329 results match your criteria: "J.J. Strossmayer University of Osijek[Affiliation]"

In this work, a novel fluorescent probe (compound 2) based on the Intramolecular charge transfer (ICT) mechanism was designed and successfully applied to determine HS in human serum. Fluorophore 1,8-naphthalimide was chosen, while the azide group was the recognition group for HS determination. By introducing p-toluidine moiety on the imide part of the molecule, a donor-acceptor (D-A) conjugated system was formed.

View Article and Find Full Text PDF

Calcifediol and paricalcitol as adjunctive therapies for HSV-1 keratitis and corneal perforation: A case report.

Medicine (Baltimore)

December 2024

Laboratory of Neurobiology, Department of Medical Biology and Genetics, Faculty of Medicine Osijek, J. J. Strossmayer University of Osijek, Osijek, Croatia.

Rationale: Herpes simplex virus 1 establishes a latent infection in trigeminal ganglia. Reactivation causes cold sores, as well as viral keratitis. The purpose of this study was to report potential benefits of using active vitamin D receptor ligands (VDR-agonists) as adjunctive therapies for the treatment of infectious corneal perforations, and prevention of HSV recurrence.

View Article and Find Full Text PDF

Background/objectives: Despite the increased use of new resorbable magnesium membranes, there are no reported cases or studies on the use of resorbable magnesium membranes in combination with bone grafts for alveolar ridge preservation (ARP) in cases with severe buccal bone wall dehiscence. This case report aimed to evaluate the effectiveness of the magnesium membrane shield technique in conjunction with bone grafting for ARP, assessing both clinical outcomes and histological bone regeneration.

Methods: A 44-year-old female patient presented with a vertical fracture on tooth 24 (FDI Notation System) accompanied with complete destruction of the buccal bone wall.

View Article and Find Full Text PDF

The Role of Active Brown Adipose Tissue in Patients With Pheochromocytoma or Paraganglioma.

Endocr Pract

November 2024

Department of Endocrinology ASO/EASO COM, King's College Hospital NHS Foundation Trust, London, United Kingdom; Faculty of Life Sciences and Medicine, School of Cardiovascular and Metabolic Medicine and Sciences, Obesity, Type 2 Diabetes and Immunometabolism Research Group, King's College London, London, United Kingdom. Electronic address:

Objectives: Metabolically-active brown adipose tissue (aBAT) is a common finding on fluorodeoxyglucose positron emission tomography (FDG-PET) imaging in patients with pheochromocytoma or paraganglioma (PPGL). In addition to its clinical significance, we aimed to explore the prevalence of this finding on FDG-PET imaging in patients with PPGL.

Methods: We conducted a systematic review and meta-analysis of prospective and retrospective studies.

View Article and Find Full Text PDF

The aim of the study is to explore the role of child's executive functions in the relation between child's externalizing and internalizing problems and caregiver strain in early school age children. The caregiver strain refers to providing nurture and care for a dependent family member. A sample includes 175 caregiver-child dyads and 36 school teachers.

View Article and Find Full Text PDF

Introduction: The aim of this study was to investigate serum levels of galectin-3 (Gal-3) and N-terminal pro-brain Natriuretic Peptide (NT-proBNP) in patients with stable obstructive coronary artery disease, as well as their potential to predict clinical outcomes.

Methods: This was a single-center cross-sectional cohort study. 168 patients were divided into three groups: percutaneous coronary intervention (PCI) group (N 64), coronary artery bypass graft surgery (CABG) group (N 57), and group with no coronary stenosis (N 47).

View Article and Find Full Text PDF

Implications of Dysnatremia and Endocrine Disturbances in COVID-19 Patients.

Int J Mol Sci

September 2024

Clinical Institute of Nuclear Medicine and Radiation Protection, University Hospital Centre Osijek, 4 Josip Huttler Street, HR-31000 Osijek, Croatia.

Article Synopsis
  • - Sodium imbalance is a frequent issue in COVID-19, often caused by hormonal disruptions, particularly involving conditions like hypothyroidism and hypocortisolism, which can both lead to lower sodium levels (hyponatremia).
  • - Hypocortisolism, resulting from adrenal or pituitary issues, affects the kidneys' ability to excrete water properly and increases the secretion of antidiuretic hormone (ADH), further diluting sodium levels.
  • - The review emphasizes that the relationship between COVID-19 and sodium imbalance is complicated by factors like the renin-angiotensin-aldosterone system (RAAS) being impacted by the virus, highlighting the need for more research to better manage these disturbances in affected
View Article and Find Full Text PDF

The aim of this study was to evaluate the efficacy of autologous dentin (AD), bovine xenograft (BX) and magnesium-enriched bovine xenograft (BX + Mg) in the healing of critical cranial bone defects (CCBDs) in rats. Eighty male Wistar rats were divided into four groups: BX, BX + Mg, AD and the control group (no intervention). Eight mm CCBDs were created and treated with the respective biomaterials.

View Article and Find Full Text PDF

Genomic diversity and population structure of Carniolan honey bee in its native habitat.

BMC Genomics

September 2024

Faculty of Agrobiotechnical Sciences Osijek, J.J. Strossmayer University of Osijek, Vladimira Preloga 1, Osijek, 31000, Croatia.

Article Synopsis
  • Recent research highlights the importance of understanding genetic diversity in honey bee populations due to declines caused by human activities and climate change, focusing specifically on Carniolan honey bees in Central and South-Eastern Europe.
  • The study used advanced genetic analysis methods to distinguish Carniolan honey bees from Italian honey bees and discovered varying levels of genetic mixing and relationships among different populations based on geographic location.
  • Findings suggest that while Carniolan honey bees exhibit genetic homogeneity overall, they possess sufficient genetic diversity within their native range that requires monitoring to support future breeding programs.
View Article and Find Full Text PDF

Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), is becoming more prominent globally due to an increase in the prevalence of obesity, dyslipidemia, and type 2 diabetes. A great deal of studies have proposed potential treatments for MASLD, with few of them demonstrating promising results. The aim of this study was to investigate the potential effects of (-)-epicatechin (EPI) on the development of MASLD in an in vitro model using the HepG2 cell line by determining the metabolic viability of the cells and the levels of PPARα, PPARγ, and GSH.

View Article and Find Full Text PDF

Understanding Adult Central Nervous System Hemangioblastomas: A Systematic Review.

World Neurosurg

November 2024

Semmes Murphey Neurologic & Spine Institute, Memphis, Tennessee, USA; Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA. Electronic address:

Background: Adult hemangioblastomas (HBs) are rare World Health Organization central nervous system (CNS) grade 1 tumors, particularly affecting the posterior cranial fossa. They exhibit a gender bias, impacting men in their fifth and sixth decades of life and manifesting sporadically or as part of von Hippel Lindau disease. Understanding the intricacies of CNS HBs is crucial for clinical decision-making.

View Article and Find Full Text PDF

Introduction: Thirty-three-year-old female underwent diagnostic work-up for chronic headaches.

Case Report: Cerebral DSA on the right side showed fetal posterior cerebral artery (PCA) with unusually shaped arterial malformation on its proximal part. Malformation was formed by multiple convolutions and loops with no arteriovenous shunting.

View Article and Find Full Text PDF

Advanced chemically modified electrodes and platforms in food analysis and monitoring.

Food Chem

December 2024

Institute of Analytical Chemistry, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Radlinskeho 9, 812 37 Bratislava, Slovakia. Electronic address:

Electrochemical sensors and electroanalytical techniques become emerging as effective and low-cost tools for rapid assessment of special parameters of the food quality. Chemically modified electrodes are developed to change properties and behaviour, particularly sensitivity and selectivity, of conventional electroanalytical sensors. Within this comprehensive review, novel trends in chemical modifiers material structure, electrodes construction and flow analysis platforms are described and evaluated.

View Article and Find Full Text PDF

The use of the comet assay in large biomonitoring studies may present logistical and technical challenges because of the processing of numerous samples. Proper sample preservation becomes imperative to prevent spurious DNA breakage. Previous research has shown the feasibility of conducting the comet assay on frozen blood samples, highlighting the potential of freezing at - 80 °C in preserving DNA integrity.

View Article and Find Full Text PDF

This study investigated the releasing dynamics of serum ST2 and calprotectin in patients with acute IS. The study included acute IS patients (N = 20) with an NIH Stroke Scale score ≥8. Sampling was performed at seven time points: after admission (T0) and at the following 24 h consecutive intervals (T1-T6).

View Article and Find Full Text PDF

Background: The coccoid form of ( is resistant to antibiotics. There are only a few studies that have analyzed the frequency of coccoid in patients with gastritis. The aim of this work was to examine the correlation between the form and the pathohistological characteristics of the stomach in patients with gastritis.

View Article and Find Full Text PDF

Heart failure (HF) with mid-range or mildly reduced ejection fraction (HFmrEF) is a separate clinical entity in the HF spectrum, with a left ventricular ejection fraction ranging from 40 to 49%. While sodium glucose co-transporter 2 inhibitors have become the cornerstone therapy for the entire HF spectrum, there are a few clinical trials of HFmrEF. This prospective observational study was conducted at Dubrava University Hospital, Zagreb, Croatia, from May 2021 to October 2023.

View Article and Find Full Text PDF

Background: Patients with rheumatoid arthritis have significant cardiovascular mortality and morbidity.

Objective: To investigate the effects of chronic inflammation in rheumatoid arthritis on cardiovascular morbidity association with cardiovascular risk factors risk factors. Mortality report is secondary just to show trends without sufficient statistical power as it is accidental endpoint.

View Article and Find Full Text PDF

Purpose: This study investigated the effect of consumption of table eggs enriched with n-3 polyunsaturated fatty acids (n-3 PUFA), lutein, vitamin E and selenium on microvascular function, oxidative stress and inflammatory mediators in patients after acute coronary syndrome (ACS).

Patients And Methods: In a prospective, randomized, interventional, double-blind clinical trial, ACS patients were assigned to either the Nutri4 (N=15, mean age: 57.2 ± 9.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to assess how bariatric surgery affects the way the body processes orally taken medications and supplements.
  • It analyzed data from 58 studies involving 1985 participants, focusing on specific drugs and supplements, and found that while some showed changes in pharmacokinetic (PK) parameters post-surgery, others did not.
  • The conclusion highlighted significant variability in study results, emphasizing the need for more research to establish effective practices for medication management after bariatric surgery.
View Article and Find Full Text PDF

Objective: The effectiveness of supragingival dental biofilm control during orthodontic treatment and changes in the bacterial profile were analyzed.

Design: Sixty-four participants aged 12-22 years (57% female) were included in the study. Participants underwent orthodontic treatment with fixed appliances and were randomly assigned to one of the three groups, which during a period of one month: (I) used chlorhexidine digluconate (CHX), (II) used high concentration of fluoride (F) gel and (III) performed standard oral hygiene.

View Article and Find Full Text PDF

We highlight the particular aspects of the stable gastric pentadecapeptide BPC 157 pleiotropic beneficial activity (not destroyed in human gastric juice, native and stable in human gastric juice, as a cytoprotection mediator holds a response specifically related to preventing or recovering damage as such) and its possible relations with neurotransmitter activity. We attempt to resolve the shortage of the pleiotropic beneficial effects of BPC 157, given the general standard neurotransmitter criteria, in classic terms. We substitute the lack of direct conclusive evidence (i.

View Article and Find Full Text PDF

Growth differentiation factor 15 (GDF-15) is a stress-induced cytokine associated with acute and chronic inflammatory states. This prospective observational study aimed to investigate the prognostic roles of GDF-15 and routine clinical laboratory parameters in COVID-19 patients. Upon the admission of 95 adult hospitalized COVID-19 patients in Croatia, blood analysis was performed, and medical data were collected.

View Article and Find Full Text PDF

The Impact of Vitamin Deficiencies on Oral Manifestations in Children.

Dent J (Basel)

April 2024

Department of Pathophysiology, Physiology and Immunology, Faculty of Dental Medicine and Health Osijek, J. J. Strossmayer University of Osijek, 31000 Osijek, Croatia.

Article Synopsis
  • * Specific vitamins like A, D, E, K, and B-complex play significant roles in maintaining oral health, supporting functions from enamel strength to blood clotting.
  • * Collaboration between dental professionals and caregivers is essential to address these deficiencies through supplementation and personalized dental care for better health outcomes in children.
View Article and Find Full Text PDF