6,040 results match your criteria: "Istanbul University-Cerrahpasa[Affiliation]"

The impact of an online support group on patients' awareness of pregnancy-and lactation-induced osteoporosis.

BMC Pregnancy Childbirth

November 2024

Department of Physical Medicine and Rehabilitation, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Turkey.

Background: Pregnancy and lactation-induced osteoporosis (PLO) is a serious and rare condition, which causes substantial physical and emotional distress. The rarity of PLO highlights the importance of alternative information sources such as online patient groups. This study aims to explore the experiences of PLO among members of a WhatsApp patient group and to analyze how participation in the group impacts members' knowledge about their condition, psychological well-being, and healthcare decisions.

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BACKGROUND During the COVID-19 pandemic, strict feeding restrictions were implemented in many dialysis centers to minimize transmission between patients. This study aims to evaluate the effects of these feeding restrictions on dry weight, intradialytic hypotension (IDH), and dialysis adequacy in hemodialysis patients. MATERIAL AND METHODS In this retrospective single-center study involving 76 hemodialysis patients, data from 2 consecutive 6-month periods were analyzed: the first before the COVID-19 pandemic when intradialytic nutrition was supported, and the second during the pandemic when intradialytic nutrition was restricted.

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Article Synopsis
  • Kidney diseases are linked to aging and the effects of decreased estrogen due to ovarian senescence, leading to reduced kidney function and increased cardiometabolic risks that can result in chronic kidney disease (CKD).
  • CKD can negatively impact ovarian function in women during their reproductive years.
  • An individualized menopause management approach for women with CKD includes hormone therapy based on personal preferences and cardiovascular risks, lifestyle modifications, regular monitoring, and tailored guidance for those with additional health issues.
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  • - Niemann-Pick Type-C (NPC) disease can lead to serious neuropsychiatric issues, including catatonia, which doesn't always respond well to standard treatments like antipsychotics.
  • - A patient with adult-type NPC developed catatonia that persisted despite various medications, but improved significantly with electroconvulsive therapy (ECT).
  • - Combining ECT with lorazepam managed the catatonia, and adding lamotrigine led to full remission for eight months, suggesting lamotrigine's potential benefits in treating recurrent catatonia.
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Our study is aimed at examining the Ice Hockey National Team players with regard to ACE I/D (rs1799752), ACTN3 (rs1815739), PPARA (rs4253778) and HIF1A (rs11549465) polymorphisms and physical tests. This study was participated by 21 players from ice hockey national team. While ACE I/D (rs1799752) polymorphism was obtained using conventional polymerase chain reaction method (PCR), ACTN3 (rs1815739), PPARA (rs4253778) and HIF1A (rs11549465) polymorphisms were produced by real time polymerase chain reaction method (qPCR).

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Background: Endovascular treatments are frequently applied in pelvic venous disorders (PeVDs) with guidelines recommendations. There is no clear answer as to which of the embolization methods applied with endovascular treatments is superior. In this study, we aimed to compare the outcomes and symptom relief of patients with PeVDs treated using coils alone versus those treated with both coils and ethylene vinyl alcohol copolymer, as well as to evaluate the material usage and safety and efficacy of these treatments.

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Article Synopsis
  • The study evaluated how renal tumor biopsy (RTB) impacted the success of trifecta criteria in patients who underwent open partial nephrectomy (OPN) for renal cancer from 2012 to 2023.
  • Out of 167 patients, trifecta achievement rates were similar between the RTB group (53.3%) and the non-RTB group (54.76%), indicating no significant difference in surgical outcomes.
  • However, the RTB group showed a higher incidence of lymphovascular invasion, suggesting that while RTB is safe, it may be associated with some negative pathology outcomes.
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Valproic acid (VPA) is a well-known and increasingly documented antiepileptic drug that has been widely used in the treatment of epilepsy and/or epilepsy-related disorders. Prolonged clinical use of VPA has been reported to cause side effects such as nephrotoxicity. Edaravone (EDA) is a powerful free radical scavenger.

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Non-Isothermal Crystallization Kinetics and Properties of CaO-AlO-SiO (CAS) Glass-Ceramics from Eggshell Waste, Zeolite, and Pumice.

Materials (Basel)

November 2024

Metallurgy and Materials Engineering Department, Engineering Faculty, Esentepe Campus, Sakarya University, 54187 Sakarya, Türkiye.

Article Synopsis
  • This study examines the properties and behavior of glass-ceramics made from eggshell waste, zeolite, and pumice, focusing on how crystallization occurs during heating.
  • X-ray diffraction (XRD) showed different crystalline phases forming at varying sintering temperatures, with changes in crystal shapes observed through scanning electron microscopy (SEM).
  • The research also analyzed crystallization activation energy and Avrami parameters, finding that the porosity in the materials influenced their hardness and density, with optimal properties noted at a sintering temperature of 1000 °C for one of the glass-ceramic compositions.
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Dysfunction of PTEN-Associated MicroRNA Regulation: Exploring Potential Pathological Links in Type 1 Diabetes Mellitus.

Medicina (Kaunas)

October 2024

Department of Internal Medicine, Kanuni Sultan Suleyman Training and Research Hospital, Health Sciences University, Istanbul 34668, Türkiye.

Type 1 Diabetes Mellitus (T1DM) is an autoimmune disease with T cell-mediated pathogenesis of pancreatic β-cell destruction, leading to insulin deficiency. MicroRNAs such as miR-223 and miR-106b, along with PTEN, have been reported to participate in the pathophysiology of diabetes and its complications. The current study has explored the expression of miR-223, miR-106b, and PTEN and their association with various clinical and biochemical parameters in subjects diagnosed with T1DM.

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Background: Presence of pes planus is known to effect balance. In this study, it was aimed to examine the immediate effects of IASTM and PMT on static and dynamic balance in young adults with pes planus.

Method: The navicular drop test was used to diagnose pes planus.

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Relation of functional independence to balance, exercise capacity, and peripheral muscle strength in individuals with chronic stroke: A cross-sectional study.

J Bodyw Mov Ther

October 2024

Department of Physiotherapy and Rehabilitation, Division of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Istanbul University-Cerrahpasa, Istanbul, Turkey. Electronic address:

Purpose: This cross-sectional study determined the relationship between functional independence and balance, functional exercise capacity, and knee extensor strength in individuals with chronic stroke.

Material And Methods: The study included fifty-four individuals with chronic stroke. A single physiotherapist evaluated clinical features.

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Effects of connective tissue massage and kinesiotaping in patients with fibromyalgia.

J Bodyw Mov Ther

October 2024

Department of Physiotherapy and Rehabilitation, Faculty of Health Science, Yeditepe University, Istanbul, Turkey. Electronic address:

Article Synopsis
  • Fibromyalgia (FM) is a painful condition without a standard treatment plan, and this study investigates how connective tissue massage (CTM) and kinesiotaping (KT) impact pain, depression, and quality of life for FM patients.
  • The study involved 34 FM patients divided into two groups, with one group receiving CTM and the other receiving KT, alongside regular electrotherapy over four weeks.
  • Results showed that both therapies significantly improved pain, depression, and overall quality of life, with no significant difference in effectiveness between the two treatments.
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Estimation of Height at Withers Based on Long Bone Measurements of Living Cats.

Vet Sci

October 2024

Osteoarchaeology Practice and Research Centre & Department of Anatomy, Faculty of Veterinary Medicine, Istanbul University-Cerrahpaşa, 34320 Avcılar, Türkiye.

In this study, coefficients enabling estimation of shoulder height were obtained by taking morphometric measurements from radiographic images of live cats using the radiogrammetric method. For this purpose, a total of 37 adult cats, including 17 females and 20 males, were involved. While the effect of sexual dimorphism was observed on the morphometric data, the presence of sexual dimorphism was only evident in the coefficients (factors) of the humerus and talus.

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Managing locally advanced, or metastatic radioactive iodine-refractory differentiated thyroid cancers (RAIR-DTC) poses substantial challenges, with few available treatment options. The aim of this study was to evaluate clinical outcomes of patients receiving sorafenib as first line treatment. In addition, prognostic markers affecting progression-free survival (PFS) were identified.

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The absence of a Food and Drug Administration-approved percutaneous valve technology for the treatment of severe aortic regurgitation (AR) presents a challenge for high-risk patients. In this report, we describe the successful treatment of an 84-year-old male patient suffering from severe symptomatic AR and concomitant cardiorenal syndrome with renal failure using a 34 mm Evolut R (Medtronic) self-expanding transcatheter aortic valve replacement. This intervention resulted in the resolution of AR, cardiorenal syndrome, and congestive heart failure symptoms.

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Tricine-modified chitosan as a strategy for enhancing hydrophilicity and gene delivery.

Carbohydr Res

January 2025

Istanbul University-Cerrahpaşa, Faculty of Engineering, Department of Chemical Engineering, Istanbul, Türkiye. Electronic address:

In this study, we investigated the effect of chitosan modification with tricine on transfection efficiency by preserving its ability to form complexes with plasmid DNA (pDNA) and increasing its hydrophilicity. The inherent limitations of chitosan, such as poor solubility at physiological pH, insufficient cellular uptake, and strong ionic interactions with pDNA, typically result in low transfection efficiency. To overcome these challenges, Tricine, a hydrophilic molecule containing a secondary amine group, was conjugated to chitosan.

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Introduction: Tobacco companies use social media to bypass marketing restrictions. Studies show that exposure to tobacco promotion on social media influences subsequent smoking behavior, yet it is challenging to monitor such content. We developed an artificial intelligence that can automatically identify tobacco-promoting content on social media.

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Secondary lymphoid organs (SLOs) provide the confined microenvironment required for stromal cells to interact with immune cells to initiate adaptive immune responses resulting in B cell differentiation. Here, we studied three patients from two families with functional hyposplenism, absence of tonsils, and complete lymph node aplasia, leading to recurrent bacterial and viral infections. We identified biallelic loss-of-function mutations in encoding the lymphotoxin beta receptor (LTβR), primarily expressed on stromal cells.

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Objectives: Academic self-efficacy (ASE), as well as self (SA) and peer assessment (PA), is associated with the subjective judgements of the individual. The correlation among these concepts merits further research. This study aims to examine the correlation between nursing students' attitudes towards ASE and SA and PA.

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