6,040 results match your criteria: "Istanbul University-Cerrahpasa[Affiliation]"
25th National and 11th International Annual Congress on Research and Technology of Iranian Medical Sciences Students, Urmia, Iran, 5-7 September, 2024.
Iran Biomed J
December 2024
Department of Nursing, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Formulation of nasal analgesic sprays with diclofenac sodium, ibuprofen, paracetamol, and evaluation of toxicity.
Sci Prog
December 2024
Department of Otorhinolaryngology, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.
Objective: Intranasal analgesic sprays represent a safe, efficacious method for pain relief, with a shorter working time compared to oral painkillers. This study aimed to develop nasal sprays using commonly available over-the-counter analgesics, providing an alternative treatment option that is more convenient and potentially more effective in managing pain, particularly in pediatric patients.
Methods: Three different nasal spray formulations with the contents of diclofenac sodium, ibuprofen, and paracetamol were created, and characterization studies were completed.
Antimicrobial and Antibiofilm Activity of Green Synthesized Silver Nanoparticles by Using In Vitro Grown Aloe vera L.
Microsc Res Tech
December 2024
Faculty of Science, Department of Molecular Biology and Genetics, Istanbul University, Istanbul, Turkey.
In this study, in vitro grown Aloe vera L. tissues were used for AgNP synthesis. Adventitious root and callus tissues were grown in MS medium containing 1 mg/L IAA and 1 mg/L NAA.
View Article and Find Full Text PDFAssociations between stages of diabetic polyneuropathy and quality of life, neuropathic pain, and well-being: A multicenter, cross-sectional analysis based on electroneuromyographic findings.
Neurophysiol Clin
December 2024
Department of Neurology, SANKO University School of Medicine, Gaziantep, Türkiye.
Aim: This study aimed to investigate the relationship between electrophysiological findings of diabetic neuropathy (DN) and patients' quality of life, neuropathic pain levels, and well-being.
Materials And Methods: A cross-sectional study was conducted in 12 centers in Turkey. DN patients were categorized into four stages based on electrophysiological findings using the Baba classification.
Utilization of AI - reshaping the future of food safety, agriculture and food security - a critical review.
Crit Rev Food Sci Nutr
December 2024
Independent Researcher, Germany.
Article Synopsis
Cisplatin- or Carboplatin-Based Chemotherapy Plus Pembrolizumab in Advanced Urothelial Cancer: Exploratory Analysis From the Phase 3 KEYNOTE-361 Study.
Clin Genitourin Cancer
November 2024
Division of Medical Oncology, Department of Internal Medicine, Cerrahpaşa Faculty of Medicine, Istanbul University-Cerrahpaşa, Istanbul, Türkiye.
Introduction: KEYNOTE-361 evaluated first-line pembrolizumab with and without platinum-based chemotherapy versus chemotherapy alone in advanced or metastatic urothelial carcinoma. The primary end points of progression-free survival (PFS) or overall survival (OS) were not met. Exploratory analysis of efficacy by platinum agent (cisplatin or carboplatin) is reported.
View Article and Find Full Text PDFThe Effects of Robot-Asssissted Gait Training on Balance and Fear of Falling in Patients with Stroke: A Randomized Controlled Clinical Trial.
Am J Phys Med Rehabil
December 2024
Department of Physical Medicine and Rehabilitation, Istanbul Beykent University, Faculty of Medicine, Istanbul, Turkey.
Article Synopsis
- This study compared the effects of Combined Training (CombT), which includes Robot-Assisted Gait Training and Traditional Balance Training (TBT), against TBT alone on improving balance and reducing fear of falling (FoF) in stroke patients.
- Patients were divided into two groups, with each group undergoing treatment for 5 weeks, and their balance and FoF were measured using several assessments, including the Berg Balance Scale and Timed Up and Go Test.
- Results showed CombT significantly improved balance and reduced FoF better than TBT alone, although TBT had its own notable improvements in limb impairment assessment.
Evaluation of Foveal Hypoplasia in Children with a History of Retinopathy of Prematurity.
Retina
December 2024
Department of Ophthalmology, Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey.
Purpose: To evaluate the foveal development in patients diagnosed with retinopathy of prematurity (ROP) and to evaluate whether foveal development was affected by treatment in ROP patients.
Methods: This cross-sectional study included patients with a history of ROP. Foveal development was compared between eyes with spontaneous regression and treated eyes.
Surgical approach to pulmonary metastases and its impact on prognosis.
Adv Clin Exp Med
December 2024
Department of General Surgery, Istanbul Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Background: Pulmonary metastasectomy (PM) is an important procedure for the treatment of metastatic nodules in the lung. The choice of surgical approach, whether thoracotomy or video-assisted thoracoscopic surgery (VATS), remains controversial in terms of the impact on patient prognosis.
Objectives: This study aimed to evaluate the outcomes and impact on survival of patients undergoing PM with VATS compared to thoracotomy.
Unusual synchronous and metachronous association of hematologic neoplasms with gynecologic neoplasms: A case series and literature review.
Int J Gynaecol Obstet
December 2024
Department of Internal Medicine, Division of Hematology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Article Synopsis
Enhanced supercapacitor performance with CZTS-based carbon nanocomposites electrodes: An electrochemical study.
J Colloid Interface Sci
November 2024
Department of Chemical Engineering, Bogazici University, TR-34342, Istanbul, Turkey; TUBITAK Marmara Research Center, Material Institute, Gebze 41470, Turkey. Electronic address:
Article Synopsis
- - The research highlights the urgent demand for effective energy storage solutions, leading to the development of a new composite material, CuZnSnS (CZTS) integrated with functionalized Multi-walled Carbon Nanotubes (f-MWCNT) using a hydrothermal method.
- - Three nanocomposite variants (CZTS (10), CZTS (20), CZTS (40)) were produced with different percentages of f-MWCNT, and the CZTS (20) sample showed the best electrochemical performance with a specific capacitance of 171F/g.
- - The study reveals that the CZTS/f-MWCNT nanocomposite retains 99% of its capacity after 3000 cycles, indicating its strong potential for enhancing
The effect of fatigue, sleep quality and depression on quality of life in patients with multiple sclerosis: A serial mediation model.
Mult Scler Relat Disord
December 2024
Ondokuz Mayis University, Faculty of Medicine, Department of Neurology, Samsun, Türkiye.
Article Synopsis
- Fatigue, depression, and sleep issues are common symptoms in patients with multiple sclerosis (PwMS) and significantly affect their quality of life, which was the focus of this study.
- The study included 178 PwMS and used various scales to assess fatigue, sleep quality, depression, and overall quality of life, analyzing the relationships between these factors.
- Results indicated that higher depression scores led to poorer sleep quality and greater fatigue, both of which negatively impacted physical and mental health aspects of quality of life in PwMS.
Author Correction: Achieving bifacial photovoltaic performance in PTB7-based organic solar cell by integrating transparent contact for emerging semi-transparent applications.
Sci Rep
December 2024
Department of Photonics, Faculty of Applied Sciences, Gazi University, Ankara, TR-06500, Türkiye, Turkey.
Synthesis, cytotoxicities, structural properties and comparison of dihalogeno-substituted-thiosemicarbazone ligands and mixed-ligand Ni(II) complexes.
Dalton Trans
December 2024
Department of Chemistry, Engineering Faculty, Inorganic Chemistry Department, Istanbul University-Cerrahpasa, 34320, Istanbul, Turkiye.
Article Synopsis
- * The complexes were analyzed and characterized through various techniques, including single-crystal X-ray diffraction, revealing a distorted square planar geometry with specific ligand interactions.
- * Cytotoxicity tests showed that the chloro-complex exhibited greater effectiveness against a leukemia cell line compared to the chemotherapy drug cisplatin, while being less toxic to healthy cells.
Exploring the potential and limitations of artificial intelligence in animal anatomy.
Ann Anat
December 2024
Laboratory of Veterinary Anatomy, Faculty of Veterinary Medicine, Istanbul University- Cerrahpasa, Turkey.
Article Synopsis
Ruxolitinib treatment ameliorates clinical, immunologic, and transcriptomic aberrations in patients with STAT3 gain-of-function disease.
J Allergy Clin Immunol
December 2024
Division of Pediatric Allergy and Immunology, Faculty of Medicine, Marmara University, Istanbul, Turkey; Istanbul Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Istanbul, Turkey; Isil Berat Barlan Center for Translational Medicine, Istanbul, Turkey. Electronic address:
Article Synopsis
- STAT3 gain-of-function disease causes issues like immune system overactivity and growth problems, but long-term treatment with the JAK inhibitor ruxolitinib has shown promise in symptom relief.
- The study monitored clinical and immune responses of four patients over a year, noting significant changes in T cell populations and the normalization of blood cell profiles, which were previously dysregulated.
- Ruxolitinib treatment not only managed symptoms but also modified harmful immune cell characteristics and reduced certain auto-reactive T-cell clones, suggesting a potential pathway to better control the disease's impact.
Stakeholder perspectives on graduates' acquisition of competencies in nursing bachelor's degree programs: A qualitative study.
Nurse Educ Today
November 2024
Istanbul Topkapi University, Department of Medical Services and Techniques, Istanbul, Turkey. Electronic address:
Article Synopsis
Corrigendum to "Re-examining the characteristics of pediatric multiple sclerosis in the era of antibody-associated demyelinating syndromes" [Europ. J. Paediatr. Neurol. 41 (2022) 8-18 doi.org/10.1016/j.ejpn.2022.08.006].
Eur J Paediatr Neurol
December 2024
Hacettepe University Faculty of Medicine, Department of Pediatrics, Division of Pediatric Neurology, Ankara, Turkey.
Fetal hypoplastic left heart syndrome: key factors shaping prognosis.
J Perinat Med
December 2024
Department of Pediatric Cardiology, İstanbul University-Cerrahpaşa School of Medicine, Istanbul, Türkiye.
Article Synopsis
Alu-Mediated Deletion of FANCA in Turkish Families With Fanconi Anemia: Evidence of a Founder Effect.
Am J Med Genet A
December 2024
Department of Medical Genetics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Article Synopsis
- Fanconi anemia (FA) is a genetic disorder that leads to bone marrow failure, causing low blood cell counts and increased cancer risk, along with various physical abnormalities.
- A study identified a specific genetic mutation, a large deletion in the FANCA gene, as a common cause among eight individuals from six unrelated Turkish families, highlighting the importance of genetic research in understanding the disease.
- The researchers developed a simple PCR test for this mutation, facilitating accurate diagnosis and genetic counseling for affected individuals and their families, especially in the Turkish population.
Surgical treatment of thymic epithelial tumor and myasthenia gravis.
Front Surg
November 2024
Department of Thoracic Surgery, Istanbul University-Cerrahpaşa, Cerrahpaşa Medical Faculty, Istanbul, Türkiye.
Article Synopsis
- * Thymomas grow slowly and are localized, while thymic carcinomas grow quickly and can spread, with respective 5-year survival rates of 78% and 30%.
- * Treatment depends on tumor resectability, starting with surgery for early-stage cases, followed by chemotherapy for more advanced stages, while conditions like myasthenia gravis are associated with these tumors and can be treated through various methods, including extended thymectomy.
Breast Cancer Recurrence in Initially Clinically Node-Positive Patients Undergoing Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in the NEOSENTITURK-Trials MF18-02/18-03.
Ann Surg Oncol
December 2024
Department of General Surgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Türkiye.
Article Synopsis
Junctional Ectopic Tachycardia After Congenital Heart Surgery: Incidence, Risk Factors, and Outcomes.
Turk Kardiyol Dern Ars
December 2024
Department of Pediatric Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul, Türkiye.
Article Synopsis
Factors influencing the prescription of add-on long-acting muscarinic antagonists in real-world asthma management: Insights from a national registry.
Respir Med
November 2024
Ankara University School of Medicine, Department of Chest Disease, Division of Immunology and Allergy, Ankara, Turkey.