Inflammopharmacology
November 2024
Department of Biostatistics, Marmara University School of Medicine, İstanbul, Türkiye.
Background: We aimed to examine the efficacy of intravenous vitamin C (IV-VC) in the treatment of hospitalized patients with moderate or severe COVID-19.
Method: We conducted a single-center and retrospective study including patients with COVID-19 diagnosis who were hospitalized. Patients were categorized into three groups as those who received low-dose (LDVC group, 2 g/day, n = 183) or high-dose IV-VC (HDVC group, 25 g/day, n = 41) and who did not receive IV-VC (control group, n = 46).
Florence Nightingale J Nurs
November 2024
Department of Nursing, İstanbul Rumeli University, Faculty of Health Sciences, İstanbul, Türkiye.
Aim: To determine the effect of kangaroo mother care (KMC) on perfusion index, heart rate, and oxygen saturation in premature infants who were discharged early and admitted to the neonatal intensive care unit (NICU) in the following days.
Methods: This study has a randomized controlled experimental design and uses a pretest-posttest control group model. This study included infants between December 2019 and December 2020 who were discharged early and subsequently admitted to the NICU.
Int J Gynaecol Obstet
November 2024
Department of Obstetrics and Gynecology, Biruni University School of Medicine, Istanbul, Turkey.
Spontaneous hemoperitoneum in pregnancy (SHIP) is defined as sudden, nontraumatic intraperitoneal bleeding that occurs during pregnancy or up to 42 days postpartum. The incidence ranges between 4 and 4.9 per 100 000 births.
View Article and Find Full Text PDFHemodial Int
January 2025
Ataturk University, Erzurum, Turkey.
Introduction: The study was performed to examine the effects of death anxiety on diet-fluid restriction non-adherence in hemodialysis patients.
Methods: This descriptive, cross-sectional, and correlational study was performed with 118 hemodialysis patients who received treatment in the dialysis unit of a university hospital and a state hospital in Elazığ, eastern Turkey. The study data were obtained with the "Descriptive Data Form", "Death Anxiety Scale", and "Dietary and Fluid Restriction Non-Adherence Scale".
Ther Adv Neurol Disord
November 2024
Department of Neuroscience, Central Clinical School, Monash University, 99 Commercial Road, Melbourne, VIC 3004, Australia.
Background: The relationship between coronavirus disease 2019 (COVID-19) infection and multiple sclerosis (MS) relapse and disease progression remains unclear. Previous studies are limited by small sample sizes and most lack a propensity-matched control cohort.
Objective: To evaluate the effect of COVID-19 infection on MS disease course with a large propensity-matched cohort.
Drug Discov Today
December 2024
Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address:
Autophagy, the lysosome-driven breakdown of intracellular components, is pivotal in regulating eukaryotic cellular processes and maintaining homeostasis, making it physiologically important even under normal conditions. Cellular mechanisms involving autophagy include the response to nutrient deprivation, intracellular quality control, early development, and cell differentiation. Despite its established health significance, the role of autophagy in cancer and other diseases remains complex and not fully understood.
View Article and Find Full Text PDFNat Prod Res
November 2024
Department of Pharmaceutical Botany, Faculty of Pharmacy, Ankara University, Ankara, Türkiye.
JCO Glob Oncol
October 2024
Department of Oncology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Purpose: Syrian refugees (SRs) have had difficulties in the diagnosis, treatment, and follow-up of chronic diseases, such as cancer, because of the conflict in the region. The cancer diagnosis and treatment process of SR are also a matter of curiosity. We aimed to compare the demographic characteristics and survival outcome data of SRs and Turkish citizens (TCs), and colorectal cancer (CRC) is one of the most common cancer types seen with similar frequency globally.
View Article and Find Full Text PDFArch Rheumatol
September 2024
Department of Internal Medicine, Fethi Sekin City Hospital, Elazığ, Türkiye.
Objectives: This study aimed to investigate the potential roles of proprotein convertase subtilisin/ kexin type 9 (PCSK9) and apelin in the etiology of fibromyalgia syndrome (FS).
Patients And Methods: The retrospective study was conducted between May 2022 and February 2023. Fifty-eight female FS patients (mean age: 45.
J Nephrol
November 2024
Division of Nephrology, Department of Internal Medicine, Koc University School of Medicine, Istanbul, Turkey.
Neurosurgery
January 2025
Department of Neurosurgery, University of Virginia, Charlottesville , Virginia , USA.
Background And Objective: This investigation evaluates the safety and efficacy of stereotactic radiosurgery (SRS) vs observation for Koos grade I vestibular schwannomas (VS).
Methods: In a multicenter study, we retrospectively analyzed data of patients with Koos grade I VS who underwent SRS (SRS group) or were observed (observation group). Propensity score matching was used to equilibrate demographics, tumor size, and audiometric data across groups.
BMC Infect Dis
November 2024
Department of Critical Care, Marmara University Pendik Training and Research Hospital, Pendik, Istanbul, Turkey.
Maxillofac Plast Reconstr Surg
November 2024
Faculty of Medicine, Department of Otorhinolaryngology, Marmara University, Pendik Training and Research Hospital, Fevzi Çakmak, Muhsin Yazıcıoğlu Street, Istanbul, 34899, Turkey.
Background: The aim of the study was to evaluate the etiology, incidence, demographics, and characteristics of maxillofacial fractures treated at a university hospital over a seven-year period.
Methods: We performed a retrospective analysis of 1,757 patients with maxillofacial fractures who were referred to our department between May 2012 and March 2019. The patients' demographic and clinical characteristics were noted, as well as the fracture type, location, and etiology.
Ulus Travma Acil Cerrahi Derg
November 2024
Department of Radiology, Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Istanbul-Türkiye.
Background: Acute appendicitis is one of the most common surgical emergencies. With antibiotic-first treatment strategies gaining importance, the risk of an appendiceal tumor as an incidental finding or as the cause of appendicitis presents an obstacle to a conservative approach. Neuroendocrine tumors, the most frequent type of appendiceal tumors, are difficult to diagnose preopera-tively due to their small size.
View Article and Find Full Text PDFOcul Immunol Inflamm
November 2024
Department of Ophthalmology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Purpose: To retrospectively analyze long-term outcomes of pediatric pars planitis (PP).
Methods: PP was defined as vitreal inflammation with snowbank or snowball formation in the absence of a related disease. Eighty-five eyes of 44 patients were included in this study.
J Eval Clin Pract
November 2024
Department of Nursing, Faculty of Health Science, İstanbul Topkapı University, İstanbul, Turkey.
Aim: The purpose is to develop a care package for the prevention of medical device-related pressure injuries using the Delphi Method.
Design: The study is a methodological.
Method: The care package was developed using the Delphi Method, a consensus-based technique.
S Afr J Surg
October 2024
Department of Paediatric Surgery, Mehmet Akif İnan Training and Research Hospital, Turkey.
Sci Rep
November 2024
Department of Surgery, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.
Mast cells are commonly found in pancreatic ductal adenocarcinoma (PDAC), yet their role in the disease remains uncertain. Although mast cells have been associated with depression in several diseases, their connection to PDAC in this context remains unclear. This study explored the correlation between mast cells and psychosocial stress in patients with PDAC.
View Article and Find Full Text PDFJ Clin Neurosci
December 2024
Medicana Hospital, Neurosurgery Clinic, Bursa, Turkey; Biruni University, Faculty of Medicine, Neurosurgery Department, İstanbul, Turkey. Electronic address:
Background: This study aimed to review the safety and prognosis of emergency lumbar microdiscectomy surgery during pregnancy.
Methods: The study included a cohort of ten consecutive pregnant patients who underwent urgent lumbar microdiscectomy surgery between 2016 and 2022-perioperative and perinatal clinical data derived from medical records-a retrospective analysis. The patients were evaluated based on age, gestational age, gravidity, parity, neurological examination findings, and visual analog scale (VAS) pain scores with the early and late postoperative results of mother and newborns with follow-up.
Am J Emerg Med
January 2025
University of Health Sciences, Haseki Training and Research Hospital, Department of Emergency Medicine, Istanbul, Türkiye. Electronic address:
Purpose: We investigated the efficacy and safety of a high-flow nasal cannula (HFNC) at different flow rates compared to noninvasive ventilation (NIV) in patients with acute chronic obstructive pulmonary disease (COPD) exacerbations.
Methods: This prospective, randomized, single-blind study assigned patients to one of three study groups. The NIV group (n = 47) received bilevel positive airway pressure.
Food Sci Nutr
October 2024
Department of Nutrition and Dietetics Sivas Cumhuriyet University, Faculty of Health Sciences Sivas Türkiye.
Herein, we aimed to investigate the physicochemical, bioactive, microbial, and sensory properties of 5 different ultraviolet (UV) treatment conditions, varying in flow rate (1.5-2.5-3.
View Article and Find Full Text PDFJACC Cardiovasc Interv
October 2024
Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Italy. Electronic address:
Anatol J Cardiol
October 2024
Department of Cardiology, Koşuyolu Heart Training and Research Hospital, İstanbul, Türkiye.
Background: To investigate the relationship between anxiety and white coat hypertension (WCH) using the hospital anxiety and depression scale-anxiety (HADS-A) score.
Methods: Participants lacking a pre-existing diagnosis of hypertension but displaying increased office blood pressure were included in this study. Subsequently, they were classified as either newly diagnosed sustained hypertension (SustHT) or white coat hypertension (WCH) patients, as determined by 24-hour ambulatory blood pressure monitoring measurements.
Pharm Dev Technol
December 2024
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Bezmialem Vakif University, Fatih, Istanbul, Turkey.
Polymeric micelles were prepared for the delivery of donepezil, a leading Alzheimer's disease drug, to enhance its transport across the blood-brain barrier (BBB). Poly(ethylene glycol)--poly(-butyl methacrylate) amphiphilic block copolymers were synthesized reversible addition-fragmentation chain transfer (RAFT) polymerization. The polymers were characterized by gel permeation chromatography and nuclear magnetic resonance spectroscopy.
View Article and Find Full Text PDFAudiol Neurootol
December 2024
Division of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Bezmialem Vakif University, Istanbul, Turkey.
Introduction: This study investigated the effect of different auditory stimuli and cognitive tasks on balance in healthy young adults.
Methods: Thirty-three participants, aged 23.33 ± 2.
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