Does Cognitive Impairment Affect Rehabilitation Outcome in Parkinson's Disease?

Background: The cognitive status is generally considered as a major determinant of rehabilitation outcome in Parkinson's disease (PD). No studies about the effect of cognitive impairment on motor rehabilitation outcomes in PD have been performed before.

Objective: This study is aimed to evaluate the impact of cognitive decline on rehabilitation outcomes in patients with PD.

New strategies in motor parkinsonism.

A satisfactory motor control can be achieved for many years in Parkinson's disease (PD). Clinical management is more complex when disease progresses and occurrence of motor fluctuations and dyskinesias negatively impacts on patients' quality of life. Mobility depends increasingly on levodopa peripheral bioavailability.

Identification of the 5T-12TG allele of the cystic fibrosis transmembrane conductance regulator gene in hypertrypsinaemic newborns.

Unlabelled: In order to increase knowledge of the pathogenic effect of the 5T-12TG allele of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, we evaluated its presence in 24 hypertrypsinaemic newborns with borderline sweat tests. Among 20 CFTR-identified alterations, the 5T-12TG haplotype was the second most frequent mutation (14.6%) over F508del.

[Occupational asthma due to cyanoacrylate: a case-report].

Background: An increased use of acrylic compounds is observed in different industries, home repairs and hobbies. These compounds are known to cause skin sensitisation, irritation of mucous membranes and bronchial asthma. Methyl cyanoacrylate is moderately likely to be a sensitizer, while ethyl cyanoacrylate might be a weak sensitizer.

[Sampling of airborne allergens: practical experience].

The availability of specific monoclonal and policlonal antibodies and the standardization of allergen extracts enables to quantify the exposure to airborne allergens in the domestic environment and at the workplace. In this article we report our experience coming from three studies based upon the measurement of airborne allergens in different environments. In a pharmaceutical factory we measured levels of laboratory animals allergens and evaluated the prevalence of sensitization to the same allergens among the workers.

[Methods and applications in the control of hypersensitivity in exposed occupational populations].

The aim of this work is to present a clinical questionnaire for epidemiological studies in occupational allergology. We have evaluated and tested the items of such a questionnaire, finding a good sensitivity and specificity in terms of identification of symptoms and a clinical approach to the patient. The questionnaire was blind tested by two specialists and their results were found to be concordant.