40 results match your criteria: "Istituto Clinico Beato Matteo[Affiliation]"

Is Pulse Modulation the Future of Laser Technology in Endourology: Evidence from a Literature Review - Section of EAU Endourology.

Eur Urol Focus

November 2024

Division of Experimental Oncology/Unit of Urology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy; University Vita-Salute San Raffaele, Milan, Italy; Young Academic Urologists Endourology & Urolithiasis Working Group, European Association of Urology, Arnhem, The Netherlands; Progressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France. Electronic address:

Article Synopsis
  • The review aimed to evaluate the effects of pulse modulation technology on laser lithotripsy and prostate enucleation in endourology, focusing on efficiency, safety, and tissue interaction.
  • A systematic search of studies from the last 20 years identified 29 articles that examined these technologies, with preclinical studies showing promise in stone fragmentation but mixed results in clinical settings.
  • While pulse modulation can improve operational efficiency and reduce thermal safety risks, its benefits for prostate surgery outcomes remain inconsistent, yielding comparable rates to standard modalities in terms of stone-free status and complications.
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Background And Objective: The widespread adoption and rapid integration of new technologies and techniques in endoscopic and laser bladder interventions, particularly endoscopic enucleation, have led to new types of bladder injuries. This underscores the need for an intraoperative injury classification system. This study aims to develop and validate the Bladder Injury Classification System for Endoscopic Procedures (BICEP), which standardizes the classification of complications and intervention requirements.

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The aim of this study was to construct the sixth in a series of guidelines on the treatment of urolithiasis by the International Alliance of Urolithiasis (IAU) that by providing a clinical framework for the management of pediatric patients with urolithiasis based on the best available published literature. All recommendations were summarized following a systematic review and assessment of literature in the PubMed database from January 1952 to December 2023. Each generated recommendation was graded using a modified GRADE methodology.

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Purpose: We aim to report here the first clinical series of patients treated with AEEP using a novel hybrid thulium:yttrium-aluminium-garnet (Tm:YAG) laser generator (RevoLix HTL, LISA Laser Products, Germany), i.e. capable of emitting both in pulsated and continuous-wave.

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Purpose: To examine temporal-spatial distribution of heat generated upon laser activation in a bench model of renal calyx. To establish reference values for a safety distance between the laser fiber and healthy tissue during laser lithotripsy.

Methods: We developed an in-vitro experimental setup employing a glass pipette and laser activation under various intra-operative parameters, such as power and presence of irrigation.

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Purpose: Iatrogenic ureteral strictures (US) after endoscopic treatment for urolithiasis represent a significant healthcare concern. However, high-quality evidence on the risk factors associated with US is currently lacking. We aimed to develop a consensus statement addressing the definition, risk factors, and follow-up management of iatrogenic US after endoscopic treatment for urolithiasis.

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Purpose: The aim of this study is to prospectively evaluate whether individual and group Therapeutic Patient Education (TPE) can reduce the need to intensify treatment of diabetes and hypertension in newly diagnosed type 2 diabetic patients.

Methods: A total of 937 patients were recruited and followed-up for 42.7 ± 21.

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Purpose: We aimed to accurately determine ureteral stricture (US) rates following urolithiasis treatments and their related risk factors.

Methods: We conducted a systematic review and meta-analysis following the PRISMA guidelines using databases from inception to November 2023. Studies were deemed eligible for analysis if they included ≥ 18 years old patients with urinary lithiasis (Patients) who were subjected to endoscopic treatment (Intervention) with ureteroscopy (URS), percutaneous nephrolithotomy (PCNL), or shock wave lithotripsy (SWL) (Comparator) to assess the incidence of US (Outcome) in prospective and retrospective studies (Study design).

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Article Synopsis
  • The study explores how dietary patterns, specifically adherence to a Mediterranean diet, relate to muscle health and the risk of sarcopenia in adults over 50 in southern Italy.
  • Researchers analyzed data from 528 participants, measuring muscle strength with handgrip tests and estimating muscle mass through bioelectrical impedance, using a food frequency questionnaire to identify dietary habits.
  • Results revealed that stronger adherence to the Mediterranean diet was linked to better muscle strength and a lower risk of sarcopenia, with significant differences noted in handgrip strength between the highest and lowest adherent groups.
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Purpose: To identify laser settings and limits applied by experts during laser vaporization (vapBT) and laser en-bloc resection of bladder tumors (ERBT) and to identify preventive measures to reduce complications.

Methods: After a focused literature search to identify relevant questions, we conducted a survey (57 questions) which was sent to laser experts. The expert selection was based on clinical experience and scientific contribution.

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Article Synopsis
  • The study aims to gather laser lithotripsy settings from experts for different clinical situations and to identify ways to minimize complications.
  • A survey was conducted among laser specialists, revealing that the majority use Holmium-YAG lasers, with variations in settings for specific scenarios like middle-ureteral, pelvic, and lower pole stones.
  • Experts reported a general consensus on preferred techniques, with preventive measures like power limits and intermittent activation commonly employed to reduce thermal injury risks during procedures.
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Objective: Polyphenol intake may prevent hepatic steatosis and cardiovascular disease by potentially improving endothelial function. The purposes of this study are to investigate the association between fatty liver disease and endothelial dysfunction and to test the effects of a nutraceutical containing extracts made from Citrus bergamia and Cynara cardunculus on peripheral vascular endothelial function in adults with liver steatosis.

Methods: We analyzed data from 32 individuals with hepatic steatosis and endothelial dysfunction (reactive hyperemia index ≤ 1.

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Purpose: To highlight and compare experts' laser settings during endoscopic laser treatment of upper tract urothelial carcinoma (UTUC), to identify measures to reduce complications, and to propose guidance for endourologists.

Methods: Following a focused literature search to identify relevant questions, a survey was sent to laser experts. We asked participants for typical settings during specific scenarios (ureteroscopy (URS), retrograde intrarenal surgery (RIRS), and percutaneous treatment).

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What to expect from the novel pulsed thulium:YAG laser? A systematic review of endourological applications.

World J Urol

November 2023

Progressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France.

Introduction: Several preclinical studies about a novel pulsed-thulium:yttrium-aluminum-garnet (p-Tm:YAG) device have been published, demonstrating its possible clinical relevance.

Methods: We systematically reviewed the reality and expectations for this new p-Tm:YAG technology. A PubMed, Scopus and Embase search were performed.

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Purpose: To identify expert laser settings for BPH treatment and evaluate the application of preventive measures to reduce complications.

Methods: A survey was conducted after narrative literature research to identify relevant questions regarding laser use for BPH treatment (59 questions). Experts were asked for laser settings during specific clinical scenarios.

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Article Synopsis
  • The study investigates long-COVID, a complex condition with no effective treatments, particularly focusing on cardiovascular symptoms like high heart rate and palpitations linked to mast cell activation (MCA).
  • Researchers administered histamine receptor blockers (fexofenadine and famotidine) to 14 patients with long-COVID symptoms over 20 days and compared results with 13 control subjects.
  • Results showed that 29% of treated patients experienced complete symptom resolution, with significant improvements in all treated individuals, supporting the idea that targeting histamine receptors may be a viable treatment for long-COVID.
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Laparoscopic Pyelolithotomy for treating urolithiasis in ectopic pelvic kidneys.

Int Braz J Urol

November 2023

Division of Experimental Oncology/Unit of Urology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.

Introduction: The management of urolithiasis ectopic pelvic kidneys (EPK) can be challenging because of the aberrant anatomy (1-4). We demonstrate the step-by-step technique of the laparoscopic approach for treating urolithiasis in EPK.

Patients And Methods: Three men with EPK (2 left, 1 right) underwent laparoscopic pyelolithotomy through a transperitoneal approach.

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Introduction And Objectives: The use of ureteral access sheaths (UAS) limits the irrigation-induced increase in intrarenal pressure during ureteroscopy (URS). We investigated the relationship between UAS and rates of postoperative infectious complications in stone patients treated with URS.

Materials And Methods: Data from 369 stone patients treated with URS from September 2016 to December 2021 at a single institution were analyzed.

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Purpose: Microvascular disease (MVD) is associated with amputation linked to peripheral artery disease (PAD) in the general population. No study evaluated the impact of diabetic microvascular complications on the outcomes of vascular diabetic foot ulcers (DFU). The aim of the study was to investigate whether retinopathy, nephropathy, and polyneuropathy can predict the outcomes of DFU in type 2 diabetic patients with PAD.

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Objective: To analyze the pattern of speaker activity related to both flexible ureteroscopy (fURS) and percutaneous nephrolithotomy (PCNL) during plenary sessions at the main (endo)urological international meetings over the last 10 years.

Methods: We reviewed the meeting programs of the main endourological international meetings (EAU, AUA, WCE, and SIU) during 2011-2019. We detected all invited speakers at plenary sessions regarding fURS or PCNL.

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Association of erectile dysfunction with diabetic foot and its outcomes in type 2 diabetic men.

Hormones (Athens)

March 2023

Diabetes and Endocrine-Metabolic Diseases Unit, Istituto Clinico Beato Matteo, Gruppo Ospedaliero San Donato, Corso Pavia 84, 27029, Vigevano, Italy.

Purpose: Erectile dysfunction (ED) and diabetic foot (DF) are common complications in patients with diabetes. However, the relationship between ED and DF has been little studied. In particular, no study has evaluated whether ED is associated with the outcomes of DF.

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