16 results match your criteria: "Italy Hospital[Affiliation]"

Objectives: To evaluate the feasibility of the autoinflammatory disease activity index (AIDAI) as a tool to assess disease activity in patients with hereditary recurrent fever syndromes (HRFs) treated with canakinumab.

Methods: Patients with active colchicine-resistant familial Mediterranean fever (crFMF), mevalonate kinase deficiency (MKD), or tumor necrosis factor receptor-associated periodic syndrome (TRAPS) were enrolled in the phase III CLUSTER study and asked to complete the AIDAI questionnaire daily. All patients included in the analysis were treated with canakinumab, but regimens and periods of treatment varied per study protocol.

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Prevalence survey of healthcare-associated infections in a large teaching hospital.

Ann Ig

July 2020

Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy - Hospital Hygiene Unit, Policlinico Umberto I Hospital, Rome, Italy.

Background: Healthcare-associated infection (HAI) is the most frequent adverse event in healthcare settings. It is associated with increased mortality and antimicrobial resistance, leading to prolonged hospital stays and consistent financial loss for healthcare systems. The objective of this study was to estimate the burden of HAIs and antimicrobial use in the Teaching Hospital Policlinico Umberto I (THPUI) of Rome and to identify the most critical areas for intervention.

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e-Health and multiple sclerosis: An update.

Mult Scler

November 2018

Department of Medical, Surgical, Neurological, Metabolic and Aging Sciences, I Clinic of Neurology, University of Campania "Luigi Vanvitelli," Naples, Italy.

e-Health (or digital healthcare) is becoming increasingly relevant in multiple sclerosis (MS) clinical management. We aim to review and discuss current status and future perspective of e-health in people with multiple sclerosis (pwMS). The first part of this review describes how information on MS can be conveyed through the Web and digital media.

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: Cancer Registries (CRs) remain the gold standard for providing official epidemiological estimations. However, due to CRs' partial population coverage, hospitalization records might represent a valuable tool to provide additional information on cancer occurrence and expenditures at national/regional level for research purposes. The Epidemiology of Cancer in Italy (EPIKIT) study group has been built up, within the framework of the Civic Observers for Health and Environment: Initiative of Responsibility and Sustainability (COHEIRS) project under the auspices of the Europe for Citizens Program, to assess population health indicators.

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Clinical and epidemiological studies demonstrate that short- and long-term exposure to air pollution increases mortality due to respiratory and cardiovascular diseases. Given the increased industrialization and the increased sources of pollutants (i.e.

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We aimed to analyze bone mineralization and the effect of different risk factors for osteoporosis in postmenopausal women. We found 4909 postmenopausal subjects within ≥10,000 records from the ROIS/EMEROS (Ionian and Salento Osteoporosis Registry/Euro Mediterranean Registry of Osteoporosis) registry, a population study carried out in an area characterized by heavy environmental pressure between Brindisi and Taranto from 2009 to 2016. All subjects were assessed via phalangeal quantitative ultrasound (QUS) to evaluate their bone mineralization (assessed via amplitude dependent speed of sound (AD-SoS)) and the association between demineralization and the presence of other conditions or risk factors.

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Environment and Health: Not Only Cancer.

Int J Environ Res Public Health

July 2016

Southern Italy Hospital Institute (IOS), Medicina Futura Research, Naples 80143, Italy.

The Hippocratic tradition emphasized environmental causes of diseases and the need for harmony between the individual and the natural environment as the right philosophy to maintain a good health status. Public awareness and scientific attention concerning environmental pollution is usually focused on the consequent increased risk of developing cancer. Air pollution has been recognized by the World Health Organization (WHO) to cause cardiovascular and respiratroy diseases, as well as lung cancer, after acute/chronic exposure to fine particulates (PM2.

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Diabetes and bone: biological and environmental factors.

Curr Opin Endocrinol Diabetes Obes

December 2015

aIOS, Southern Italy Hospital Institute bColeman Ltd, Naples, cISBEM, Euro Mediterranean Scientific Biomedical Institute, Brindisi and Naples dUniversity Federico II, Naples, Italy.

Purpose Of Review: Type 1 and type 2 diabetes mellitus are known to increase fracture risk. It is known that type 1 diabetes mellitus is associated with lower bone mineral density, but for type 2 diabetes mellitus, the real risk of increasing osteoporotic fractures is not explained by bone mineral density, which was found to be normal or paradoxically higher than controls in several studies, thus claiming for further investigations. This review summarizes some of the newest findings about factors that contribute to bone alterations in diabetic patients.

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Objective: To assess the burden of regional environmental factors influencing the incidence of Melanoma in the Italian population and overcome the problem of partial population coverage by local cancer registries and thematic archives.

Methods: We analyzed the Italian national hospitalization records from 2001 to 2008 provided by the Ministry of Health, excluding hospital re-admissions of the same patients, in order to assess the occurrence of Melanoma over a 8-year period. Data were presented by age groups (absolute number of cases from 20 to ≥80 years old) and per Region (rates per 100,000 inhabitants) for each year.

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Illegal Dumping of Toxic Waste and Its Effect on Human Health in Campania, Italy.

Int J Environ Res Public Health

June 2015

National Research Council (CNR), ISPAAM, 80100 Naples, Italy.

The region of Campania (particularly Naples and Caserta) has experienced an emergency in the waste management cycle during past years. Although the most critical phase has been overcome after the construction of the incineration plant in Acerra (an old-fashioned technology built up over a few months, whose impact on environment and health has not yet been assessed), most of the underlying problems have not been resolved. The illegal burning of wheels, plastics, textiles, and other industrial residuals, along with the detection of two thousand toxic substance dumping sites, still represents major concerns of environmental pollution and population health.

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A global perspective on the outcomes of surgical decompression in patients with cervical spondylotic myelopathy: results from the prospective multicenter AOSpine international study on 479 patients.

Spine (Phila Pa 1976)

September 2015

*Department of Surgery, University of Toronto, Toronto, Ontario, Canada †Department of Surgery, Toronto Western Hospital, Toronto, Ontario, Canada ‡Department of Neurosurgery, University Hospital Catania, Catania, Italy §Hospital San Juan de Dios, Caracas, Venezuela ¶Department Neurosurgery, The University of Kansas, Kansas City ‖Department of Neurosurgery Radboud University, Nijmegen Medical Centre; Nijmegen, the Netherlands **Department of Neurosurgery, Beaumont Hospital, Dublin, Ireland ††Faculty of Medicine, University of Sao Paulo, Ribeirão Preto, Brazil ‡‡Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India §§Department of Neurosurgery, Hospital Santa Marcelina, Santa Marcelina, Brazil ¶¶Department of Neurosurgery, Università Politecnica Delle Marche, Ancona, Italy ‖‖Department of Orthopaedics, Tan Tock Seng Hospital, Singapore, Singapore ***Department of Orthopedic Surgery, Okayama University, Okayama, Japan †††Department of Orthopaedic Surgery, Teikyo University School of Medicine, Tokyo, Japan ‡‡‡Department of Orthopaedic Surgery, Chubu Rosai Hospital, Nagoya, Japan §§§Department of Orthopedics, Third Military Medical University, Chongqing, China ¶¶¶Department of Neurosurgery, Ege University, Izmir, Turkey; and ‖‖‖Department of Health Services, University of Washington, Seattle.

Study Design: Prospective, multicenter international cohort.

Objective: To evaluate outcomes of surgical decompression for cervical spondylotic myelopathy (CSM) at a global level.

Summary Of Background Data: CSM is a degenerative spine disease and the most common cause of spinal cord dysfunction worldwide.

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Objective: An increase in breast cancer incidence has been documented in Italy and in other countries, and some women decide by themselves to undergo diagnostic examinations outside the official screening campaigns. The aim of this paper was to analyze - in terms of effectiveness, appropriate access, and related costs - the path spontaneously followed by a sample of Italian women for the early diagnosis of breast cancer.

Subjects And Methods: A total of 143 women who consecutively referred themselves to the breast cancer outpatient facilities at the Sant'Andrea University Hospital in Rome from May to June 2007 were enrolled in the study, gave their consent, and were screened according to their individual risk factors for breast cancer.

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Type 2 diabetes mellitus (T2DM) is associated with a higher risk of fractures even in presence of normal or increased bone mineral density. The purpose of this three-year longitudinal study was to evaluate the risk of osteoporotic fractures by assessing the changes of Quantitative Ultrasound (QUS) parameters in a group of postmenopausal women with type 2 diabetes mellitus (T2DM) compared with non-diabetic controls. The measurements were taken on a group of 18 postmenopausal women affected by T2DM and 18 healthy age-matched controls, aged 55-70 years, referring to the Osteolab laboratory at the ISBEM Research Institute (Brindisi, Italy) between 2009 and 2013.

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Objective: Alendronate is a second generation bisphosphonate which has been widely used in medical practice for two decades to treat osteoporosis and prevent fragility fractures both in elderly people and in younger patients.

Methods: Since many papers have been recently published and new formulations or dosages have been developed, our aim was to review the most significant medical literature addressing the issues of efficacy, safety, posology and formulations of the treatment with alendronate in osteoporotic patients.

Results: The efficacy of alendronate in reducing the risk of vertebral and non-vertebral fractures has been demonstrated in several studies.

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The article describes the adaptation of a model to estimate the burden of postmenopausal osteoporosis in women aged 50 years and over in Italy between 2010 and 2020. For this purpose, a validated postmenopausal osteoporosis disease model developed for Sweden was adapted to Italy. For each year of the study, the 'incident cohort' (women experiencing a first osteoporotic fracture) was identified and run through a Markov model using 1-year cycles until 2020.

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In gastric carcinomas, including 20 cases of intestinal type and 10 cases of diffuse type, in adenomas with mild to severe dysplasia (20 cases), and in hyperplastic polyps (10 cases), the presence of lactoferrin was investigated by immunohistochemistry. Incomplete or complete intestinal metaplasia or both and normal gastric mucosa were also tested. Preoperative hematocrit and serum iron levels (18 patients) were recorded.

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