1,143,492 results match your criteria: "Italy; and Fraunhofer Institute for Translational Medicine and Pharmacology ITMP[Affiliation]"

Background: Intravascular ultrasound (IVUS) use in aortic endovascular interventions, including thoracic endovascular aneurysm repair (TEVAR) and endovascular aneurysm repair (EVAR), may have similar benefits to those seen in coronary and peripheral interventions, but limited utilization and outcome data exist.

Methods: Centers for Medicare and Medicaid Services claims data were used to identify patients undergoing TEVAR and EVAR from 2016 to 2023. Utilization trends were stratified by region, urbanicity, distressed communities index, community versus academic center, Medicare versus dual enrollment status, indication, urgency, and presence of dissection with malperfusion.

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Background: Lipoprotein(a) [Lp(a)] is associated with increased cardiovascular risk, but its influence on plaque characteristics at optical coherence tomography (OCT) evaluation is not fully understood.

Aims: This study seeks to explore the impact of Lp(a) levels on plaque morphology as assessed by OCT in a very high-risk subset of patients.

Methods: Consecutive patients admitted for acute coronary syndrome (ACS) and undergoing OCT-guided percutaneous coronary intervention (PCI) at a large tertiary care center between 2019 and 2022 were deemed eligible for the current analysis.

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Food leftovers can be used as alternative feed ingredients for monogastric to replace human-competing feedstuffs, such as cereals, recycle a waste product, reduce the feed-food competition and keep nutrients and energy in the feed-food chain. Among food leftovers, former food products (FFPs) are no more intended for human but still suitable for animal consumption. However, the metabolic impact of FFP has never been investigated.

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As rates of obesity rise worldwide, incidence of metabolic dysfunction-associated steatotic liver disease (MASLD), formerly referred to as nonalcoholic fatty liver disease, is increasing, worsening the burden of healthcare systems. The council of the Federation of International Societies for Pediatric Gastroenterology, Hepatology, and Nutrition (FISPGHAN) identified the topic of MASLD epidemiology, treatment, and prevention as a global priority issue to be addressed by an expert team, with the goal to describe feasible and evidence-based actions that may contribute to reducing MASLD risk. The FISPGHAN member societies nominated experts in the field.

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Gaslighting is an understudied form of psychological violence aimed to reduce victims' autonomy, decision-making ability, security, and belief in their own perceptions. Although it leads to negative psychological, relational, and health consequences, few studies have examined the protective variables of this form of violence. The present study aims to analyze the role of self-compassion and social support (from family, friends, and significant others) in predicting gaslighting experiences, psychological health, and eudaimonic well-being among young Italian women.

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Polyethylene (PE) is the most-produced polyolefin, and consequently, it is the most widely found plastic waste worldwide. PE biodegradation is under study by applying different (micro)organisms in order to understand the biodegradative mechanism in the majority of microbes. This study aims to identify novel bacterial species with compelling metabolic potential and strategic genetic repertoires for PE biodegradation.

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Background: Noonan syndrome (NS) is a rare group of autosomal genetic disorders. In recent years, with the exploration and development of molecular diagnostic techniques, more and more researchers have begun to pay attention to NS. However, there is still a lack of reports on the bibliometric analysis of NS worldwide.

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The construction industry is rapidly adopting Industry 4.0 technologies, creating new opportunities to address persistent environmental and operational challenges. This review focuses on how Artificial Intelligence (AI), Machine Learning (ML), and Deep Learning (DL) are being leveraged to tackle these issues.

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Editorial: Rare forms of pediatric adrenal disorders: beyond congenital adrenal hyperplasia due to 21-hydroxylase deficiency.

Front Endocrinol (Lausanne)

December 2024

Centre for Endocrinology, William Harvey Research Institute, Barts & the London School of Medicine & Dentistry, Queen Mary, University of London, London, United Kingdom.

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Corrigendum to "Investigating hormesis, aging, and neurodegeneration: From bench to clinics".

Open Med (Wars)

December 2024

Department of Environmental Health Sciences, Morrill I, N344, University of Massachusetts, Amherst, MA 01003, United States of America.

[This corrects the article DOI: 10.1515/med-2024-0986.].

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Value development over the life-span is rarely studied due to theory and data limitations. We use the LISS data, a Dutch longitudinal dataset, to study value change in adults aged 25-70 over 11 years from 2008 to 2019 (N=10,860), using the neo- socioanalyitcal model (NSM) as a theoretical framework. We find few cohort differences, differences between age groups and non-linear value change within individuals that continues until late adulthood.

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Introduction: Body awareness (BA) is the process of gaining sensory awareness based on the physiological states and actions of the body. It is influenced by an individual's attitudes, perceptions, beliefs, and experiences within the social and cultural contexts. Following a stroke, impairments in BA are thought to be widespread and could have a significant impact on recovery results.

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Collaborative intelligence (CI) involves human-machine interactions and is deemed safety-critical because their reliable interactions are crucial in preventing severe injuries and environmental damage. As these applications become increasingly data-driven, the reliability of CI applications depends on the quality of data, shaping the system's ability to interpret and respond in diverse and often unpredictable environments. In this regard, it is important to adhere to data quality standards and guidelines, thus facilitating the advancement of these collaborative systems in industry.

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Axillary lymph node dissection in breast cancer patients: obsolete or still necessary?

Lancet Reg Health Eur

December 2024

Breast Unit Policlinico Tor Vergata, Department of Surgical Science, Tor Vergata University, Viale Oxford 81, 00133, Rome, RM, Italy.

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Background: Orbital rhabdomyosarcoma (RMS) is often limited to the orbital cavity and has a favorable prognosis. In some cases, the tumor can erode the orbital bone and behave as a parameningeal RMS (PM-RMS); thus, it is treated more intensively. However, the current protocols do not provide any guidance on how to consider different grades of bone erosion (BE) that can vary widely, hampering a uniform classification and the subsequent treatment assignment.

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Background: Prior studies have reported lower effectiveness of XBB.1.5-adapted vaccines against hospitalization related to the Omicron JN.

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SUMO2 rescues neuronal and glial cells from the toxicity of P301L Tau mutant.

Front Cell Neurosci

December 2024

Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.

Introduction: Abnormal intracellular accumulation of Tau aggregates is a hallmark of Alzheimer's disease (AD) and other Tauopathies, such as Frontotemporal dementia (FTD). Tau deposits primarily affect neurons, but evidence indicates that glial cells may also be affected and contribute distinctively to disease progression. Cells can respond to toxic insults by orchestrating global changes in posttranslational modifications of their proteome.

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Developmental origins of natural sound perception.

Front Psychol

December 2024

Laboratoire des Systèmes Perceptifs, UMR CNRS 8248, Ecole Normale Supérieure, PSL University, Paris, France.

Infants are exposed to a myriad of sounds early in life, including caregivers' speech, songs, human-made and natural (non-anthropogenic) environmental sounds. While decades of research have established that infants have sophisticated perceptual abilities to process speech, less is known about how they perceive natural environmental sounds. This review synthesizes current findings about the perception of natural environmental sounds in the first years of life, emphasizing their role in auditory development and describing how these studies contribute to the emerging field of human auditory ecology.

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Recent research on social cures has posited that one's social identity associated with group membership can promote adjustment and affect well-being, especially for vulnerable individuals. In this study, we argue that, although the negative consequences of group-based stigma affect prisoners' well-being, having multiple social identities can protect them and mitigate the detrimental effects of stigma. The results of this cross-sectional study reveal that group identification with prisoners ( = 52) was negatively associated with well-being and anticipated discrimination.

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Introduction: Academic environments are known for their high demands, often resulting in significant distress among employees. Thus, identifying effective intervention strategies to mitigate workplace stress is essential. The present study aims to evaluate the potential benefits of mind-body interventions (i.

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Introduction: As the livestock industry grapples with the need for sustainable land, maintaining production systems, and reducing antimicrobial resistance, the application of functional nutrition emerges as a potential solution.

Aim: In line with the One Health principles, this study aims to evaluate functional properties of and and assess the effects of their dietary supplementation on piglets' health.

Materials And Methods: A chemical-functional characterization was conducted before and after digestion.

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In patients affected by anorexia nervosa (AN) different endocrine abnormalities have been described, but, among them, hypothalamic-pituitary-adrenal (HPA) dysfunction, although associated to important side effects, is underestimated and has no therapeutical options. We present a narrative literature review to investigate the HPA axis in patients with AN, in order to highlight HPA dysfunction and its effects. We also described the crucial role of HPA monitoring, and to consider eventual therapeutic and preventive strategies in AN patients.

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