568 results match your criteria: "Istanbul Prof. Dr. Cemil Taşcıoğlu City Hospital[Affiliation]"

Aim: This study aimed to investigate the relationship between PET and CT parameters and sarcopenia, adipose tissue, and tumor metabolism in esophageal carcinoma(EC) and its impact on survival in EC.

Method: Our study included 122 EC patients who underwent PET/CT for staging. Muscle and adipose tissue characteristics were evaluated, including lumbar(L3) and cervical(C3) muscle areas, psoas major(PM) and sternocleidomastoid muscle(SCM) parameters, and PET parameters for visceral and subcutaneous adipose tissue(SAT).

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Objective: Overexpression of Human Epidermal Growth Factor Receptor 2 (HER2) is thought to be more aggressive in gastric cancer. This study aimed to evaluate the predictability of HER2 status and other prognostic pathologic parameters using [F]FDG PET/CT and to investigate its impact on survival.

Methods: Pretreatment metabolic parameters measured by [F]FDG PET/CT as a prognostic factor were retrospectively evaluated in 117 HER2-analysed patients.

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Experience with salbutamol treatment in a family with congenital myasthenia due to CHRNE mutation.

Clin Neurophysiol

December 2024

Suna and Inan Kıraç Foundation, Neurodegeneration Research Laboratory, NDAL-KUTTAM, School of Medicine, Koc University, Istanbul, Turkey. Electronic address:

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Purpose: To determine the anatomical parameters of puncta in Turkish population without any complaint of epiphora, using anterior segment optic coherence tomography (AS-OCT).

Materials And Methods: The healthy participants between 26 and 83 years old who applied to our outpatient clinic from May 2022 to June 2022 for spectacle prescription or the accompanying person of the patients were included in the study. All participants underwent AS-OCT (Revo 60, OPTOPOL Technology, Zawiercie, Poland).

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Objective: Intracranial hemangiopericytomas (HPC) are rare tumors. Radiotherapy (RT) is frequently performed after surgery, depending on tumor size, location, and the type of resection. Moreover, RT is preferred as an effective treatment for local recurrence and metastasis.

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Background: Chatbots produced by artificial intelligence are frequently used in health information today. We aimed to investigate the reliability and reproducibility of the answers given by Chat Generative Pretrained Transformer (ChatGPT), one of the most used chatbots, to frequently asked questions related to chronic kidney failure.

Methods: We reviewed frequently asked questions related to chronic kidney disease (CKD) from social media platforms and Internet.

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Background: The aim of this study is to determine the effect of Korean hand acupressure applied after thyroidectomy on postoperative pain, nausea, vomiting, and retching of number and severity.

Materials And Methods: The type of study is a randomized study with a post-test-control group. The protocol was prepared according to the SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) 2013 checklist.

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Introduction: To evaluate the effect of fractionation and prognostic factors on local control (LC) in the treatment of vestibular schwannoma (VS).

Methods: The medical records of 104 patients with vestibular schwannoma who were treated with stereotactic radiosurgery (SRS) from January 2015 to September 2023 were retrospectively collected. SRS was performed using Cyberknife robotic lineer accelerator.

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Introduction Tracheal intubation is a high-risk airway management protocol frequently applied in patients with critical illnesses. Numerous parameters have been suggested to predict mortality in these patients. Blood gas analysis, electrolyte levels, enzyme activities, and other biochemical measurements provide insights into a patient's metabolic status and organ functions.

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Ultrahigh-resolution 7-Tesla anatomic magnetic resonance imaging and diffusion tensor imaging of formalin-fixed human brainstem-cerebellum complex.

Front Hum Neurosci

November 2024

The Loyal and Edith Davis Neurosurgical Research Laboratory, Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ, United States.

Introduction: Brain cross-sectional images, tractography, and segmentation are valuable resources for neuroanatomical education and research but are also crucial for neurosurgical planning that may improve outcomes in cerebellar and brainstem interventions. Although ultrahigh-resolution 7-Tesla (7T) magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) reveal such structural brain details in living or fresh unpreserved brain tissue, imaging standard formalin-preserved cadaveric brain specimens often used for neurosurgical anatomic studies has proven difficult. This study sought to develop a practical protocol to provide anatomic information and tractography results of an human brainstem-cerebellum specimen.

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Objectives: Many people who are rescued alive from rubble after earthquakes suffer from crush injuries and associated acute kidney injury (AKI). McMahon score is used to determine the risk of AKI and mortality due to rhabdomyolysis in hospitalized patients. In this study, we aimed to evaluate the clinical findings, biochemical characteristics, and outcomes of crush injury patients admitted to our tertiary hospital and the use of the McMahon score in determining the need for renal replacement therapy (RRT) in this patient group.

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Risk of Spreading in Adult-onset Dystonia.

Tremor Other Hyperkinet Mov (N Y)

December 2024

Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Neurology, Istanbul, Turkey.

Background: Adult-onset dystonia can also spread to other parts of the body, although it is not as common as childhood-onset dystonia.

Objective: Our study aimed to examine the clinical factors determining spreading patterns in all adult-onset dystonia types.

Methods: We retrospectively analyzed the medical records of patients with a diagnosis of isolated dystonia followed longitudinally at our center.

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Since the first successful use of cardiopulmonary bypass (CPB), much has changed in its technology, area of use, and management. Despite suggestions in guidelines, the institutional behavior may change based on institutional experience and established habits. This so-called "deviation" may alter management strategies in favorable or unfavorable ways.

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Background: This study aimed to present our experience with transcatheter pulmonary debanding, focusing on patient outcomes.

Methods: The retrospective study was conducted with 32 patients (17 males, 15 females; mean age: 3.6±2 years; range, 0.

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Article Synopsis
  • The study investigates Elabela as a potential laboratory marker for predicting placenta previa and placenta accreta, two serious obstetric conditions that currently lack biochemical diagnostic tools.
  • Conducted between 2020 and 2022 at two tertiary centers, the research analyzed Elabela levels in groups with plancental anomalies, finding significant differences in Elabela levels among control, previa, and accreta groups.
  • Results indicated a promising cut-off value for Elabela in diagnosing both conditions, with sensitivity and specificity showing potential for Elabela to be used as a biochemical marker, encouraging further research in this area.
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BACKGROUND Cartilage injuries are challenging to treat due to limited self-healing. Standard treatments often lead to the formation of less durable fibrocartilage. Caffeic acid phenethyl ester (CAPE), a polyphenolic compound, can improve cartilage repair.

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Article Synopsis
  • Dual antiplatelet therapy (DAPT) is essential for managing acute and chronic coronary syndromes, helping to lower mortality rates and prevent further complications.
  • A study followed 1500 patients on a specific fixed-dose DAPT (ASA + clopidogrel) to evaluate its effectiveness and safety, primarily focusing on hospitalization and bleeding risks.
  • Results indicated that the fixed-dose combination therapy was effective, with low rates of hospitalization for cardiovascular issues and minimal bleeding complications in appropriately selected patients.
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Background: Endovascular treatments are frequently applied in pelvic venous disorders (PeVDs) with guidelines recommendations. There is no clear answer as to which of the embolization methods applied with endovascular treatments is superior. In this study, we aimed to compare the outcomes and symptom relief of patients with PeVDs treated using coils alone versus those treated with both coils and ethylene vinyl alcohol copolymer, as well as to evaluate the material usage and safety and efficacy of these treatments.

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Article Synopsis
  • The study aimed to evaluate the quality and readability of websites about Piriformis Syndrome by analyzing the top 200 results from a Google search.
  • Out of 138 websites assessed, 39 were deemed high-quality, primarily from scientific and health portals, but there was no significant difference in overall readability between high and low-quality sites except for specific readability scores.
  • The content analysis revealed that scientific websites provided more information about diagnosis, while non-profit sites discussed surgical options the most, highlighting varying content approaches among different types of websites.
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Purpose: This study aims to evaluate the effectiveness of two prophylactic strategies in preventing shunt infections in pediatric patients undergoing ventriculoperitoneal shunt surgery.

Methods: This retrospective study included pediatric patients who underwent ventriculoperitoneal shunt surgery between 2017 and 2024. Patients were divided into two groups based on the prophylactic method used: Group 1 (VS) where the shunt was washed with vancomycin solution before placement, and Group 2 (TVP) where vancomycin powder was applied to the subgaleal and subcutaneous tissues after shunt placement.

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Retrospective analysis of hemophilia B in Turkey: identifying main characteristics and treatment options.

Res Pract Thromb Haemost

October 2024

Department of Internal Medicine, Division of Hematology, Istanbul University - Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, Turkey.

Background: Hemophilia B (HB), an X-linked recessive inherited bleeding disorder, exhibits a high prevalence among males.

Objectives: To present the first national cohort of persons with HB to define the demographics, clinical characteristics, and treatment patterns in Turkey.

Methods: This multicenter, retrospective study included 433 alive persons with HB registered in 35 centers between 1961 and 2018.

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Background: Food allergy is a public health issue that has a significant impact on the lives of families. Parental self-efficacy/confidence is important in managing food allergies. The aim of this study is to validate the "Food Allergy Self-Efficacy Scale for Parents" (FASE-P) and assess parental self-efficacy in managing their child's food allergy.

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Article Synopsis
  • - In recent years, multipotent mesenchymal stromal cells (MSCs) have emerged as a potential therapy for lung regeneration in preterm infants, suggesting their use could also benefit conditions like pulmonary hypoplasia seen in congenital diaphragmatic hernia.
  • - A case study highlighted a newborn with a left congenital diaphragmatic hernia who received two MSC treatments, resulting in improved respiratory function and nutrition without any side effects.
  • - While MSC therapy shows promise for addressing pulmonary hypoplasia and intestinal issues related to congenital diaphragmatic hernia, further research is needed to understand side effects, optimal dosages, and administration techniques.
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Background: Diagnosing anaphylaxis in children within the first 2 years of life can be difficult due to the often confusing and nonspecific signs and symptoms.

Objective: This study focuses on the phenotype of anaphylaxis in children within the first 2 years of life and aims to increase awareness of anaphylaxis in this age group.

Methods: The study included children between 0 and 2 years who were diagnosed as having anaphylaxis by pediatric allergists in 11 tertiary hospitals.

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