2,779 results match your criteria: "Istanbul Okmeydanı Research and Training Hospital[Affiliation]"

LesionScanNet: dual-path convolutional neural network for acute appendicitis diagnosis.

Health Inf Sci Syst

December 2025

Section for Fisheries Technology, Institute of Aquatic Resources, DTU Aqua, Technical University of Denmark, 9850 Hirtshals, Denmark.

Acute appendicitis is an abrupt inflammation of the appendix, which causes symptoms such as abdominal pain, vomiting, and fever. Computed tomography (CT) is a useful tool in accurate diagnosis of acute appendicitis; however, it causes challenges due to factors such as the anatomical structure of the colon and localization of the appendix in CT images. In this paper, a novel Convolutional Neural Network model, namely, LesionScanNet for the computer-aided detection of acute appendicitis has been proposed.

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Atrial fibrillation (AF) is the most common cardiac dysrhythmia and a common cause of ischemic stroke. Stroke prevention with oral anticoagulation (OAC) is the cornerstone of AF management. Patients and their treating physicians may have different views on different attributes of OACs.

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The holmium laser enucleation of the prostate (HoLEP) is a widely accepted and reliable treatment for benign prostatic hyperplasias. In developing countries where HoLEP surgery has only recently been introduced, its popularity is steadily increasing. In our case, the patient's history of HoLEP and the image of the irregular mass extending from the anterior bladder wall into the lumen were initially misdiagnosed as bladder cancer.

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Background: Accurate prediction of short-term mortality in patients with acute pulmonary embolism (PE) is critical for optimizing treatment strategies and improving patient outcomes. The Pulmonary Embolism Severity Index (PESI) is the current reference score used for this purpose, but it has limitations regarding predictive accuracy. Our aim was to develop a new short-term mortality prediction model for PE patients based on deep learning (DL) with multimodal data, including imaging and clinical/demographic data.

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DERM12345: A Large, Multisource Dermatoscopic Skin Lesion Dataset with 40 Subclasses.

Sci Data

November 2024

Imperial College London, Division of Systems Medicine, Department of Metabolism, Digestion, and Reproduction, London, SW7 2AZ, United Kingdom.

Skin lesion datasets provide essential information for understanding various skin conditions and developing effective diagnostic tools. They aid the artificial intelligence-based early detection of skin cancer, facilitate treatment planning, and contribute to medical education and research. Published large datasets have partially coverage the subclassifications of the skin lesions.

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Background: Exercise is a key component of axial spondyloarthritis (axSpA) management. As telerehabilitation has become a viable solution for delivering remote care, the effectiveness of core stability exercises via this method remains under-researched.

Aim: To compare the effects of telerehabilitation-based synchronous versus asynchronous core stability exercises on core muscle endurance, spinal mobility, disease activity, physical function, and quality of life in patients with axSpA.

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Article Synopsis
  • Biotin is a water-soluble vitamin essential for carboxylation, and its deficiency (biotinidase deficiency, BD) can be classified as partial or profound depending on serum enzyme activity levels.
  • A study involving 302 patients in eastern Türkiye assessed various factors such as age, family history, and genetic mutations related to BD, with the majority diagnosed through neonatal screening.
  • The research identified 306 variants of the BTD gene, with the most common genetic mutations being c.410G>A (p.Arg137His) and c.1270G>C (p.Asp424His), and specific genotypes were linked to more severe deficiency symptoms.
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The journey of MEFV heterozygous children: with or without colchicine.

Eur J Pediatr

November 2024

Department of Pediatric Rheumatology, Faculty of Medicine, Istanbul University, İstanbul, Türkiye.

To investigate the rate of colchicine use in the longitudinal follow-up of familial Mediterranean fever (FMF) carriers and identify variables that could predict the necessity of colchicine treatment in this group. The study was conducted in 9 pediatric rheumatology centers. The files of children with MEFV gene carriers were retrospectively reviewed between February 2014 and May 2024.

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Heterozygous BTNL8 variants in individuals with multisystem inflammatory syndrome in children (MIS-C).

J Exp Med

December 2024

Section of Paediatric Infectious Disease, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK.

Multisystem inflammatory syndrome in children (MIS-C) is a rare condition following SARS-CoV-2 infection associated with intestinal manifestations. Genetic predisposition, including inborn errors of the OAS-RNAseL pathway, has been reported. We sequenced 154 MIS-C patients and utilized a novel statistical framework of gene burden analysis, "burdenMC," which identified an enrichment for rare predicted-deleterious variants in BTNL8 (OR = 4.

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Evaluation of uterocervical angle in intrauterine device displacement cases.

Arch Gynecol Obstet

December 2024

Department of Obstetrics and Gynecology, University of Health Sciences, Gaziosmanpasa Research and Training Hospital, Istanbul, Turkey.

Purpose: Intrauterine device is one of the most preferred birth control method in the world. Being able to predict that the intrauterine device will not dislocate is very important in terms of preventing unwanted pregnancies. Here, we evaluated the role of uterocervical angle in displacement of intrauterine device and to determine whether it has a discriminative role for displacement.

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The clinical policy of the Emergency Medicine Association of Türkiye (EMAT) provides guidance on the use of tranexamic acid (TXA) in emergency settings. TXA, an antifibrinolytic drug, is used to control bleeding by inhibiting plasminogen. Its applications have expanded from hemophilia and severe menstrual bleeding to include various forms of trauma and surgery-related bleeding.

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Article Synopsis
  • Time plays a critical role in diagnosing headache disorders and understanding their underlying mechanisms, highlighting the need for effective timing analysis in headache research.
  • A review of studies covering primary headache types—migraine, tension-type headache, and cluster headache—reveals distinct timing patterns, such as circadian rhythms in migraines and night-time occurrences in cluster headaches.
  • Understanding these time patterns can improve the phenotyping, management, and treatment of headache disorders, pointing towards new, personalized approaches in headache care.
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Flexible and navigable suction ureteral access sheath (FANS) is a potential game changer in flexible ureteroscopy (FURS). The influence of sheath size on outcomes needs research. The primary aim was to analyze 30-day single stage stone free status (SFS), zero fragment rate (ZFR) and complications when using 10/12Fr sheaths vis a vis other sheath sizes.

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Objective: In this study, we aimed to evaluate the relationship between the level of improvement in blood gas parameters in the first hours of age and normal and diffusion-restriction brain magnetic resonance imaging (MRI).

Materials And Methods: The study is a retrospective cohort study. Cases of the diagnosis of hypoxic-ischemic encephalopathy (HIE) who received therapeutic hypothermia in our unit between January 2022 and January 2024 were included in the study.

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Objectives Long-term consequences of COVID-19 in the post-pandemic era are still being investigated. Despite the growing data on COVID-19, there remains a lack of information regarding predictors of poor outcomes among chronic obstructive pulmonary disease (COPD) patients with COVID-19.  Methods A single-center prospective cohort study was conducted with a total of 172 adult COPD patients with COVID-19 pneumonia included.

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Xanthogranulomatous Cholecystitis: A Retrospective Review of Clinical Diagnosis and Treatment from a Single Center.

Healthcare (Basel)

November 2024

General Surgery Clinic, Haydarpasa Numune Research and Training Hospital, University of Health Sciences, Istanbul 34865, Turkey.

The objective of this study was to evaluate and compare the histopathological, clinical, and treatment characteristics of xanthogranulomatous cholecystitis (XGC) in patients undergoing cholecystectomy at a single center. : We aim to enhance the understanding of its presentation and improve its differential diagnosis from other gallbladder pathologies. : We retrospectively reviewed 6783 cholecystectomy cases performed between January 2015 and January 2023 at the General Surgery Clinic of Haydarpaşa Numune Training and Research Hospital, and a diagnosis of xanthogranulomatous cholecystitis was histopathologically established in 131 patients.

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Enhancing research methods: The role of systematic and scoping reviews in orthopaedics, sports medicine and rehabilitation.

J Exp Orthop

October 2024

Department of Orthopaedic Surgery and Traumatology Kantonsspital Baselland (Bruderholz, Liestal, Laufen) Bruderholz Switzerland.

Efforts to improve research standards in orthopaedics, sports medicine, physical therapy, and rehabilitation are ongoing. Rrehabilitation andomized Controlled Trials (RCTs) are widely regarded as the gold standard for the collection of primary data. Similarly, systematic reviews, due to their methodological rigor, have become the gold standard for evidence synthesis in medicine.

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Objective: Bipolar disorder (BD) is a recurrent chronic disorder characterised by fluctuations in mood and energy disposition. Diseases could lead to degenerative alterations in brain structures such as corpus callosum (CC). Studies demonstrated that abnormalities in CC are associated with BD symptoms.

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