Does vitamin C and vitamin E supplementation prolong the latency period before delivery following the preterm premature rupture of membranes? A randomized controlled study.

Objective: To determine whether maternal vitamin C and vitamin E supplementation after the premature rupture of membranes is associated with an increase in the latency period before delivery.

Methods: In the present prospective open randomized trial, 229 pregnant women with preterm premature rupture of membranes (PPROM) at ≥ 24.0 and < 34.

Diagnosis and management of cesarean scar pregnancy.

Objective: To evaluate the diagnosis and management modalities of cesarean scar pregnancy according to our experience.

Design And Setting: Retrospective study at the Women's Health Research and Education Hospital.

Patients: Six patients were diagnosed and treated for cesarean scar pregnancy (CSP) with dilatation and curettage, methotrexate (MTX), or laparatomy.

Prenatal diagnosis of 22q11.2 deletion syndrome in twin pregnancy: a case report.

Chromosome 22q11.2 deletion syndrome is a common genetic disorder, also known as DiGeorge syndrome. It occurs in approximately 1:4,000 births, and the incidence is increasing due to affected parents bearing their own affected children.

Osseous metaplasia of the cervix and endometrium: a case of secondary infertility.

Objective: To report a case of osseous metaplasia of the cervix and endometrium as a cause of secondary infertility.

Design: Case report.

Setting: Istanbul Bakirkoy Women and Children Teaching and Research Hospital.

Results of TOT operations alone and combined with other vaginal surgical procedures.

Objective: To evaluate the safety and efficacy of transobturator vaginal tape (TOT) procedure in women with stress urinary incontinence (SUI).

Methods: The study population consisted of 210 patients who were diagnosed as having stress urinary incontinence, and they underwent a TOT operation alone (99) or concomitant vaginal surgery (101) between January 2005 and February 2009 and were followed up for at least one year. Patients with detrusor overactivity and intrinsic sphincter deficiency were excluded.

HELLP syndrome: 8 years of experience from a tertiary referral center in western Turkey.

Objective: This study was performed to determine the incidence, symptomatology, complications, mode of delivery, treatment modalities, and risk factors for maternal outcome and perinatal outcome in women with HELLP syndrome.

Methods: A total of 303 pregnancies with hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome diagnosed antenatally were reviewed between 2002 and 2009. Demographic data, including age, parity, gestational age, and clinical and laboratory findings, were recorded from the medical files.

Using intraumbilical vein injection of oxytocin in routine practice with active management of the third stage of labor: a randomized controlled trial.

Objective: To estimate the efficacy of the routine use of intraumbilical vein injection of oxytocin with active management of the third stage of labor in reducing blood loss and length of the third stage.

Methods: In this prospective, randomized, double-blind trial, 412 women undergoing vaginal delivery who did not have risk factors for postpartum hemorrhage were randomly allocated to receive either 20 international units oxytocin diluted with 26 mL saline (n=207) or 30 mL saline (n=205) by intraumbilical vein injection. Active management of the third stage of labor (prophylactic injection of 10 international units oxytocin within 2 minutes of birth, early clamping of the umbilical cord, and controlled cord traction) was used in both groups.

Prenatal diagnosis of complete atrioventricular septal defect: perinatal and neonatal outcomes.

Objective. The purpose of this study was to establish the outlook for fetuses diagnosed with complete atrioventricular septal defect (cAVSD) prenatally and its relation to additional cardiac, extracardiac, and chromosomal abnormalities. Methods.

Membrane sweeping to induce labor in low-risk patients at term pregnancy: a randomised controlled trial.

Objective: To evaluate the efficacy of membrane sweeping at initiation of labor induction in low-risk patients at term pregnancy (38-40 gestational weeks).

Methods: This prospective study included 351 antenatal women who were randomly assigned to one of two groups: a sweeping of the membranes group (n = 181) and a no sweeping control group (n = 170). The primary outcome measure was the proportion of women who entered spontaneous labor within 1 week of entry into the study.

Is routine cervical dilatation necessary during elective caesarean section? A randomised controlled trial.

Objective: The purpose of this prospective randomised study was to determine the effect of routine cervical dilatation during elective caesarean section on maternal morbidity.

Methods: Participants with indication for elective caesarean section were randomly allocated to two groups. Group A (n = 200) women with intraoperative cervical dilatation; group B (n = 200) women with no intraoperative cervical dilatation.

Prenatal diagnosis of schizencephaly with 2D-3D sonography and MRI.

We report a case of schizencephaly diagnosed prenatally at 23 weeks of gestational age with two-dimensional (2D) and three-dimensional (3D) sonography and fetal brain MRI, confirmed by autopsy. The diagnostic method of choice is 2D transabdominal and transvaginal sonography, whereas additional 3D sonography and MRI may provide a better understanding of the pathology and related findings.

Experience with laparoscopic-assisted vaginal hysterectomy for the enlarged uterus.

Objective: The aim of this study is to evaluate the effect of uterine weight on the perioperative and postoperative outcomes of laparoscopically assisted vaginal hysterectomy (LAVH) for benign gynecological conditions.

Methods: In a retrospective observational study, 367 patients underwent LAVH (type I laparoscopic hysterectomy) for benign disorders at the Department of Gynecology at the Istanbul Bakirkoy Women and Children Hospital. Patients were divided into two groups with uterine weight <500 g and uterine weight > or =500 g.

When should we perform prophylactic antibiotics in elective cesarean cases?

Objective: The aim of this study was to determine whether the timing of prophylactic antibiotics at cesarean delivery influences maternal and neonatal infectious morbidity.

Study Design: This was a prospective, randomized trial. Four hundred patients that underwent elective cesarean section between June and December 2007 formed the study population.

Prenatal diagnosis of porencephaly secondary to maternal carbon monoxide poisoning.

Porencephaly is defined as an area of focal encephalomalacia that communicates with the ventricular system, giving the appearance of a dilated ventricle. It is assumed that vascular occlusion or an infectious process cause gray and white matter necrosis leading to cyst formation in the cerebral parenchyma. Possible etiology of porencephaly includes intracerebral thrombosis, intracranial hemorrhage and fetal infection.

Prenatal diagnosis and management of a ranula.

A ranula is a mucous extravasation cyst which appears as a swelling in the submental and submandibular regions. We describe a case of congenital ranula or retention salivary cyst diagnosed at 22 weeks' gestation. The fetal growth was normal, as was the amniotic fluid volume.

Fetal therapy in twin reversed arterial perfusion sequence pregnancies with alcohol ablation or bipolar cord coagulation.

Objective: We aimed to evaluate perinatal outcome of seven pregnancies with twin reserve arterial perfusion sequence.

Materials And Methods: The study group included seven cases of acardiac twins. Out of seven acardiac twins, two cases were in follow-up without any interventions.

First trimester diagnosis of sirenomelia: a case report and review of the literature.

Sirenomelia sequence is a rare lethal pattern of congenital anomalies characterized by a number of hallmark skeletal anomalies, including fusion of the lower extremities or a single lower limb, bilateral renal agenesis or dysgenesis with absent or hypoplastic renal arteries, oligohydramnios, and the presence of aberrant vasculature. The etiology is still controversial. Prognosis is very poor, with the babies being stillborn or succumbing soon after birth.

Perinatal and neonatal outcomes of growth restricted fetuses with positive end diastolic and absent or reversed umbilical artery doppler waveforms.

Objective: To evaluate the outcome of intrauterine growth restriction fetuses with absent or reversed end-diastolic flow in the umbilical artery.

Methods: This was a retrospective study conducted at the Department of Maternal Fetal Medicine of the Bakirkoy Women and Children's Teaching Hospital, Istanbul, Turkey between 2002 and 2006. Three hundred and ten pregnant women with growth-restricted fetuses confirmed by ultrasound were followed up with Doppler studies of the umbilical artery.

Prenatal ultrasonographic features of persistent urogenital sinus with hydrometrocolpos and ascites.

Objective: Hydrometrocolpos is a rare congenital disorder very rarely reported on prenatal sonography. In this study we report a persistent urogenital sinus with hydrometrocolpos and ascites at 24 weeks of gestation.

Case: Detailed ultrasonographic examination revealed female fetus with pelvic mass measured as 60 x 70 x 80 mm, anterior to sacral bone and inferior to bladder, and ascites, ureterocele, hydroureter, hydronephrosis but normal amniotic fluid.

Prenatal diagnosis of imperforate hymen with hydrometrocolpos.

Imperforate hymen is one of the most simple and most common anomalies in the female genital organs, occurring in 0.1% of girls born at term. Some are recognized because of mucocolpos at birth, but the diagnosis is usually not detected before puberty.

Prenatal diagnosis of an extralobar pulmonary sequestration.

Extralobar pulmonary sequestrations (ELS) are masses of non-functioning lung tissue that are supplied by an anomalous systemic artery and do not have a bronchial connection to the native tracheobronchial tree. On prenatal ultrasonography, an ELS appears as a well-defined echodense, homogeneous mass. Detection by color flow Doppler ultrasonography of a systemic artery from the aorta to the fetal lung lesion is a pathognomonic feature of fetal ELS.

Postmenopausal tuberculosis endometritis.

Tuberculosis remains a global health problem, primarily in developing countries with inadequate health services. A significant portion of tuberculosis in these settings is extrapulmonary, including tuberculosis of the genitourinary tract. Patients with genital tuberculosis are usually young women detected during work up for infertility.

The risk of malignancy index in discrimination of adnexal masses.

Objective: To assess the ability of the risk of malignancy index (RMI) based on a serum CA125 level, ultrasound findings and menopausal status, to discriminate benign from malignant adnexal masses.

Method: Between September 2002 and November 2004, 296 women with adnexal masses were enrolled. The sensitivity, specificity, positive (PPV) and negative predictive values (NPV) of the CA125 serum level, ultrasound findings and menopausal status in prediction of ovarian cancer were calculated and compared individually or combined into the RMI.

Monochorionic triamniotic triplet pregnancy with a co-triplet fetus discordant for congenital cystic adenomatoid malformation of the lung.

BACKGROUND: Spontaneous monochorionic triamniotic pregnancy is rare and is at increased risk for pregnancy complications. The presence of an anomalous fetus further complicates the management. CASE PRESENTATION: We present a case of monochorionic triamniotic triplet pregnancy diagnosed at 15 weeks of gestation with one fetus having developed a multicystic lung lesion, suggestive of congenital cystic adenomatoid malformation (CCAM).