Introducing photo-crosslinked bio-nanocomposites based on polyvinylidene fluoride/poly(glycerol azelaic acid)--glycidyl methacrylate for bone tissue engineering.

As a glycerol-based polyester, poly(glycerol azelaic acid) (PGAz) has shown great potential for biomedical applications, such as tissue engineering. However, it tends to show low mechanical strength and a relatively fast biodegradation rate, limiting its capability of mimicking and supporting a broad range of hard tissues such as bone. Moreover, the typical thermal curing process of poly(glycerol--diacids) is one of their drawbacks.

Perylene bisimide-based nanocubes for selective vapour phase ultra-trace detection of aniline derivatives.

Rapid and selective detection of biomarkers at trace levels is a highly coveted objective in the early diagnosis of cancer. Herein, we disclose the design and synthesis of a polyhedral oligomeric silsesquioxane (POSS) substituted perylene diimide. This compound is fully characterized in solution by multi nuclear NMR, as well as in gas state by ESI-MS.

Albumin-loaded thermo/pH dual-responsive nanogels based on sodium alginate and poly (N-vinyl caprolactam).

During the past decades, many researchers have tried to encapsulate medicines in biopolymer nanogels as injectable medicines. In the present study, dual-responsive bovine serum albumin (BSA)-loaded nanogels prepared from sodium alginate grafted poly (N-vinyl caprolactam) (PNVCL) have been reported. First, PNVCL-g-sodium alginate (PNVCL-g-Alg) was synthesized through free radical polymerization, and then nanogels were obtained from ionic crosslinking of sodium alginate in the presence of BSA.

Redox-responsive waterborne polyurethane nanocarriers for targeted doxorubicin delivery.

Nanocarriers of different origins that respond to stimuli have been synthesized and used in various biomedical applications, such as intracellular drug delivery. To develop highly efficient nanocarriers, novel clickable and cleavable soybean oil-based polyurethane nanomicelles (CPUM), and polyurethane-hyaluronic acid nanomicelles (CPUM-HA) were prepared. The prepared nanocarriers exhibited controlling self-assembly properties, stimuli-responsiveness, good cytocompatibility, and high loading capacity for doxorubicin (DOX).

Heteroployacid on the composite of boehmite and polyionic liquid as a catalyst for alcohol oxidation and tandem alcohol oxidation Knoevenagel condensation reactions.

Using boehmite as an available and low-cost natural compound, a bi-functional catalytic composite is prepared through vinyl-functionalization of boehmite, followed by polymerization with the as-prepared bis-vinylimidazolium bromide ionic liquid and supporting of phosphotungstic acid. The catalyst was characterized via ICP, XRD, TGA, FTIR, SEM/EDS and elemental mapping analysis and applied for promoting alcohol oxidation reaction and one-pot tandem alcohol oxidation/Knoevenagel condensation reaction in aqueous media under mild reaction condition. The results indicated high catalytic activity of the catalyst for both reactions.

Drug in adhesive transdermal patch containing antibiotic-loaded solid lipid nanoparticles.

The structure of the skin only allows those hydrophobic elements to penetrate through the depth of the skin with low molecular weight (less than 500 Da) and low daily dose (less than 100 mg/day). Skin penetration of many drugs such as antibiotics at a high daily dose remains an unresolved challenge. In this study a transdermal patch using cephalexin as an antibiotic drug model was developed.

Dexamethasone loaded injectable, self-healing hydrogel microspheresbased on UPy-functionalized Gelatin/ZnHAp physical network promotes bone regeneration.

Biopolymer-based injectable hydrogels provide great potential as bone tissue engineering (BTE) scaffolds on account of biocompatibility, and pore interconnectivity that enables delivery of cells and/or signaling molecules for bone repair. Recently, Gelatin hydrogels based on H-bonds were considered in response to concerns around the chemical crosslinking agents. In this study, a self-healing gelatin hydrogel with remarkable compressive and self-healing properties was prepared via formation of quadruple hydrogen bonds between ureidopyrimidinon functional groups, which were substituted on NH groups of gelatin(GelUPy).

XGBoost model as an efficient machine learning approach for PFAS removal: Effects of material characteristics and operation conditions.

Due to the implications of poly- and perfluoroalkyl substances (PFAS) on the environment and public health, great attention has been recently made to finding innovative materials and methods for PFAS removal. In this work, PFAS is considered universal contamination which can be found in many wastewater streams. Conventional materials and processes used to remove and degrade PFAS do not have enough competence to address the issue particularly when it comes to eliminating short-chain PFAS.

PEG-Grafted Graphene/PLLA Nanocomposites: Effect of PEG Chain Length on Crystallization Kinetics of PLLA.

Poly-l-lactic acid (PLLA) nanocomposites containing graphene oxide (GO), modified with different chain lengths of poly(ethylene glycol) (PEG) (400, 2000, and 10 000 g/mol), were prepared by solution casting. The effect of the PEG chain length and nanoparticle content (0.5, 1, and 1.

Modified cellulose paper with photoluminescent acrylic copolymer nanoparticles containing fluorescein as pH-sensitive indicator.

Herein, novel fluorescein mono-acrylate (Flu-Ac) was synthesized and copolymerized with methyl methacrylate and glycidyl methacrylate to produce epoxy-functionalized latex nanoparticles. Fluorescent cellulose paper was then obtained by dip-coating and subsequent heat treatment. Synthesis of Flu-Ac, its incorporation efficiency into the epoxy-functionalized nanoparticles (almost 92 %), spherical morphology of the particles and their sizes (89-93 nm), and optical properties were studied comprehensively.

Pd on cyclotriphosphazen-hexa imine decorated boehmite as an efficient catalyst for hydrogenation of nitro arenes under mild reaction condition.

Cyclotriphosphazen-hexa imine ligand was prepared through successive reactions of phosphonitrilchloride trimer with 4-hydroxybenzaldehyde and (3-aminopropyl) triethoxy silane. The as-prepared ligand was then covalently grafted on boehmite to furnish an efficient support for the immobilization of Pd nanoparticles and synthesis of a novel heterogeneous catalyst for hydrogenation of nitro arenes. The catalytic tests revealed that the catalyst had excellent catalytic activity for hydrogenation of various nitro arenes with different steric and electronic features under mild reaction condition in aqueous media.

Preparation and characterization of Pullulan-based nanocomposite scaffold incorporating Ag-Silica Janus particles for bone tissue engineering.

A nanocomposite bone scaffold was fabricated from pullulan, a natural extracellular polysaccharide. Pullulan (PULL) was blended with polyvinylpyrrolidone (PVP), and a nano-platform with ball-stick morphology, Ag-Silica Janus particles (Ag-Silica JPs), which were utilized to fabricate nanocomposite scaffold with enhanced mechanical and biological properties. The Ag-Silica JPs were synthesized via a one-step sol-gel method and used to obtain synergistic properties of silver and silica's antibacterial and bioactive effects, respectively.

A review on the recent progress, opportunities, and challenges of 4D printing and bioprinting in regenerative medicine.

Four-dimensional (4 D) printing is a novel emerging technology, which can be defined as the ability of 3 D printed materials to change their form and functions. The term 'time' is added to 3 D printing as the fourth dimension, in which materials can respond to a stimulus after finishing the manufacturing process. 4 D printing provides more versatility in terms of size, shape, and structure after printing the construct.

In vitro and in vivo evaluation of nanofibre mats containing extract as a wound dressing.

Objective: The present study aims to create -loaded nanofibre-based wound dressing materials to enhance the wound healing process. is an annual herb native to the Mediterranean region. It is antipyretic, antifungal, antioedema, antidiabetic, anti-inflammatory (wound, oral and pharyngeal mucosa), antispasmodic, treats chronic ocular surface diseases, acts as a stimulant and a diaphoretic.

Efficacy and safety of chitosan-based bio-compatible dressing versus nanosilver (Acticoat ) dressing in treatment of recalcitrant diabetic wounds: A randomized clinical trial.

Chitosan has a biocompatible, biodegradable, and nontoxic nature. The effectiveness of Nano-chitosan films in the field of wound healing has been confirmed previously. The aim of this study was to compare the clinical efficacy and safety of two dressings (chitosan and nanosilver dressings) in the treatment of refractory diabetic wounds.

Designing Hybrid Mesoporous Pr/Tannate-Inbuilt ZIF8-Decorated MoS as Novel Nanoreservoirs toward Smart pH-Triggered Anti-corrosion/Robust Thermomechanical Epoxy Nanocoatings.

For the first time, organic tannic acid (TA) molecules and then inorganic praseodymium (Pr) cations as corrosion inhibitors were successfully loaded into a zeolitic imidazolate framework (ZIF8)-type porous coordination polymer (PCP) decorated on molybdenum disulfide, MoS, (MS)-based transition metal dichalcogenides (TMDs) to create novel hybrid mesoporous Pr/TA-ZIF8@MS nanoreservoirs. Thereafter, the hybrid nanoreservoirs were embedded into the epoxy matrix for the preparation of smart pH-triggered nanocoatings. Characterizations of the Pr/TA-ZIF8@MS nanoreservoirs via Fourier transform infrared (FT-IR), X-ray diffraction (XRD), thermogravimetric (TG), Brunauer-Emmett-Teller (BET), and field emission-scanning electron microscopy (FE-SEM)/energy-dispersive X-ray spectroscopy (EDS) experiments confirmed the fabrication of mesoporous structures comprising Pr/TA interfacial interactions with ZIF8-decorated MS nanoplatelets possessing high thermal stability and compact/dense configuration features with a framework reorientation.

Preparation of Photoswitchable Polyacrylic Nanocomposite Fibers Containing Au Nanorods and Spiropyran: Optical and Plasmonic Properties.

Photoswitchable nanofibers and nanocomposite fibers containing plasmonic nanoparticles have attracted a great deal of interest in optical and plasmonic devices. Herein, photoswitchable poly(methyl methacrylate--vinylimidazole--spiropyran ethyl acrylate) (MVSP) and its copolymer with butyl acrylate (MBVSP) were prepared via emulsion polymerization, and the corresponding nanofibers (MVSP@NF and MBVSP@NF) and nanocomposite fibers (MVSP/Au@NF and MBVSP/Au@NF) containing AuNRs were fabricated through electrospinning. FTIR and H NMR analyses confirmed the progress of the copolymerization reaction.

Decorated magnetic nanoparticles with polyvinyl alcohol brushes modified with metal chelate affinity groups for purification of proteins.

Refining is a serious challenge in the production of recombinant proteins, and this study proposes a new and easy strategy for the synthesis of magnetic affinity nanoparticles. First, the nanoparticles attached to polyvinyl alcohol brushes were synthesized, and then the hydroxyl groups of this polymer were converted to chelate groups. The nanoparticles were examined by (SEM) scanning electron microscopy, (TEM) transmission electron microscopy, (DLS) dynamic light scattering, (FT-IR) Fourier transform infrared, (XRD) X-ray powder diffraction, (VSM) vibrating sample magnetometry, and (TGA) thermal gravimetric analysis.

Migration of Irganox 1010, Irganox 1076, and Titanium dioxide into Doogh and corresponding food simulant from laminated packaging.

Purpose: Doogh is a famous Iranian drink based on fermented milk. Laminated film is one of the most common packaging for this beverage in Iran. So, chemical substances of the packaging may migrate to the Doogh and endanger human health.

Air-to-Air Heat and Moisture Recovery in a Plate-Frame Exchanger Using Composite and Asymmetric Membranes.

The present work studied an air-to-air exchanger comprising a flat plate module with a diagonal channel and a counterflow configuration for the air streams. The objective of this study was to remove moisture and sensible heat from an exhaust air stream by indirect contact with another air stream. The temperature and flow rate of the exhaust air was in the range of 40-80 °C and 1-5 L·min, respectively, and the fresh ambient air to exhaust air flow ratio was 1-5.

Effect of Organoclay Addition on Rheological, Thermal, and Mechanical Properties of Nitrile Rubber/Phenolic Resin Blend.

In this study, the effects of NBR polarity and organoclay addition on the curing, rheological, mechanical, and thermal properties of an NBR/phenolic resin blend were investigated. The samples were prepared using a two-roll mill. The results showed that rheological and tensile properties improved due to the good distribution of nanoparticles, as well as the good compatibility of nitrile butadiene rubber with phenolic resin.

Theoretical and experimental study of the photodegradation of methyl orange in the presence of different morphologies of Au-ZnO using Monte Carlo dynamic simulation.

Herein, a simple approach was formed based on synthesizing different morphologies of ZnO and Au-ZnO as photocatalyst. In this study, ZnO and Au-ZnO were synthesized via a co-precipitation method and fully characterized via scanning electron microscopy (SEM), X-ray diffraction (XRD), and energy-dispersive X-ray spectroscopy (EDX). Three different ratios of Zn:OH (1:2, 1:3, and 1:5) controlled the morphology of samples, which were made into spindle, star, and flower structures, respectively.

Multilayered 3-D nanofibrous scaffold with chondroitin sulfate sustained release as dermal substitute.

Electrospun nanofibers for skin tissue engineering applications face two main challenges. The low thickness of electrospun mats is the main reason for their weak load-bearing performance at clinical applications and limited cell penetration due to their small pore sizes. We have developed multi-layered nanofibrous 3D (M3DN) scaffolds comprising gelatin, polyvinyl alcohol, and chondroitin sulfate (CS) by an electrospinning method and attaching three electrospun layers via ethanol to cause interface fibers to come in contact with each other.

Pd on thermo-responsive composite of silica-coated carbon nanotube and 1-vinyl-3-butylimidazolium-based ionic liquid copolymers as an efficient catalyst for hydrogenation of nitro compounds.

In this work, an ionic liquid-containing thermo-responsive heterogeneous catalyst with utility for promoting hydrogenation of nitro-compounds in aqueous media is developed. To prepare the catalyst, silica-coated carbon nanotubes were synthesized and vinyl-functionalized. The resulted compound was then polymerized with 1-viny-3-butylimidazolium bromide and N-isopropylacrylamide.

Fabrication and Evaluation of A Chondroitin Sulphate-Polycaprolactone Composite Nanofibrous Scaffold for Potential Use in Dermal Tissue Engineering.

Objective: Poly(ε-caprolactone) (PCL) has considerable mechanical and biological properties that make it a good candidate for tissue engineering applications. PCL alongside proteins and polysaccharides, like gelatin (GEL) and chondroitin sulphate (CS), can be used to fabricate composite scaffolds that provide mechanical and biological requirements for skin tissue engineering scaffolds. The aim of this study was fabricating novel composite nanofibrous scaffold containing various ratios of GEL/CS and PCL using co-electrospinning process.