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A systematic review and meta-analysis of the association between the apolipoprotein E genotype and delirium.
Psychiatr Genet
April 2016
aSligo Mental Health Services bPathology Department, Sligo Regional Hospital, Sligo cCognitive Impairment Research Group (CIRG), Graduate-Entry Medical School University of Limerick, Limerick dSligo Medical Academy, NUI Galway, Galway, Ireland eResearch and Academic Institute of Athens, Athens, Greece.
The role of apolipoprotein E (APOE) in Alzheimer's disease and other dementias has been investigated intensively. However, the relationship between APOE and delirium has only recently been explored in studies that have included relatively small samples. A meta-analysis of the published pooled data is timely to explore the relationship between APOE and delirium and to inform further research in this topic.
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