who did not receive radiotherapy had a significantly higher local breast cancer recurrence rate (9.5%) compared to those who did (0.9%), but overall survival rates were nearly the same in both groups (around 80.8%).
- The findings suggest that while omitting radiotherapy may lead to higher local recurrences, it does not impact distant recurrence or overall survival for these patients on adjuvant endocrine therapy.