228 results match your criteria: "Istanbul Kanuni Sultan Süleyman Education and Research Hospital[Affiliation]"

The aim of this study is to determine the mediating role of moral sensitivity in the effect of nurses' professional values on missed nursing care. A descriptive and correlational study was conducted with 640 nurses working in the inpatient units of a public and a private hospital with the MISSCARE Survey-Turkish, the Moral Sensitivity Questionnaire, and the Revised Nursing Professional Values Scale. Data analyses were performed using the Statistical Package for Social Sciences 26.

View Article and Find Full Text PDF

Background: This study aimed to determine the mediating role of social intelligence in the effect of nurses' work-related strain on trait anger and anger expressions. The challenging working conditions for nurses often result in increased strain and anger. Social intelligence could help to manage anger.

View Article and Find Full Text PDF

Objective: The objective of this study was to evaluate the efficacy and safety of isotonic and hypotonic intravenous fluids in maintenance fluid therapy for term infants.

Methods: This was a multi-centre, prospective, observational study conducted in 21 participating centres from December 30, 2020, to June 30, 2023. The study included term newborns requiring parenteral fluid therapy for maintenance (NCT04781361).

View Article and Find Full Text PDF

Introduction: The aim of the study was to analyse the clinical and demographic features of infants with gestational age (GA) of 32-37 weeks and birth weight (BW) of >1,500 g who developed treatment requiring retinopathy of prematurity (ROP).

Methods: Data on the infants with a GA of 32-37 weeks and BW >1,500 g who developed treatment requiring ROP (TR-ROP) were collected retrospectively from the 33 ROP centres in Turkiye. GA, BW, type of hospital, neonatal intensive care units (NICUs) level, presence of an ophthalmologist and neonatologist in the same hospital, length of stay in NICU, duration of oxygen therapy, comorbidities, type of ROP, and timing for TR-ROP development were analysed.

View Article and Find Full Text PDF
Article Synopsis
  • The study explores the use of epidural fat interposition (EFI) as an indirect indicator for diagnosing spondylolysis (SL) using lumbar MRI, highlighting its significance when analyzing T1-weighted images.
  • Out of 115 patients assessed, EFI was present in 85% of those with SL, showing a strong statistical difference compared to those with degenerative disc disease.
  • The findings suggest that EFI has high specificity and sensitivity, particularly at the lumbar 5 vertebra level, making it a reliable radiological sign for identifying spondylolysis in MRI scans.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to evaluate the prevalence of pancreatic steatosis (PS) using transabdominal ultrasonography in Turkish gastroenterology clinics and identify associated factors.
  • A total of 1,700 volunteers revealed a PS prevalence of 68.9%, with factors like age, BMI, and metabolic syndrome linked to its severity.
  • The study also found that 11.8% of PS cases were in lean individuals, who were generally younger and had lower metabolic risk factors compared to those with non-lean PS.
View Article and Find Full Text PDF

Anatomical Parameters of Percutaneous, Minimally Invasive, Direct Intralaminar Pars Screw Fixation of Spondylolysis.

World Neurosurg

August 2024

Department of Neurosurgery, Koc University School of Medicine, American Hospital, Neurosurgery Department, Istanbul, Turkey.

Objective: To investigate the anatomical parameters of the ideal screw trajectory for percutaneous intralaminar screw fixation of a pars defect in lumbar spondylolysis using computed tomography scans.

Methods: Using advanced radiological software, the ideal intralaminar screw trajectory was determined. The anatomical parameters of this trajectory were analyzed using a total of 80 single-level lumbar tomography scans in patients with spondylolysis at the lumbar 4 vertebrae and lumbar 5 vertebrae levels.

View Article and Find Full Text PDF

Background: The use of high-sensitivity troponin levels increases the sensitivity of the diagnosis of non-ST elevation myocardial infarction (NSTEMI). However, the inclusion of other factors in the differential diagnosis, apart from atherothrombosis causing myocardial injury, decreases the specificity of high-sensitivity troponin. In this study, we compared the efficacy of high-sensitivity troponin with serum oncostatin M in NSTEMI cases with elevated urea and creatinine.

View Article and Find Full Text PDF

Our aim in this study is to evaluate the cardiovascular findings of pediatric patients with primary Raynaud's phenomenon (RP) and to determine if there are any pathological findings. Our study included 42 pediatric patients aged between 7 and 18 who were diagnosed with primary RP and did not have any additional underlying structural vascular disease or secondary rheumatological conditions. The control group consisted of 30 healthy volunteers aged 7-18 years, matched by age and sex, without any additional diseases.

View Article and Find Full Text PDF
Article Synopsis
  • Non-obstructive azoospermia (NOA) is a prevalent and complex issue with varied treatment options and no definitive guidelines, leading to differing management practices internationally.
  • A comprehensive survey with 336 responses from specialists in 49 countries explored current medical and surgical strategies for NOA, analyzing results against existing guidelines and offering expert recommendations.
  • Key findings included diverse approaches to hormonal therapy, significant variation in sperm retrieval success rates, and differing protocols around varicocele repair and follicle-stimulating hormone cutoff levels for sperm retrieval.
View Article and Find Full Text PDF
Article Synopsis
  • * Conducted from July to September 2022, a questionnaire gathered responses from 367 doctors in 49 countries, focusing on how they diagnose NOA through methods like hormone tests and genetic analyses.
  • * The survey identified that while many practices align with guidelines, significant differences in approaches were found, underscoring the need for standardized, evidence-based international guidelines for NOA evaluation.
View Article and Find Full Text PDF
Article Synopsis
  • Triple negative breast cancer (TNBC) often recurs after treatment, particularly in those with residual disease post-chemotherapy, and capecitabine is commonly used as a follow-up treatment for these patients.! -
  • A study analyzed 170 TNBC patients who received capecitabine after neoadjuvant chemotherapy, finding a 30% recurrence rate and 18% death rate, with a 3-year disease-free survival (DFS) of 66% and overall survival (OS) of 74% in the cohort.! -
  • Results indicated that while capecitabine's effectiveness was lower than past studies, certain patients, especially those with specific residual disease characteristics, could still benefit from it,
View Article and Find Full Text PDF

Acute effect of transcranial direct current stimulation on photoparoxysmal response.

Epilepsy Res

March 2024

Departments of Neurology and Clinical Neurophysiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey; Department of Neurology, EMAR Medical Center, Istanbul, Turkey. Electronic address:

Introduction: Transcranial direct current stimulation (tDCS) is a non-invasive technique, used to modify the excitability of the central nervous system. The main mechanism of tDCS is to change the excitability by subthreshold modulation by affecting neuronal membrane potentials in the direction of depolarization or repolarization. tDCS was previously investigated as an alternative adjunctive therapy in patients with epilepsy.

View Article and Find Full Text PDF

Introduction: Migraine and epilepsy are two episodic disorders that share common pathophysiological mechanisms. The aim of our research was to assess the possible shared etiopathogenesis by analyzing the relations of headache, and seizure triggers, based on information obtained from a national cohort surveying the headache characteristics of 809 patients who had been diagnosed with idiopathic/genetic epilepsy.

Material And Methods: Our study utilized data from a multi-center, nationwide investigation of headaches in 809 patients with idiopathic/genetic epilepsy.

View Article and Find Full Text PDF
Article Synopsis
  • This systematic review and meta-analysis aimed to assess the prevalence of thirteen neurological issues in COVID-19 patients during and after the acute phase of the illness, with follow-ups at 3, 6, 9, and 12 months.
  • The study analyzed data from 126 eligible studies with over 1.5 million COVID-19 subjects, focusing on neurological symptoms like fatigue, cognitive impairment, and anosmia, among others.
  • Results showed that during the acute phase, the most common neurological symptoms were anosmia/hyposmia, fatigue, and headaches, with some symptoms like fatigue and cognitive impairment remaining significant even at the 3-month follow-up.
View Article and Find Full Text PDF

Other primary headache disorders: Data from the HEAD-MENA-A study in Africa, Asia, and the Middle East.

Clin Neurol Neurosurg

January 2024

Istanbul University, Istanbul Faculty of Medicine, Department of Neurology, Istanbul, Turkiye; EMAR Medical Center, Istanbul, Turkiye.

Objective: Other primary headache disorders (OPHD) are under-investigated compared to frequent primary headache types like migraine, tension-type headache, and trigeminal autonomic cephalalgias. Knowledge of the distribution and characteristics of OPHD subtypes is crucial for their recognition. We aimed to determine the prevalence at the hospital and headache clinics and clinical characteristics of OPHDs in patients from 13 countries.

View Article and Find Full Text PDF

Background: Children requiring kidney replacement therapy experience high burden of cardiovascular (CV) disease leading to increased mortality. Intima-media thickness (IMT) indicating atherosclerosis is a validated surrogate marker for future CV events.

Methods: We investigated the effect of different treatment modalities (dialysis, preemptive kidney transplantation (KTx), late KTx after dialysis) on IMT by multivariable linear mixed-effect modeling.

View Article and Find Full Text PDF

Background: The optimal treatment for metastatic colorectal cancer (mCRC) after the second line is still controversial. Regorafenib has been the standard of care in this setting as it improved overall survival (OS) compared to placebo. In real-world practice chemotherapy rechallenge is also a preferred option even though supporting evidence is not enough.

View Article and Find Full Text PDF

Background: Although acute headache following COVID-19 vaccination is widely acknowledged, the long-term progression of these headaches remains poorly understood. Our objective was to identify various phenotypes of prolonged or worsened headaches associated with COVID-19 vaccination and document any changes in these phenotypes over an extended period. Additionally, we aimed to document the diverse headache presentations among patients with pre-existing primary headaches.

View Article and Find Full Text PDF
Article Synopsis
  • - The paper discusses the need for a multidisciplinary approach involving family physicians, neurologists, and psychiatrists in managing complex neuropsychiatric cases like migraines, dementia, and mood disorders.
  • - It summarizes case-based discussions from the Mediterranean Neuropsychiatry Symposium, introducing the CARE framework to improve case reporting and evaluation in clinical settings.
  • - The findings emphasize that a biopsychosocial strategy is crucial for effective patient care, advocating for collaboration among healthcare providers to address diverse and intricate health needs.
View Article and Find Full Text PDF
Article Synopsis
  • The study investigates global practices and challenges in using sperm DNA fragmentation (SDF) assays, which can affect male reproductive potential, as outlined in the latest WHO manual.
  • A survey of 436 reproductive clinicians revealed that the most popular SDF assay is TUNEL, with a significant influence from availability on their choices.
  • Clinicians see the value of SDF testing in understanding infertility but face barriers like insufficient professional guidelines and a lack of accepted reference values for interpreting SDF results.
View Article and Find Full Text PDF

Background: Refugee populations have low levels of cancer awareness, low cancer screening rates, and a high rate of advanced or metastatic cancer at diagnosis. Educational interventions to improve cancer awareness and screening have been successful in other nationality refugee populations but have never been implemented in Afghan refugee populations. We aimed to estimate the level of breast cancer awareness among Afghan refugee women and test the feasibility of a telehealth breast cancer educational intervention to increase breast cancer awareness in this population.

View Article and Find Full Text PDF

Objective: The management of central venous catheter (CVC) occlusion remains an area without clear evidence-based guidelines. Studies have been conducted that compare the use of heparin and normal saline for reducing thrombosis, but the evidence is not strong enough to suggest a significant advantage of one over the other. Therefore, the study aimed to assess the effectiveness of heparin and normal saline flushing in preventing CVC occlusion in pediatric patients with cancer.

View Article and Find Full Text PDF

Objective: Optimal care in the delivery room is important to decrease neonatal morbidity and mortality. We aimed to evaluate neonatal resuscitation practices in Turkish centers.

Materials And Methods: A cross-sectional survey consisted of a 91-item questionnaire focused on delivery room practices in neonatal resuscitation and was sent to 50 Turkish centers.

View Article and Find Full Text PDF