Neural reshaping: the plasticity of human brain and artificial intelligence in the learning process.

Unlabelled: This study explores the concept of neural reshaping and the mechanisms through which both human and artificial intelligence adapt and learn.

Objectives: To investigate the parallels and distinctions between human brain plasticity and artificial neural network plasticity, with a focus on their learning processes.

Methods: A comparative analysis was conducted using literature reviews and machine learning experiments, specifically employing a multi-layer perceptron neural network to examine regression and classification problems.

The effectiveness of implemented interventions at the workplace to promote the mental health of working women: A systematic review.

Over the last decades, a gradual increase in prevailing mental disorders in the adult population has been observed all over the world. Global estimates of anxiety, stress, depression, and mood disorders prevalence have also been high. Employed women are susceptible to experiencing some symptoms or mental disorders due to their lifestyle or working conditions.

Development and psychometric evaluation of the ethical conflict assessment instrument in nursing: A mixed-method protocol study.

Background: Ethical conflict among nurses has a significant impact on their health and the quality of nursing care. The lack of specific ethical and legal signs and obstacles for reporting ethical conflict in nurses has made diagnosis and the management of its negative consequences difficult. This study aims to develop a valid, reliable, evidence-based instrument to assess the ethical conflict of nurses in the sociocultural and managerial context of Iran.

Disaster health literacy for diabetics: A scoping review towards a framework.

Due to the increasing occurrence of natural disasters, it is essential to prioritize the improvement of health literacy during emergencies, particularly for individuals with chronic illnesses like diabetes who are especially vulnerable in the medical sector. The primary objective of this study was to identify the key themes within an emerging framework for disaster health literacy specifically tailored for diabetics. A scoping review design was selected based on the Arksey and O'Malley framework.

Investigating the relationship between happiness and self-esteem with self-efficacy in the clinical performance of midwives working in medical centers and comprehensive health services.

Background: Self-efficacy is one of the factors affecting correct performance, especially in emergency and stressful situations. The mental state of people can affect their performance. The present study was conducted with the aim of determining the relationship between self-esteem and happiness with self-efficacy in the clinical practice of midwives working in medical centers and comprehensive health services in Isfahan city.

Comparing the effects of smartphone-based and face-to-face education on the quality of life and coping skills among patients with multiple sclerosis: A randomized controlled trial.

Background: The plethora of troublesome signs and symptoms of multiple sclerosis (MS) reduces patients' quality of life (QOL) and coping skills. Face-to-face (F2F) education is effective and practical as it allows for more engagement and active learning. The use of mobile health technology to enhance health is now an excellent potential to establish a more efficient health system.

Comparison of the two treatment methods in primary hyperparathyroidism due to solitary parathyroid adenoma, Ultrasound-guided percutaneous alcohol ablation vs. parathyroidectomy: a randomized controlled trial.

Background: Primary hyperparathyroidism (pHPT) is the third most common endocrine system disorder. Parathyroidectomy (PTx) is the gold standard of care in symptomatic patients. Patients who are not surgical candidates may benefit from percutaneous ethanol ablation, which is a minimally invasive procedure.

The effect of anesthesia on postoperative cognitive dysfunction in adults undergoing cataract surgery: a systematic review.

Background: We systematically reviewed the evidence on the effect of anesthetic methods and drugs on the incidence of postoperative cognitive dysfunction (POCD) after cataract surgery.

Methods: The Web of Science, PubMed, and Scopus databases were searched for relevant English reports published from 2000 to August 2024. After full-text screening and checking the quality assessment of each article using the JBI checklist, 9 relevant articles were included in this study.

Relationship between sleep disorders and information processing speed in multiple sclerosis.

Objectives: It is estimated that up to 65 % of pwMS (people with multiple sclerosis) experience varying degrees of cognitive impairment, the most commonly affected domain being Information Processing Speed (IPS). As sleep disturbance is a predictor of detriments in IPS, the authors aimed to study the association between the severity of Restless Legs Syndrome (RLS) and Obstructive Sleep Apnea (OSA) symptoms with IPS in pwMS.

Methods: In a cross-sectional study, the authors enrolled people with relapsing-remitting and secondary progressive MS referred to the comprehensive MS center of Kashani Hospital in Isfahan, Iran.

Factors associated with dental care utilization among Iranian adult populations based on Anderson model.

Background: The utilization of dental care is affected by different factors. Despite the importance of dental care, there are significant disparities in its utilization among various population groups. The aim of this study was to identify the main factors of dental care utilization and the influences of the Health Transformation Plan (HTP) in Iran based on the Anderson model.

Association between nutritional status, daily nutrition delivery and clinical outcomes of critically ill adult patients admitted to the intensive care unit: a protocol for Isfahan multicentre prospective observational cohort ICU study (the Isfahan-ICU study).

Introduction: There is currently limited information regarding the association between the modified Nutrition Risk in Critically Ill (mNUTRIC) score, nutrition delivery and clinical outcomes in critically ill patients admitted to the intensive care unit (ICU) section.

Methods And Analysis: The Isfahan-ICU study is a multicentre, prospective observational cohort study that will be conducted on critically ill adults treated in the trauma or medical ICU sections of six hospitals to investigate whether clinical outcomes, including length of ICU stay and 30-day survival, vary by the mNUTRIC score at admission or the 7-day nutrition delivery. This paper outlines the Isfahan-ICU study protocol approved by the ethics committee of Isfahan University of Medical Sciences, Iran.

Efficacy and empathy of AI chatbots in answering frequently asked questions on oral oncology.

Objectives: Artificial intelligence chatbots have demonstrated feasibility and efficacy in improving health outcomes. In this study, responses from 5 different publicly available AI chatbots-Bing, GPT-3.5, GPT-4, Google Bard, and Claude-to frequently asked questions related to oral cancer were evaluated.

Balo concentric sclerosis, an emerging variant of multiple sclerosis: A case-series and literature review.

Introduction: Balo concentric sclerosis (BCS) is a rare demyelinating disease. This study aims to follow up on patients initially diagnosed with BCS and MS or presented with BCS in the context of MS.

Methods: This study was conducted at an MS clinic center in Isfahan, monitoring 2600 MS patients, among which 10 cases were related to BCS.

Antithrombotic therapy in adults with ectatic coronary artery disease: a systematic review and network meta-analysis.

Background: Many studies have validated the use of antiplatelet or anticoagulant therapy in coronary artery ectasia (CAE) to reduce major adverse cardiovascular events (MACE); however, it is not completely known which group of these antithrombotic medications is more effective. The purpose of this systematic review and network meta-analysis was to evaluate the efficacy of different anti-thrombotic treatments in adult patients with CAE.

Methods: This systematic review and meta-analysis followed preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines as well as PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses and adhered to a registered predetermined methodology noted in the prospective register of systematic reviews (PROSPERO) protocol.

Smart Mesoporous Silica Nanoparticles in Cancer: Diagnosis, Treatment, Immunogenicity, and Clinical Translation.

In cancer research and personalized medicine, mesoporous silica nanoparticles (MSNs) have emerged as a significant breakthrough in both cancer treatment and diagnosis. MSNs offer targeted drug delivery, enhancing therapeutic effectiveness while minimizing adverse effects on healthy cells. Due to their unique characteristics, MSNs provide targeted drug delivery, maximizing therapeutic effectiveness with minimal adverse effects on healthy cells.

Sertraline in depressed patients with or at risk for coronary heart disese: a systemic review.

Background And Aims: Depression is a prevalent comorbidity among patients with coronary heart disease (CHD). While recent studies have hinted at a possible association between CHD and antidepressant medications like sertraline, the existing evidence remains inconclusive. To investigate this potential link, we conducted a comprehensive systematic review.

Evaluation of efficacy and safety of generic tacrolimus (Suprotac®) compared to reference tacrolimus (Prograf) in kidney transplantation: a phase IV study.

Background: Transplant recipients are given an immunosuppressive regimen such as tacrolimus to prevent organ rejection. Suprotac® is a generic tacrolimus that is utilized in kidney transplantation regimen in Iran. This post-market study was conducted to evaluate the safety and efficacy of Suprotac® in comparison with Prograf®.

The Association Between Autism Spectrum Disorders and Dietary Intake of Carbohydrates in School-Aged Children in Iran: A Case-Control Study.

Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder with both genetic and environmental risk factors. Imbalanced dietary Intake has recently been proposed as a possible environmental risk factor for ASD. The purpose of this study was to investigate the possible connection between ASD and intake of various carbohydrate types.

Uncovering cerebral blood flow patterns corresponding to Amyloid-beta accumulations in patients across the Alzheimer's disease continuum using the arterial spin labeling.

Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder ranging from mild cognitive impairment (MCI) to AD dementia. Abnormal cerebral perfusion alterations, influenced by amyloid-beta (Aβ) accumulations, have been implicated in cognitive decline along this spectrum.

Objective: This study investigates the relationship between cerebrospinal fluid (CSF) Aβ1-42 levels and regional cerebral blood flow (CBF) changes across the AD continuum using the Arterial Spin Labeling (ASL) technique.

Systematic Review of Patient Preference Studies in Non-metastatic Breast Cancer Adjuvant Medication Therapy: Attribute Selection.

Context: Breast cancer poses significant challenges due to its high incidence and prevalence, necessitating heightened attention. Understanding how patients prioritize different treatment options based on various attributes can assist healthcare decision-makers in maximizing patient utility. The discrete choice experiment, a conjoint method, facilitates preference elicitation by presenting different attributes and choices.

Mechanisms of apoptosis-related non-coding RNAs in ovarian cancer: a narrative review.

Ovarian cancer remains a major challenge in oncology due to its complex biology and late-stage diagnosis. Recent advances in molecular biology have highlighted the crucial role of non-coding RNAs (ncRNAs) in regulating apoptosis and cancer progression. NcRNAs, including microRNAs, long non-coding RNAs, and circular RNAs, have emerged as significant players in the molecular networks governing ovarian cancer.

Recent advances in improved efficacies of gold nano-formulations in treatment of skin cancer: a systematic review.

Skin cancer is the commonest malignancy for the population. Conventional skin cancer treatments include chemotherapy and surgery, but a large number of the chemotherapeutic drugs applied currently have undesirable possessions. The aim of this study is to provide a complete and acute assessment of the antitumor capability of gold nano-formulations in skin cancer as a new and more effectual delivery system for targeted therapy.

Differential effects of β-hydroxybutyrate and α-ketoglutarate on HCT-116 colorectal cancer cell viability under normoxic and hypoxic low-glucose conditions: exploring the role of SRC, HIF1α, ACAT1, and SIRT2 genes.

Recent therapeutic strategies have highlighted the potential of β-hydroxybutyrate (BHB) and α-ketoglutarate (α-KG) as effective anticancer agents, particularly for colon cancer. These metabolites can modulate cellular metabolism and induce epigenetic changes, inhibiting tumor growth. Nonetheless, certain cancer cells may utilize ketone bodies, like BHB as nutrient sources under hypoxic conditions, potentially reducing treatment efficacy.

Prevalence of food allergy and its association with atopic dermatitis in Iran: Results from the PERSIAN birth cohort.

Background: The incidence of food allergy (FA) has been increasing worldwide, causing growing concern on a global scale.

Objective: This birth cohort study analyzes the incidence of reported FA and other atopic comorbidities in children from birth to age 2 years who were living in 4 urban and semiurban areas in Iran.

Methods: Children were followed from birth until age 24 months, with follow-up questionnaires administered through parent or guardian interviews conducted when the children were aged 2, 4, 6, 12, and 24 months.