Smartphone use and personality: Their effects on sleep quality across groups using mediation analysis.

Purpose: The rapid rise in smartphone use has led to declining sleep quality. Excessive internet use has been linked to negative impacts on physical and mental health, and individual personality traits (PT) may contribute to internet addiction and mitigate its harmful effects. This study aims to: (1) examine whether PT mediate the relationship between smartphone use and sleep quality, and (2) investigate whether the relationship between smartphone use and sleep quality varies across different gender and age groups.

Moisture Sorption by Low-Cost Pyridinium-Based Protic Ionic Liquids: Kinetics and Physico-Electrochemical Properties.

We report the synthesis of two pyridinium-based room temperature protic ionic liquids (PILs), pyridinium bisulfate, [HPyr][HSO] and pyridinium sulphate, [HPyr][SO] and investigation of the kinetics of their water sorption behaviour and its influence on their density, ionic conductivity, and potential windows. The PILs were synthesized by the reaction of pyridine base with an acid, HSO, under solventless conditions, and confirmed by FTIR spectroscopy and 1H NMR spectra. The appearance vibration bands in the 3095-3252 cm range for -NH stretching in the FTIR spectra and a peak at a chemical shift of 8.

Isolation, characterization and pharmacological investigations of secondary metabolites from experimental and computational techniques.

Fungal metabolites are known for their broad therapeutic effects. In this context, the fungal strain of (FCBP-DNA-1266) was examined for its secondary metabolites and activities. This led to the isolation of naphtho-gamma-pyrone (aurasperone B) and a sterol (ergosterol), characterized using advanced spectroscopic techniques such as H NMR and C NMR.

Versatile platform of 3D/2D/1D:ZnFeO/NiAl-LDH/MWCNTs nanocomposite for photocatalytic purification of dinoseb and electrocatalytic O evolution reaction.

Integrating photocatalysis with electrocatalysis may represent a synergistic approach to address environmental and energy challenges. In this context, we explored synthesizing a series of nanocomposite materials using a solid-state approach involving simple grinding and subsequent thermal treatment for the photocatalytic purification of dinoseb and electrocatalytic oxygen evolution (OER). Interestingly, among the series of synthesized materials, 40 wt percentage of 3D/2D/1D:ZnFeO/NiAl-LDH/MWCNTs ternary nanocomposite (40-NZM) showed highly improved dinoseb detoxification and OER efficiencies compared to those of pure materials.

Harnessing bacterial metabolites for enhanced cancer chemotherapy: unveiling unique therapeutic potentials.

Cancer poses a serious threat to health globally, with millions diagnosed every year. According to Global Cancer Statistics 2024, about 20 million new cases were reported in 2022, and 9.7 million people worldwide died of this condition.

Unveiling the germination patterns of Alternaria porri (Ellis) by using regression analysis and hydrothermal time modeling.

Purple blotch disease is a major fungal disease of Allium cepa L. plants which is caused by the fungus Alternaria porri. The best conditions for the growth of Alternaria porri are temperatures between 22 °C and 25 °C and relatively high humidity.

A homozygous variant in ARHGAP39 is associated with lethal cerebellar vermis hypoplasia in a consanguineous Saudi family.

Cerebellar vermis hypoplasia refers to a varying degree of incomplete development of the cerebellum and vermis. A Saudi family with four affected individuals with cerebellar vermis hypoplasia, facial dysmorphology, visual impairment, skeletal, and cardiac abnormalities was ascertained in this study. Three out of four patients could not survive longer and had died in early infancy.

Assessment of natural radioactivity levels in rice samples and their implications for radiological protection.

This study investigates the levels of natural and artificial radioactivity in rice samples collected from various local markets in Islamabad, Pakistan. The Ra, Th, and K activity concentrations were measured through gamma-ray spectrometry with a NaI(Tl) detector. The average activity concentrations were 1.

Taxifolin: A flavonoid in the freezing medium augments post-thaw semen quality and in vivo fertility potential of buffalo bull spermatozoa.

This comprehensive study was carried out to investigate the effects of taxifolin in the freezing medium on post-thaw semen quality, and fertility potential of buffalo bull spermatozoa. Taxifolin was also evaluated for radical scavenging activity through DPPH (2, 2-diphenyl-1-picrylhydrazyl), and Nitric oxide (NO) inhibition (%) during in vitro conditions. Collected semen samples from four buffalo bulls were initially evaluated (consistency, volume, motility, and concentrations); the accepted samples were pooled, and diluted in extenders containing different doses of taxifolin (0 μM [control], 2 μM, 5 μM, 10 μM, and 20 μM).

An optimal estimation approach in non-response under simple random sampling utilizing dual auxiliary variable for finite distribution function.

Auxiliary data needs to be incorporated into survey sampling in order to create a precise population parameter estimator. This study investigates improving the efficiency of these estimators, the researchers use study variable [cumulative distribution function, (CDF)] and auxiliary variable (CDF, mean and ranks) to achieve this goal in the condition of non-response. The researchers suggest two ideal families of exponential estimators to obtain an enhanced population (CDF) estimators in simple random sampling under non-response, by utilizing the data from dual auxiliary variable.

evaluation of favipiravir-associated potential new drugs against polymerase enzyme of SARS-CoV-2.

Millions of lives have been lost to the deadly SARS-CoV-2 virus. Vaccines and antiviral drugs are essential scientific tools in combating viral infections. This study focused on the RdRp inhibitor favipiravir, exploring new analogs by substituting the fluorine atom on the pyrazine ring with both homocyclic and heterocyclic moieties.

Bioactivity of a dihydroxy flavone produced by EU0013 against the wilt pathogen of tomato.

Bioassay-guided isolation of a dihydroxy flavone from the cell extract of EU0013 was carried out using preparative LCMS and the structure was interpreted using 1D and 2D NMR spectra. The fungus was fermented in three different nutrient media Glucose Nutrient Broth, Glucose Peptone Yeast Broth, and Yeast Extract Broth and the cell extract was obtained using organics. Comparative LCMS profiles of the fungus confirmed the enhanced production of dihydroxy flavone in GPYB media.

Kinetics and thermodynamics investigations of efficient and eco-friendly removal of alizarin red S from water via acid-activated leaf powder and its magnetic iron oxide nanocomposite.

The present work aimed to highlight an efficient, readily accessible, and cost-effective adsorbent derived from (DS) leaf powder for removing the environmentally hazardous dye "alizarin red S" (ARS) from hydrous medium. A variant of the adsorbent is activated via sulfuric acid and composited with magnetic iron oxide nanoparticles (DSMNC). Both adsorbents are thoroughly characterized using techniques such as Fourier transform infrared spectroscopy, point of zero charge, energy-dispersive X-ray spectroscopy, and scanning electron microscopy, which show that they have a porous structure rich in active sites.

Assessment of fatty acid composition and amino acid profiles of three important fresh water fish species native to river Indus Pakistan.

This study was carried out to analyze the fatty acid and amino acid compositions of three economically important freshwater fish species, Mali (Wallago attu), Raho (Labeo rohita), and Mahseer (Tor putitora), indigenous to Indus River, Pakistan.. Amino acid profiling was done by high-performance liquid chromatography (HPLC) while gas chromatography (GC) was used for fatty acid analysis.

Excellent antibacterial and anti-inflammatory efficacy of amoxicillin by AgNPs and their conjugates synthesized using crude flavonoid extracts.

Unlabelled: Antibacterial resistance is considered to be one of the major causes for mortality in coming years. In recent years green nanotechnology played a key role in addressing this problem. Biocompatible metal nanoparticles have gained popularity owing to their excellent therapeutic effects and minimal side effects.

Risk assessment and soil heavy metal contamination near marble processing plants (MPPs) in district Malakand, Pakistan.

Soil heavy metals (HMs) pollution is a growing global concern, mainly in regions with rapid industrial growth. This study assessed the concentrations, potential sources, and health risks of HMs in agricultural soils near marble processing plants in Malakand, Pakistan. A total of 21 soil samples were analyzed for essential and toxic HMs via inductively coupled plasma‒optical emission spectrometry (ICP‒OES), and probabilistic health risks were evaluated via Monte Carlo simulation.

Integrating Laser-Induced Breakdown Spectroscopy and Ensemble Learning as Minimally Invasive Optical Screening for Diabetes.

Diabetes mellitus is a prevalent chronic disease necessitating timely identification for effective management. This paper introduces a reliable, straightforward, and efficient method for the minimally invasive identification of diabetes mellitus through nanosecond pulsed laser-induced breakdown spectroscopy (LIBS) by integrating a state-of-the-art machine learning approach. LIBS spectra were collected from urine samples of diabetic and healthy individuals.

Spider diversity in different habitats at District Mardan, Khyber Pakhtunkhwa Pakistan.

Spider species are important for maintaining ecological balance, controlling insect populations, and providing potential sources of medicinal compounds. Highlighting the importance of spider species, the present study was aimed at exploring the diversity of spider fauna and species richness in various habitats in District Mardan, Khyber Pakhtunkhwa, Pakistan, from March 2021 to December 2021. Spiders were collected through different methods: pitfall traps, cryptic searching, ground hand collection, aerial hand collection, and vegetation beating.

Phytosociology and ecological framework of forest tree species in the Toormang Valley, Dir Lower, Hindu Kush Range, Pakistan.

The phytosociological survey was conducted during 2018-2020. The research area was classified into five ecological zones based on habitat, physiognomy and species composition. Pc-Ord software was used for cluster analysis and four vegetation communities were established.

Eco-benevolent synthesis of ZnO-NPs and ZnO-MFs from Inula oculus-christi L. (Asteraceae) with effective antioxidant, antimicrobial, DNA cleavage, and decolorization efficiencies.

As a result of the changes occurring globally in recent years, millions of people are facing challenging and even life-threatening diseases such as cancer and the COVID-19 pandemic, among others. This phenomenon has spurred researchers towards developing and implementing innovative and environmentally friendly scientific methods, merging disciplines with significant technological potential, such as nanotechnology with medicinal plants. Therefore, the focus of this research is to synthesize zinc nanoparticles (ZnO-NPs) and microflowers (ZnO-MFs) using extracts of the medicinal plant I.