8 results match your criteria: "Istanbul Health and Technology University School of Medicine[Affiliation]"
Autologous Ovarian Tissue Transplantation: Preoperative Assessment and Preparation of the Patient.
Obstet Gynecol Surv
November 2024
Prof. Doctor, Department of Obstetrics and Gynecology, Istanbul Koc University School of Medicine, Istanbul, Turkey.
Importance: Ovarian tissue cryopreservation (OTC) is an innovative and established fertility preservation method. More than 150 live births have been reported worldwide to date with the use of this strategy. OTC is one of the options to preserve fertility in prepubertal girls and for women who have time constraints and/or contraindications for ovarian stimulation for oocyte/embryo freezing before cancer treatment.
View Article and Find Full Text PDFTrends and Regional Differences for Fertility Preservation Procedures in Women With Breast Cancer.
Clin Breast Cancer
February 2025
Innovation Institute for Fertility Preservation, Yorkvillle, NY and New Heaven, CT; Department of Obstetrics and Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT. Electronic address:
Article Synopsis
- Breast cancer is the most common cancer in women of reproductive age, and chemotherapy often leads to the need for fertility preservation (FP), with established methods like embryo, oocyte, or ovarian tissue cryopreservation available.
- A study involving 1623 women from multiple countries showed a consistent increase in FP referrals, with 38.7% of referred women undergoing FP, particularly oocyte cryopreservation, which became more popular over the years.
- The findings highlight growing awareness and utilization of FP among young breast cancer patients, but they also point out significant regional differences that can inform policy decisions regarding FP care.
Oocyte cryopreservation with in vitro maturation for fertility preservation in girls at risk for ovarian insufficiency.
J Assist Reprod Genet
December 2023
Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, CT, 310 Cedar Street, FMB Room 224. New Haven, CT, USA.
Purpose: To assess the feasibility and outcomes of oocyte cryopreservation with in vitro maturation (IVM) in post-pubertal girls undergoing fertility preservation (FP) for primary ovarian insufficiency (POI) risk.
Methods: Ovarian stimulation was performed with an antagonist protocol or progesterone priming. Ultrasound monitoring was performed transabdominally.
Background: Better tools for post-chemotherapy amenorrhea risk assessment are needed for fertility preservation decision-making. Our aim was to determine the predictors of amenorrhea risk at 12 and 18 months post-chemotherapy in women with breast cancer.
Methods: 142 women with breast cancer were longitudinally followed for their menstrual changes at 6, 12, and 18 months after the completion of adjuvant chemotherapy with an Anthracycline-Cyclophosphamide-based (AC-based) or Cyclophosphamide-Methotrexate +5-Fluorouracil regimen.
Ovarian stimulation and oocyte cryopreservation in females with cancer.
Curr Opin Oncol
September 2023
Department of Obstetrics and Gynecology, Istanbul Health and Technology University School of Medicine, Istanbul, Turkey.
Purpose Of Review: We reviewed the most recent developments including the safety and effectiveness data and success rates in individualized ovarian stimulation protocols for adult and postpubertal females with cancer.
Recent Findings: In women with breast cancer, aromatase inhibitor- and tamoxifen-supplemented stimulation protocols increase the margin of safety by limiting estrogen exposure. The outcomes of ovarian stimulation appear similar between cancer and noncancer populations, even with the recently developed random-start protocols, which allow initiation of ovarian stimulation anytime during the menstrual cycle.
Outcomes of random-start letrozole protocol with PGT-A in women with breast cancer undergoing fertility preservation.
J Assist Reprod Genet
October 2023
Innovation Institute for Fertility Preservation, New Haven and NY, CT and NY, USA.
Unlabelled: PURPOSE : To compare the cycle characteristics and outcomes of random-start-controlled ovarian stimulation (RSCOS) protocols to the outcomes of standard-start-controlled ovarian stimulation (SSCOS) cycles and to report the utility of PGT-A in these cycles.
Methods: One hundred and seventeen who underwent SSCOS and 39 who underwent RSCOS for oocyte and/or embryo cryopreservation before breast cancer chemotherapy were retrospectively evaluated. Mean number of embryos and blastocyst euploidy rates were the main outcome measures.
We aimed to evaluate the levels of Spermidine, Syndecan 1, and Glypican 3 (GPC3) in the follicle fluid of women with diminished ovarian reserve (DOR) and to examine the relationship of these markers with the number of embryos and clinical pregnancy. A total of 27 women with DOR and 34 women with normal ovarian reserve who underwent in vitro fertilization procedure were included in this prospectively designed study. Spermidine, Syndecan 1, and GPC3 levels were studied in the follicle fluid samples taken from the women at the time of oocyte retrieval by ELISA method, and their relations with the cycle outcomes were examined.
View Article and Find Full Text PDFComparison of reference intervals derived by direct and indirect methods based on compatible datasets obtained in Turkey.
Clin Chim Acta
September 2021
Department of Statistics, Uludag University School of Medicine, Bursa, Turkey.
Background: Indirect derivation of reference intervals (RIs) from the laboratory information system (LIS) has been recently pursued. We aimed at evaluating the accuracy of indirectly predicted RIs compared to the RIs established directly from healthy subjects in the nationwide RI study in Turkey, targeting 25 major chemistry analytes.
Methods: LIS data were retrieved from the laboratory that performed measurements for the direct study.