1 results match your criteria: "Iran. Email: mh.nasresfahani@ royaninstitute.org.[Affiliation]"
Effects of Streptozotocin Induced Diabetes on One-Carbon Cycle and Sperm Function.
Cell J
January 2024
Department of Animal Biotechnology, Reproductive Biomedicine Research Center, Royan Institute for Biotechnology, Isfahan, Iran. Email: mh.nasresfahani@ royaninstitute.org.
Objective: Diabetic men suffer an increased risk of infertility associated with signs of oxidative damage and decreased methylation in sperm pointing to a deficit of the one-carbon cycle (1CC). We aimed to investigate this deficit using mice models (type 1 and 2) of streptozotocin-induced diabetes.
Materials And Methods: In this experimental study, 50 male mice, aged eight weeks, were divided randomly into four groups: sham, control, type 1 diabetes mellitus (DM1), and DM2.