15,000 results match your criteria: "Iran Polymer & Petrochemical Institute[Affiliation]"
J Biomater Sci Polym Ed
December 2024
Department of Biomaterials and Tissue Engineering, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Bone tissue engineering is a promising approach to address the increasing need for bone repair. Scaffolds play a crucial role in providing the structural framework for cell growth and differentiation. 3D printing offers precise control over scaffold design and fabrication.
View Article and Find Full Text PDFTechnol Cancer Res Treat
December 2024
Department of Life Science Engineering, Faculty of New Sciences and Technologies, University of Tehran, Tehran, Iran.
Objectives: This study developed a drug delivery system (DDS) using folic acid (FA)-functionalized chitosan (CS) and poly (lactic-co-glycolic acid) (PLGA) nanocarriers for targeted sodium butyrate (NB) delivery to leukemia cells (NALM6). The goal was to enhance NB's therapeutic efficacy while reducing its cytotoxicity to non-malignant cells.
Methods: FA-CS-PLGA nanocarriers were synthesized and characterized using Fourier-transform infrared spectroscopy (FT-IR), dynamic light scattering (DLS), zeta potential analysis, transmission electron microscopy (TEM), and thermogravimetric analysis (TGA).
Mikrochim Acta
December 2024
Department of Chemistry, Yazd University, Yazd, 89195-741, Iran.
An electrochemical aptasensor has been developed specifically for the sensitive and selective determination of ochratoxin A (OTA), one of the most important mycotoxins. The aptasensor utilizes a glassy carbon electrode that has been modified with toluidine blue (TB) encapsulated in a Zn-based metal-organic framework (TB@Zn-MOF). The results demonstrate that in the presence of OTA, the peak current of the differential pulse voltammogram (DPV) related to TB oxidation is notably decreased.
View Article and Find Full Text PDFBMC Oral Health
December 2024
School of Dentistry, The University of Queensland, Brisbane, Australia.
Background: This randomized clinical trial aimed to evaluate the effect of intracanal cryotherapy with 2-4 °C normal saline irrigation on post-operative pain after single-visit non-surgical root canal retreatment.
Methods: Forty-six single-rooted, single-canal teeth requiring non-surgical root canal retreatment were randomly assigned to two groups (n = 23): a cryotherapy group and a control group. All the treatments were completed during a single visit.
Biomaterials
May 2025
College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu, 610065, China; Department of Endodontics, Department of Orthodontics, State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China. Electronic address:
In medical and biomedical fields, enzyme-mimetic nanomaterials have garnered significant interest as efficacious signal enhancers for biocatalyst-linked immunosorbent assays (BLISA). Despite the burgeoning enthusiasm, engineering artificial biocatalysts that exhibit both exceptional catalytic proficiency and pronounced colorimetric signal output remains a formidable challenge. Inspired by the heme structures and biocatalytic activities of horseradish peroxidase, we introduce the synthesis of vanadium single-atoms (SAV) coordinated artificial peroxidases as BLISA for highly sensitive and selective carcinoembryonic antigen (CEA) immunoassay.
View Article and Find Full Text PDFJ Chromatogr B Analyt Technol Biomed Life Sci
January 2025
Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran. Electronic address:
Here, a zirconium-based metal organic framework-dispersive solid phase extraction method was established as an efficient, robust, and accurate approach for quantifying apixabanin human plasma samples prior to capillary electrophoresis with diode array detection. Various types of metal organic frameworks based on UiO-66-NH were synthesized by altering modulators and solvents and applied as sorbents in the extraction procedure. Among the tested sorbents, UiO-66-NH prepared in dimethylformamide in the presence of acetic acid was found to be the best sorbent in this method for the extraction of apixaban with high extraction efficiency comparable to other types of UiO-66-NH metal organic frameworks.
View Article and Find Full Text PDFArch Dermatol Res
December 2024
Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Int J Biol Macromol
December 2024
Department of Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran; Nanotechnology Research Centre, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran; Leicester School of Pharmacy, De Montfort University, Leicester, UK. Electronic address:
A promising new approach to mitigate the adverse effects of chemotherapeutic drugs on healthy tissues involves combining sonodynamic therapy with topical chemotherapy to enhance the therapeutic efficacy of anticancer drugs. In this study, we introduce a multi-functional in situ chitosan hydrogel (CS) containing silk fibroin nanoparticles (SFNPs) loaded with doxorubicin (DOXSFNPs) and CuO/TiO nanoparticles (CTNPs) for combination therapy. The developed DOXSFNPs exhibited a size of 257 ± 6 nm, a zeta potential of -14.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Riddet Institute, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand. Electronic address:
Plant-derived bioactive polysaccharides (PDBPs), versatile polymers originating from various botanical sources, exhibit a spectrum of biological functionalities crucial for human health. This review delves into the multifaceted roles of these bioactive compounds, elucidating their immune-boosting properties, antioxidant prowess, anti-inflammatory capabilities, and contributions to gut health. Amidst their pivotal roles, the efficiency of PDBPs delivery and bioavailability in the human system stands as a central determinant of their efficacy and utilization.
View Article and Find Full Text PDFJ Drug Target
December 2024
School of Dentistry, North Khorasan University of Medical Sciences, Bojnourd, Iran.
Periodontitis (PD) is a chronic gum illness that may be hard to cure for a number of reasons, including the fact that no one knows what causes it, the side effects of anti-microbial treatment, and how various kinds of bacteria interact with one another. As a result, novel therapeutic approaches for PD treatment must be developed. Additionally, supplementary antibacterial regimens, including local and systemic medication administration of chemical agents, are necessary for deep pockets to assist with mechanical debridement of tooth surfaces.
View Article and Find Full Text PDFBMC Biotechnol
December 2024
Department of Biology, Faculty of Basic Sciences, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran.
This study investigated the ability of Phyllanthus emblica encapsulated within chitosan-coated casein (CS-casein-Amla) nanoparticles to inhibit the growth of multi-drug-resistant Pseudomonas aeruginosa (P. aeruginosa) bacteria and prevent the formation of biofilms. The MDR strains underwent screening, and the morphological characteristics of the resulting nanoparticles were assessed using SEM, DLS, and FTIR.
View Article and Find Full Text PDFBMC Oral Health
December 2024
Department of Oral and Maxillofacial Radiology, School of Dentistry, Iran University of Medical Sciences, Azadi St., Jamalzadeh St., Jamshid Alley, Tehran, 1313883851, Iran.
Background: Enterococcus faecalis (E. faecalis) is the most common microorganism responsible for post-endodontic infections, which can penetrate deep into dentinal tubules. This study aimed to compare the survival of E.
View Article and Find Full Text PDFBMC Endocr Disord
December 2024
Department of Biochemistry, Faculty of Medicine, Iran University of Medical Sciences, P.O. Box: 1449614525, Tehran, Iran.
Int J Biol Macromol
December 2024
Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran; Industrial Biotechnology Research Group, Institute of biotechnology, Ferdowsi University of Mashhad, Mashhad, Iran; Nano Research Center, Ferdowsi University of Mashhad, Mashhad, Iran. Electronic address:
The controlled release of herbicides using new and safe materials can mitigate environmental pollution. Polyhydroxyalkanoate (PHA) is a type of biopolymer that can be produced by various bacteria. It has properties that make it suitable for encapsulation and controlled release applications.
View Article and Find Full Text PDFJ Chem Theory Comput
January 2025
Eduard-Zintl-Institut für Anorganische und Physikalische Chemie, Technical University of Darmstadt, Peter-Grünberg-Str. 8, Darmstadt D-64287, Germany.
We report a concurrent hybrid multiscale simulation method, in which a particle domain is coupled with a surrounding continuum domain. The particle domain consists of a coarse-grained model of poly(lactic acid) and the continuum domain is treated using the finite element method. The coarse-grained model is derived from an atomistic model, using the iterative Boltzmann inversion scheme.
View Article and Find Full Text PDFLangmuir
December 2024
Department of Physical Chemistry, Faculty of Basic Science, Tarbiat Modares University, P.O. Box 14115-175, Tehran 21, I.R. of Iran.
The aim of this research is to explore the effectiveness of epoxy-resin@polypyrole composites as a corrosion inhibitor when applied as a coating on carbon steel 1018 in a 3.5 wt % sodium chloride electrolyte solution. The anticorrosion properties of these composite coatings can be optimized by manipulating their morphology.
View Article and Find Full Text PDFHeliyon
December 2024
Research Center for Environmental Health Technology, Iran University of Medical Sciences, Tehran, Iran.
Today, plastic plays a pervasive role in everyday life. Their improper disposal can create ongoing environmental challenges. Polyurethane (PU) is a polymer with elastomeric properties that exhibits significant adhesion and durability.
View Article and Find Full Text PDFMaterials (Basel)
November 2024
Razi Metallurgical Research Center, No. 8, Fernan St., HajGhasem Asghari Blvd., Shahre Ghods Entrance (Sorkhe Hesar), Tehran P.O. Box 39, Iran.
This research investigated the sound insulation performance of 3D woven hybrid fabric-reinforced composites using natural fibers, such as jute, along with E-glass and biomass derived from agro-waste, e.g., coffee husk and waste palm fiber.
View Article and Find Full Text PDFPolymers (Basel)
November 2024
City of London Dental School, University of Bolton, London BL3 5AB, UK.
Polymers have become essential in advancing bone tissue engineering, providing adaptable bone healing and regeneration solutions. Their biocompatibility and biodegradability make them ideal candidates for creating scaffolds that mimic the body's natural extracellular matrix (ECM). However, significant challenges remain, including degradation by-products, insufficient mechanical strength, and suboptimal cellular interactions.
View Article and Find Full Text PDFBiomed Mater
December 2024
Department of Polymer Processing, Iran Polymer and Petrochemical Institute, Department of Polymer Processing, Iran Polymer and Petrochemical Institute, P.O. Box 14965-115, Tehran, Iran, Tehran, 1497713115, Iran (the Islamic Republic of).
Regenerative medicine by applying tissue engineering and cell transplantation has provided a new door in wound healing. This study tracked healing effect of human Wharton's jelly stem cells (WJSCs) labeled with superparamagnetic iron oxide nanoparticles (SPIONs) seeded onto poly vinyl alcohol/chitosan/carbon nanotubes (PVA/CS/CNT) in burn wounds by magnetic resonance imaging (MRI) and Prussian Blue staining. .
View Article and Find Full Text PDFACS Appl Bio Mater
December 2024
Caspian Faculty of Engineering, College of Engineering, University of Tehran, Rezvanshar, Guilan 43861-91836, Iran.
A promising approach for wound treatment is using multilayer wound dressings that offer multifunctional properties. In this study, a bilayered electrospun/hydrogel gelatin-based scaffold integrated with honey and curcumin was developed to treat wounds under an in vivo study. The first layer consisted of an enzymatic cross-linked gelatin hydrogel containing honey and curcumin, which gelatin/PCL nanofibers reinforced.
View Article and Find Full Text PDFNanomedicine (Lond)
January 2025
Advanced Laboratory of Nanocarriers Synthesis, Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Background: Poly (β-amino Ester) nanocarriers show promise for gene therapy, but their effectiveness can be limited by the environment within the body. This study aims to understand how common cell culture media components affect optimized PBAE nanocarrier performance in gene delivery.
Methods: Optimized PBAE was synthesized based on Michael addition reaction and characterized by different assays, this study employed techniques like DLS and TEM to characterize PBAE nanocarriers, followed by cellular uptake analysis (flow cytometry and confocal imaging) and evaluation of gene expression under different polymer/DNA ratio ratios and media conditions.
Compr Rev Food Sci Food Saf
January 2025
School of Food Science and Engineering, Hainan University, Haikou, China.
In recent years, biopolymer-based food packaging films have emerged as promising alternatives to petroleum-based plastic food packaging films. Various additives have been explored to enhance their properties, and one such group of additives is natural plant aldehydes. These aldehydes are commonly employed to improve the antibacterial and antioxidant properties of biopolymer-based food packaging films.
View Article and Find Full Text PDFMol Biochem Parasitol
December 2024
Department of Clinical Pharmacy, School of Pharmacy, Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran. Electronic address:
Cutaneous leishmaniasis is considered as one of the most concerns of the World Health Organization (WHO). The main objective of this study was to use polycaprolactone (PCL) nanofiber scaffolds in order to provide a topical drug delivery system capable of delivering glucantime (glu) and quercetin (qur) to cutaneous leishmaniasis wounds. First, PCL/glu/qur, PCL/glu, and PCL/qur nanofibers were prepared by an electrospinning method followed by characterization through scanning electron microscopy (SEM) and fourier transform infrared spectroscopy (FTIR).
View Article and Find Full Text PDFChemosphere
February 2025
Environmental Engineering and Management Research Group, Ton Duc Thang University, Ho Chi Minh City, Viet Nam; Faculty of Environment and Labour Safety, Ton Duc Thang University, Ho Chi Minh City, Viet Nam.