The role of artificial intelligence in preoperative planning for Total Hip Arthroplasty: a systematic review.

Background: Total Hip Arthroplasty (THA) is a transformative surgical intervention for hip joint disorders, necessitating meticulous preoperative planning for optimal outcomes. With the emergence of Artificial Intelligence (AI), preoperative planning paradigms have evolved, leveraging AI algorithms for enhanced decision support and imaging analysis. This systematic review aims to comprehensively evaluate the role of AI in THA preoperative planning, synthesizing evidence from studies exploring various AI techniques and their applications.

Efficacy of intermittent fasting on improving liver function in individuals with metabolic disorders: a systematic review and meta-analysis.

Background: Intermittent fasting (IF) can be an effective dietary therapy for weight loss and improving cardiometabolic health. However, there is scant evidence regarding the role of IF on indicators of liver function, particularly in adults with metabolic disorders. Therefore, we performed a systematic review and meta-analysis to investigate the effects of IF on liver function in adults with metabolic disorders.

The impact of Covid-19 on harm reduction policies in Iran: an interrupted time series analysis.

Background: The global emergence of the Covid-19 pandemic in 2019 posed unprecedented challenges to healthcare systems, disrupting routine services and necessitating swift adaptations. Harm reduction programs, vital for addressing substance use-related health risks, faced unique challenges during the pandemic, impacting vulnerable populations. This study focuses on the repercussions of Covid-19 on harm reduction policies in Iran, specifically examining the distribution of condoms, syringes, and methadone to high-risk individuals attending Triangle Centers.

Comparison of Empathy with Patients between Surgical and Psychiatric Medical Residents.

Background: Empathy is considered paramount to the medical profession because it affects patients' satisfaction, compliance, and quality of care. It has been studied that medical residents in non-psychiatry specialties (especially general surgery) pay less attention to their patients' experiences and emotions. This study measured and compared surgical and psychiatric medical residents' empathy scores.

Barriers and Facilitators of Research Finding Utilization in Healthcare: A Scoping Review.

Background: We aimed to identify and classify barriers and facilitators of implementation of research finding in healthcare.

Methods: A scoping review was conducted using Preferred Reporting Items for Systematic Reviews and Meta-analyses Extension for Scoping Reviews (PRISMA-ScR). Articles were extracted from online databases.

Coal Worker's Pneumoconiosis Mimicking Lung Cancer in a 75-Year-Old Woman With a History of Breast Cancer: A Clinical Case Report.

Pneumoconiosis, caused by inhaling mineral dust, remains a significant occupational disease, despite a declining incidence. Coal workers' pneumoconiosis (CWP), a common subtype, varies in presentation from simple to complicated forms. Differential diagnosis is crucial, especially when CWP manifests as lung masses mimicking malignancy.

Assessing equity in the distribution of hospital beds in Lorestan, western Iran: a regional analysis.

Background: Equity in health service delivery ensures that resources are distributed based on need, minimizing barriers to access and reducing health disparities. Hospital beds are a critical healthcare resource, essential for providing timely and effective medical care. This study aims to evaluate the equity in the distribution of hospital beds in Lorestan Province, western Iran, using the Gini coefficient and Lorenz curve as analytical tools.

Barriers and challenges of establishing family physician policy for urban population; evidence from a qualitative study in Iran.

Background: Family physicians play a crucial role in healthcare delivery systems worldwide. In Iran, the family physician program has been introduced in only two provinces, with its expansion to other regions currently stalled due to various challenges. This study aims to identify the barriers and challenges hindering the effective implementation of the family physician program in urban areas of Iran.

Comparison of the effect of Sacubitril/Valsartan with Losartan and Captopril in improving right ventricular function in patients with right heart failure, a randomized clinical controlled trial.

Background: There is evidence supporting the efficacy of Sacubitril /Valsartan for improving left heart failure, but few studies have examined its effects on right ventricular (RV) dysfunction. The current study aimed to investigate the effects of Sacubitril /Valsartan on RV dysfunction in patients with right heart failure.

Methods: The current study was a randomized and parallel clinical trial study.

Assessment of Coffee Consumption on Post-Cesarean Section Bowel Movements.

Objectives: Gastrointestinal complications and bowel movement disorders are common complications of abdominal surgery. Considering the effects of coffee and the high prevalence of cesarean section operations, this study aimed to assess how coffee consumption affected the motility of the intestines.

Methods: This was a triple-blind clinical trial study performed on 200 cases of randomly chosen women who had undergone cesarean section in both Akbarabadi and Firouzgar hospitals, and they were randomly divided into two groups.

The interactions of spontaneous abortion, dietary intake of selenium, and fat mass and obesity associated (FTO) genotype: a case-control study in Iran.

Background: Spontaneous abortion (SA) is reported to be associated with Fat Mass And Obesity-Associated FTO genotype and dietary intake of selenium. This research assessed the potential interactions between the risk of SA, dietary selenium intake, and the FTO rs9939609 polymorphism.

Methods: This case-control study encompassed 192 women who experienced SA and 347 control participants.

The impact of the Covid-19 pandemic on outpatient visits for patients with cancer in Iran: an interrupted time series analysis.

Background: The Covid-19 pandemic has posed unprecedented challenges to healthcare systems worldwide, affecting routine medical services, including for cancer patients. This study investigates the impact of the Covid-19 pandemic on outpatient visits for patients with cancer in Iran.

Methods: We conducted an interrupted time series analysis (ITSA) on data collected from electronic medical records.

A1, an innovative fluorinated CXCR4 inhibitor, redefines the therapeutic landscape in colorectal cancer.

Background: Colorectal cancer (CRC) is a globally prevalent malignancy, primarily affecting the colon and rectum, characterized by uncontrolled cellular changes in the intestinal wall lining. Recent evidence underlines the significant role of the CXCL12/CXCR4 axis in the development of CRC, suggesting that inhibiting this pathway could be a promising therapeutic approach. This study focuses on investigating the potential of N, N''-thiocarbonylbis (N'-(3,4-dimethyl phenyl)-2,2,2-trifluoroacetimidamide) (A1), a novel fluorinated CXCR4 inhibitor, through a comprehensive analysis encompassing in silico, in vitro, and in vivo studies.

Urodynamic Changes Following Fewer Injection Sites of Intravesical Botulinum Toxin in Idiopathic Detrusor Overactivity: A Double-Blinded Prospective Randomized Clinical Trial.

Introduction And Hypothesis: This study was aimed at evaluating the therapeutic effects of a modified intravesical botulinum toxin injection technique (fewer injection sites under local anesthesia), in comparison with the conventional technique for patients with idiopathic detrusor overactivity, considering the urodynamic parameters.

Methods: In this double-blinded randomized clinical trial, 78 adult females with idiopathic detrusor overactivity were divided into two groups: conventional and modified groups. In the conventional method, patients received intradetrusor botulinum toxin injection at 20 sites under general or spinal anesthesia in a trigone-sparing fashion.

Short-Term Assessment of High-Sensitivity C-Reactive Protein (hs-CRP) Changes Following One Anastomosis Gastric Bypass (OAGB) in Patients with Obesity: A Prospective Cohort Study.

Background: Obesity, characterized by excessive adipose tissue, is associated with chronic low-grade inflammation and elevated inflammatory markers such as high-sensitivity C-reactive protein (hs-CRP). This inflammation is linked to obesity-associated medical problems, including cardiovascular diseases. One anastomosis gastric bypass (OAGB) has emerged as an effective metabolic and bariatric surgical procedure to address severe obesity and its associated inflammatory state.

Clinical presentation and management challenges of sphingosine-1-phosphate lyase insufficiency syndrome associated with an SGPL1 variant: a case report.

Background: This case report describes a unique presentation of sphingosine-1-phosphate lyase insufficiency syndrome (SPLIS) caused by a rare SGPL1 variant, highlighting the diagnostic and management challenges associated with this condition.

Case Presentation: A 2-year-old Iranian female presented with steroid-resistant nephrotic syndrome (NS), primary adrenal insufficiency (AI), growth delay, seizures, and hyperpigmentation. Laboratory evaluation revealed hypoalbuminemia, significant proteinuria, hyperkalemia, and elevated adrenocorticotropic hormone (ACTH) levels.

Cinnamic acid conjugated with triazole acetamides as anti-Alzheimer and anti-melanogenesis candidates: an in vitro and in silico study.

In this study, new cinnamic acid linked to triazole acetamide derivatives was synthesized and evaluated for anti-Alzheimer and anti-melanogenesis activities. The structural elucidation of all analogs was performed using different analytical techniques, including H-NMR, C-NMR, mass spectrometry, and IR spectroscopy. The synthesized compounds were assessed in vitro for their inhibitory activities against acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and tyrosinase enzymes.

Effect of "normal" versus "mild carpal tunnel syndrome" electrodiagnostic report on surgeon decision and patients clinical outcomes.

Introduction: There exist conflicting electrodiagnostic reports between diagnosing mild carpal tunnel syndrome (CTS) and normal results, depending on the interpretation methods used by electrodiagnosticians. This underscores the necessity for precise clinical guidelines. This study aims to assess how the variation between mild and normal electrophysiological reports impacts (1) subsequent clinical outcomes in patients diagnosed with CTS and (2) physicians' decision-making.

Sargassum glaucescens Extract/Marine-Derived Collagen Blend Sponge and Their Properties for Wound Healing.

Burn wounds are challenging to treat due to considerable tissue damage and fluid loss. Creating wound dressings from natural and biological materials makes it possible to treat wounds and promote rapid epithelialization to speed healing and restore skin function. As a result, the ability of a collagen scaffold (Col) made from rainbow trout (Oncorhynchus mykiss) and putative bioactive phytochemical components from a Sargassum glaucescens (S.

Global, regional, and national burden of primary liver cancer attributable to metabolic risks: an analysis of the Global Burden of Disease Study 1990-2021.

Background: The global burden of metabolic diseases is increasing, but estimates of their impact on primary liver cancer are uncertain. We aimed to assess the global burden of primary liver cancer attributable to metabolic risk factors, including high body mass index (BMI) and high fasting plasma glucose (FPG) levels, between 1990 and 2021.

Methods: The total number and age-standardized rates of deaths and disability-adjusted life years (DALYs) from primary liver cancer attributable to each metabolic risk factor were extracted from the Global Burden of Disease Study 1990-2021.

Prevalence and determinants of self-medication consumption of antibiotics in adults in Iran: a population based cross-sectional study, 2019-2020.

Introduction: The self-medication of antibiotics is a global crisis, posing a significant challenge to healthcare systems worldwide. This study aimed to investigate the frequency of self-medication in the adult population and the factors influencing it.

Methods: This population-based cross-sectional study was conducted in Arak, a city in central Iran, from January 2019 to January 2020.

Evaluating hospital performance with additive DEA and MPI: the Isfahan University of Medical Science case study.

Background: Hospitals are a vital pillar of the health system, and measuring their performance by an appropriate quantitative model is crucial. This study evaluated the performance of hospitals affiliated with Isfahan University of Medical Sciences. It deals with the nature of dynamics (the performance of evaluation indicators over time), examining controllable, uncontrollable, and undesirable input and output indicators.