319,532 results match your criteria: "Israel; Tel-Hai Academic College[Affiliation]"
Obes Rev
January 2025
AARDEX Group, Liège, Belgium; Department of Public Health, University of Liège, Liège, Belgium.
The increasing prevalence of obesity, complex nature of this chronic disease, and risks of developing obesity-related comorbidities outline the need for sustainable and effective management for people living with obesity. In addition to behavioral interventions, obesity medications (OMs) are increasingly considered an integral part of management of people living with obesity. OM adherence is essential to achieve the health benefits of these medications.
View Article and Find Full Text PDFExp Neurol
January 2025
Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, USA. Electronic address:
Hypoxic-ischemic (HI) brain injury is a common neurological problem in neonates. The postsynaptic density protein-95 (PSD-95) is an excitatory synaptic scaffolding protein that regulates synaptic function, and represents a potential therapeutic target to attenuate HI brain injury. Syn3 and d-Syn3 are novel high affinity cyclic peptides that bind the PDZ3 domain of PSD-95.
View Article and Find Full Text PDFClin Microbiol Infect
January 2025
Infectious Diseases Institute, Rambam Healthcare Campus; The Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology. Haifa, Israel.
Psychother Res
January 2025
Department of Psychology, University of Haifa, Haifa, Israel.
Objective.: There is a growing consensus that interpersonal processes are key to understanding psychotherapy. How might that be reflected in the brain? Recent research proposes that inter-brain synchrony is a crucial neural component of interpersonal interaction.
View Article and Find Full Text PDFEchocardiography
January 2025
Cardiology Department, Soroka University Medical Center, Beer-Sheba, Israel.
Background: Timing of treatment of aortic stenosis (AS) is of key importance. AS severity is currently determined by transthoracic echocardiography (TTE) with a main focus on mean trans-aortic gradients. However, echocardiography has its limitations.
View Article and Find Full Text PDFJMIR Med Educ
January 2025
Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Background: Patients in the United States have recently gained federally mandated, free, and ready electronic access to clinicians' computerized notes in their medical records ("open notes"). This change from longstanding practice can benefit patients in clinically important ways, but studies show some patients feel judged or stigmatized by words or phrases embedded in their records. Therefore, it is imperative that clinicians adopt documentation techniques that help both to empower patients and minimize potential harms.
View Article and Find Full Text PDFBrain Behav
January 2025
Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.
Introduction: Patients with bipolar disorder (BD) demonstrate episodic memory deficits, which may be hippocampal-dependent and may be attenuated in lithium responders. Induced pluripotent stem cell-derived CA3 pyramidal cell-like neurons show significant hyperexcitability in lithium-responsive BD patients, while lithium nonresponders show marked variance in hyperexcitability. We hypothesize that this variable excitability will impair episodic memory recall, as assessed by cued retrieval (pattern completion) within a computational model of the hippocampal CA3.
View Article and Find Full Text PDFOncologist
January 2025
Department of Medical Oncology, Princess Margaret Hospital, Toronto, ON M5G 2M9, Canada.
Background: Metastatic castration-resistant prostate cancer (mCRPC) has a poor prognosis, necessitating the investigation of novel treatments and targets. This study evaluated JNJ-70218902 (JNJ-902), a T-cell redirector targeting transmembrane protein with epidermal growth factor-like and 2 follistatin-like domains 2 (TMEFF2) and cluster of differentiation 3, in mCRPC.
Patients And Methods: Patients who had measurable/evaluable mCRPC after at least one novel androgen receptor-targeted therapy or chemotherapy were eligible.
EJNMMI Phys
January 2025
Department of Nuclear Medicine, Rambam Health Care Campus, P.O.B. 9602, 3109601, Haifa, Israel.
Background: A recently released digital solid-state positron emission tomography/x-ray CT (PET/CT) scanner with bismuth germanate (BGO) scintillators provides an artificial intelligence (AI) based system for automatic patient positioning. The efficacy of this digital-BGO system in patient placement at the isocenter and its impact on image quality and radiation exposure was evaluated.
Method: The digital-BGO PET/CT with AI-based auto-positioning was compared (χ, Mann-Whitney tests) to a solid-state lutetium-yttrium oxyorthosilicate (digital-LYSO) PET/CT with manual patient positioning (n = 432 and 343 studies each, respectively), with results split into groups before and after the date of a recalibration of the digital-BGO auto-positioning camera.
Strabismus
January 2025
Department of Ophthalmology, Shamir Medical Center, Zerifin, Israel.
: divergence insufficiency esotropia is a common cause for acquired esotropia and diplopia in adults. We present a novel procedure, superior plication of the lateral rectus using non-absorbable sutures, to address this condition and analyze the surgical outcomes. : This is a retrospective cohort analysis.
View Article and Find Full Text PDFCurr Opin Neurol
January 2025
Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Purpose Of Review: This scoping review summarizes key developments in the field of seizure forecasting.
Recent Findings: Developments have been made along several modalities of seizure forecasting, including long term intracranial and subcutaneous encephalogram, wearable physiologic monitoring, and seizure diaries. However, clinical translation of these tools is limited by various factors.
Brain Behav
January 2025
Technion Faculty of Medicine, Haifa, Israel.
Objective: Medical personnel show difficulty in differentiating psychogenic nonepileptic seizures (PNES) from epileptic seizures (ES). The purpose of this study was to conduct an initial feasibility assessment of the global dynamic impression (GDI) principle and to evaluate its effectiveness in enabling the diagnosis of epileptic versus psychogenic seizures using video footage of events, even by untrained personnel METHODS: We based this study on video footage showing five videos of PNES and five ES videos. We asked physicians and nurses from the emergency department, internal medicine department, neurology department, and medical students to classify the videos before and after learning the GDI principle.
View Article and Find Full Text PDFPest Manag Sci
January 2025
Department of Plant Pathology and Weed Research, Agricultural Research Organization, Volcani Institute, Rishon LeZion, Israel.
Agricultural landscapes adjacent to human settlements are subject to unique ecological dynamics that influence pest populations, yet the complexity of these relationships remains relatively underexplored. This review synthesizes current knowledge on the impacts of urban proximity on agricultural plant pathogen pest dynamics, focusing on spatial distribution patterns, theoretical frameworks from landscape ecology, and the specific mechanisms driving these interactions. The urban heat island effect, habitat fragmentation, and human activities contribute to altered microclimates, reduced natural predator populations, and increased pest proliferation near settlements.
View Article and Find Full Text PDFJ Thorac Dis
December 2024
College of Chemistry and Life Science, Beijing University of Technology, Beijing, China.
Background: Left ventricular assist device (LVAD) has been widely used as an alternative treatment for heart failure, however, aortic regurgitation is a common complication in patients with LVAD support. And the O-A angle (the angle between LVAD outflow graft and the aorta) is considered as a vital factor associated with the function of aortic valve. To date, the biomechanical effect of the O-A angle on the aortic valve remains largely unknown.
View Article and Find Full Text PDFHeliyon
January 2025
The Institute for Drug Research of the School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
RNA-targeting small molecules, particularly RIBOnuclease TArgeting Chimeras (RIBOTACs), represent a powerful and promising therapeutic approach by selectively degrading RNAs through ribonuclease (RNase) recruitment. Despite their potential, the development of effective RNase recruitment tools is still in its early stages and remains a critical area of research. Ribonuclease L (RNase L) is a key ribonuclease targeted by RIBOTACs, yet the tools available for studying RNase L are limited.
View Article and Find Full Text PDFToxicol Res (Camb)
February 2025
Department of Bioinformatics, Bharathidasan University, Tiruchirappalli, Tamil Nadu 620024, India.
Sugar substitutes are mostly artificial, man-made industrial products used as additives in food and beverages. Most of these substances flow through the digestive tract and food chains, becoming emerging organic contaminants in various abiotic and biotic environmental media. Here, we predict the mutagenicity and carcinogenicity of commonly used sugar substitutes using in silico based methods.
View Article and Find Full Text PDFThe consequences of climate change, accelerated by anthropogenic activities, have different effects on different ecosystems, and the severity of these effects is predicted to increase in the near future. The number of studies investigating how forest ecosystems respond to these changes is increasing. However, there remains a significant gap in research concerning how saproxylic organisms-one of the key contributors to the healthy functioning of these fragile ecosystems-will respond to the consequences of climate change.
View Article and Find Full Text PDFFront Bioeng Biotechnol
January 2025
Department of Biomedical Health Sciences, College of Public Health, East Tennessee State University, Johnson City, TN, United States.
is a foodborne pathogen commonly found in agricultural facilities; its prevalence, as well as increasing levels of disinfectant- and antibiotic-resistance, has significant costs for agriculture as well as human health. In an effort to identify potential new inhibitors of on abiotic surfaces, we developed a biomolecule screen of nutrient-type compounds because nutrients would have lower toxicity in animal facilities and bacterial nutrient utilization pathways might prove less susceptible to the development of bacterial resistance. After screening 285 nutrient-type compounds, we identified ten that significantly inhibited the ability of to colonize a plastic surface.
View Article and Find Full Text PDFNeurol Clin Pract
April 2025
Neurology, Vanderbilt University Medical Center, Nashville, TN.
Background: Huntington disease (HD) is a genetic neurodegenerative disorder. Given the focus on motor manifestations, nonmotor symptoms are frequently underappreciated in clinical evaluations, despite frequently contributing to primary functional impairment.
Recent Findings: A diagnosis of motor-onset as the definition of manifest symptoms misrepresents the complex nature of HD presentation.
Neurol Clin Pract
April 2025
Department of Health Care Policy, Harvard Medical School, Boston, MA.
Background And Objectives: Early presentation and acute treatment for patients presenting with ischemic stroke are associated with improved outcomes. The onset of the COVID-19 pandemic was associated with a large decrease in patients presenting with ischemic stroke, but it is unknown whether these changes persisted.
Methods: This study analyzed emergency department (ED) stroke presentations (n = 158,060) to all nonfederal hospitals in the 50 states and Washington, D.
Front Public Health
January 2025
Department of Psychological Sciences, Kent State University, Kent, OH, United States.
It is important to identify psychological correlates of vaccine hesitancy, including among people not from the United States (U.S.).
View Article and Find Full Text PDFFront Nutr
January 2025
School of Public Health, College of Health Science and Medicine, Wolaita Sodo University, Sodo, Ethiopia.
Background: Globally, more than 815 million estimated people worldwide suffer from malnutrition or are unable to access enough food due to malnutrition. Conflict remains the single most fundamental factor contributing to chronic malnutrition in the conflict-affected areas. Developing a healthy and balanced dietary pattern is essential for school children because their habits in this period may last longer.
View Article and Find Full Text PDFJ Crit Care Med (Targu Mures)
October 2024
Ariel University, School of Health Sciences, Ariel, Israel.
Background: We used a ten-item postoperative quality of recovery score (QoR-10) to assess the perioperative quality of care in an in-hospital ambulatory surgical unit.
Methods: In Phase 1 of this secular trend study (n=300 patients, 3-months duration), we collected QoR-10 scores and potential confounders, including type of anesthesia and surgery; co-morbidities; and anesthesia components of the Amsterdam scale-measured anxiety scores. Phase 2 was the one-month performance feedback learning phase in which modifiable variables identified in Phase 1 were translated to actionable steps, reinforcing the already existing routine of our department's clinical practices, including pain, shivering and anxiety.
JPEN J Parenter Enteral Nutr
January 2025
Department of Communication Disorders, Ariel University, Ariel, Israel.
Background: Chewing involves jaw movements that propel cerumen along the ear canal. This mechanism may be reduced in dysphagia, especially for older individuals who are enterally fed. Those patients may be at a higher risk for cerumen impaction and may require longer hospital stays.
View Article and Find Full Text PDFJ Child Lang
January 2025
Department of English Literature and Linguistics, Bar-Ilan University, Ramat Gan, Israel.
This study is one of the few research efforts investigating unexpected non-interactive foreign language acquisition in children with Autism Spectrum Disorder (ASD). Participants included 46 English-Hebrew-speaking children (ages 4;10 to 12;0): 14 autistic children who acquired English via non-interactive input (ASD-NI); 12 autistic children (ASD-Nat), and 20 non-autistic children with typical language development (TLD-Nat) who acquired English and Hebrew naturalistically. Morpho-syntactic abilities were assessed using Sentence Repetition tasks in both languages.
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