Prevalence of traditional atherosclerotic risk factors in newly diagnosed colorectal and breast cancer patients.

Due to the shared risk factors between cardiovascular disease (CVD) and certain cancers such as breast cancer (BC) and colorectal cancer (CRC), our study aimed to assess the CVD risk factors among newly diagnosed patients with BC and CRC. The study utilized baseline data from the ongoing Cardiovascular Events in Breast and Colorectal Cancers (CIBC) cohort study conducted in Isfahan since 2019. Only patients who had recently been diagnosed with BC or CRC and had not undergone any treatment were included in the study.

Evaluating the impact of bioenergy economy-based health improvement (BEHI) as a mind-body intervention on laboratory, clinical and psychological factors in post-MI patients: A randomized controlled trial.

Background: Patients with ischemic heart disease often exhibit various psychological factors that increase the risk of future cardiovascular events. Therefore, in addition to rehabilitation programs, there is a need for more interventional psychotherapy. Bioenergy Economy-based Health Improvement (BEHI) is a mind-body intervention that may address these issues.

Temporal trend of short-term mortality in acute myocardial between 2000-2017: A multi-centric Iranian registry.

Background: The study explores the enduring challenges of cardiovascular disease mortality, emphasizing myocardial infarction rates as a proxy for cardiovascular disease in Iran. It analyzes the 28-day mortality trends after Acute Myocardial Infarction (AMI) from 2000 to 2017.

Methods: This retrospective cohort study is based on data from a multi-centric hospital-based registry in Isfahan.

Age at menarche and risk of premature coronary artery disease: results from Iran premature coronary disease (IPAD) study.

Background: Premature coronary artery diseases (PCAD) is a major health concern. Finding the potential risk factors for this health issue is crucial for early detection and prevention. This study aimed to evaluate the relation between age at menarche and PCAD presence and severity.

Dietary patterns and premature coronary artery disease: result from the Iran premature coronary artery disease (IPAD) study.

Background: Premature coronary artery disease (PCAD) is one of the major health concerns leading to considerable death and disabilities. This study aimed to evaluate the relationship of dietary patterns with risk of PCAD.

Methods: Iran premature coronary diseases (IPAD) is a case-control study consists of 3159 participants.

Alterations in serum levels of calcium, vitamin D, phosphorus, and parathyroid hormone in patients with clinically confirmed familial hypercholesterolemia: a cross-sectional study.

Background: Familial hypercholesterolemia (FH), an autosomal dominant disease, is associated with an increased risk of premature cardiovascular disease (CVD). This study aimed to examine the variations in serum levels of calcium, vitamin D, phosphorus, and parathyroid hormone (PTH) among FH patients, as these factors have been associated with an increased susceptibility to CVD.

Materials And Methods: In this cross-sectional study, the authors used data from Isfahan FH registry.

Highlighting roles of autophagy in human diseases: a perspective from single-cell RNA sequencing analyses.

Autophagy, the lysosome-driven breakdown of intracellular components, is pivotal in regulating eukaryotic cellular processes and maintaining homeostasis, making it physiologically important even under normal conditions. Cellular mechanisms involving autophagy include the response to nutrient deprivation, intracellular quality control, early development, and cell differentiation. Despite its established health significance, the role of autophagy in cancer and other diseases remains complex and not fully understood.

The Effect of Vitamin D Deficiency Treatment on Lipid Profile and C-reactive Protein in Patients with Ischemic Heart Disease: Double-blind Randomized Clinical Trial.

Background: Atherosclerosis is the main process in coronary artery stenosis, which is exacerbated by vitamin D deficiency. This study aims to investigate the relationship between vitamin D deficiency treatment, lipid profile, and C-reactive protein (CRP) in ischemic heart disease (IHD).

Materials And Methods: This is a double-blind, randomized clinical trial involving 44 IHD patients with hypovitaminosis, aged 40-65 years, who were referred to Chamran Specialty Heart Hospital, Isfahan, Iran.

Clinical, laboratory, and procedural predictors of slow flow/no reflow phenomenon after emergency percutaneous coronary interventions in ST-elevated myocardial infarction.

Background: Emergency percutaneous coronary intervention (PCI) is a common treatment for ST-elevated myocardial infarction (STEMI) patients. However, the coronary slow flow/no reflow phenomenon (CSF/NRP) can occur as a complication during or after the procedure. Identifying predictors of CSF/NRP after emergency PCI in STEMI patients can help clinicians anticipate and prevent this complication.

Improvement of Care Cascade for Hypertension and Diabetes in Rural China: Protocol for an Implementation Study.

The management of hypertension and diabetes poses significant challenges to China's healthcare system, necessitating seamless patient progression through screening, diagnosis, management, and control. Utilizing the care cascade model, this study aims to systematically identify patient drop-offs and devise strategies to address healthcare delivery bottlenecks for hypertension and diabetes in rural China. This study consists of three phases.

Preliminary Results of Iran Premature Coronary Artery Disease (IPAD study) and Implementation of IPAD Biobank: A Case-Control Study.

Background: Iran Premature Coronary Artery Disease (IPAD) is one of the first and largest studies of its kind in Asia that investigates different aspects of premature coronary artery disease (PCAD) in different ethnic groups in multiple cities. In this paper, we aim to describe the IPAD biobank establishment and present some preliminary results of the IPAD study.

Methods: This case-control study was conducted on patients with documented angiography from different ethnicities in more than ten cities of Iran (males aged 60 years and below and females aged 70 years and below).

Prognostic Role of Ultrasound Diagnostic Methods in Patients with Acute Decompensated Heart Failure.

Objectives: To evaluate the prognostic value (total mortality + repeated hospitalization for heart failure (HF)) of ultrasound diagnostic methods in patients with acute decompensated HF (ADHF).

Methods: The subjects were patients with chronic HF, who were hospitalized for ADHF. Using ultrasound methods-lung ultrasound, ultrasound assessment of hepatic venous congestion as per the venous excess ultrasound (VExUS) protocol, and indirect elastometry-we assessed the number of B-lines, hepatic venous congestion, and liver density of the patients.

Accuracy of novel anthropometric indices for assessing the risk for progression of prediabetes to diabetes; 13 years of results from Isfahan Cohort Study.

Objective: We examined the accuracy of novel anthropometric indices in predicting the progression of prediabetes to diabetes.

Subjects And Methods: This study was performed on the pre-diabetic sub-population from Isfahan Cohort Study (ICS). Participants were followed up from 2001 to 2013.

Association of obesity status and the risk of long-COVID: Isfahan COVID cohort study.

People with COVID-19 infection continue to have their symptoms or develop new ones after recovery. This is called long-COVID syndrome. We aimed to examine the association of general and abdominal obesity with long COVID.

Gender differences in cardiac rehabilitation participation and outcomes: an 18-year retrospective study in Iran.

Background: Cardiac rehabilitation (CR) is crucial for addressing cardiovascular diseases globally, with a specific emphasis on gender differences. Despite its demonstrated benefits for women, there's limited acceptance globally, especially in low- and middle-income countries. The program aims to optimize risk factors and improve overall patient well-being.

Assessing the built environment through photographs and its association with obesity in 21 countries: the PURE Study.

Background: The built environment can influence human health, but the available evidence is modest and almost entirely from urban communities in high-income countries. Here we aimed to analyse built environment characteristics and their associations with obesity in urban and rural communities in 21 countries at different development levels participating in the Prospective Urban and Rural Epidemiology (PURE) Study.

Methods: Photographs were acquired with a standardised approach.

Clinical and laboratory manifestations, ECG findings, and outcomes of right atrial myxoma: a systematic review of cases reported worldwide.

Background: The presence of cardiac myxoma in the right atrium (RA) is rare. There is limited knowledge regarding the clinical symptoms and diagnosis of RA myxoma. This systematic review aimed to provide a summary of the clinical and laboratory characteristics, electrocardiogram (ECG) findings, and outcome previous cases with RA myxoma.

Endocan as a biomarker for acute respiratory distress syndrome: A systematic review and meta-analysis.

Background And Aims: Endocan is a marker of endothelial damage. Data regarding the association of this proteoglycan and acute respiratory distress syndrome (ARDS) is discrepant. Hence, this study sought to investigate the possible correlation between serum/plasma endocan concentration and ARDS.

Efficacy of prescribing Inderal for polymorphic ventricular tachycardia in a young patient with the normal QT interval: A case report study.

Polymorphic ventricular tachycardia (PVT) is a group of life-threatening heart rhythm disorders. These arrhythmias share similar electrocardiographic characteristics but require different modes of therapy for effective treatment. It is important to note that the medications that are considered the first-line treatment for one type of PVT may not be appropriate for another type, and may worsen the condition.