Mitochondrial haplogroups and control region polymorphisms in Kaposi's sarcoma patients.

Inflammation and reactive oxygen species (ROS) production have recently considered as key mechanisms in the pathogenesis of Kaposi's sarcoma (KS). Since mitochondria are the major source of ROS production, this organelle may play a main role in KS development. However, there are no studies on mtDNA variations and haplogroups in this area.

Risk factors of viral hepatitis: yet to explore.

Background And Aims: The safety of donated blood is the most vital concern of a blood transfusion organization. Hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) screening for blood transfusion products has gained more importance where knowing the prevalence rate will help health policy makers. In this paper, we will evaluate the prevalence of viral infection in donated blood in the province of Qazvin in 2009.

Blood safety concerns in the Eastern Mediterranean region.

Blood transfusion is a life-saving component of health care systems. Nevertheless, it can also be a quick and easy method of exposing patients to risks, particularly the transmission of infectious agents to recipients. Despite substantial improvements in the safety of transfusion services worldwide, the presence of paid and replacement blood donors are still of cause concern for ensuring sustainable safe blood donations.

Successful exclusion of blood-borne viral disease in blood donors.

Background: All blood transfusion services have various rules to insure that blood products are kept safe for transfusion. Donor selection is crucial in providing safe blood. We propose in our study to determine the influence of donor selection on blood safety.

The High Yield Expansion and Megakaryocytic Differentiation of Human Umbilical Cord Blood CD133(+) Cells.

Objective: Despite of many benefits, umbilical cord blood (UCB) hematopoietic stem cell (HSC) transplantation is associated with low number of stem cells and slow engraftment; in particular of platelets. So, expanded HSCs and co-transfusion of megakaryocyte (MK) progenitor cells can shorten this period. In this study, we evaluated the cytokine conditions for maximum expansion and MK differentiation of CD133(+) HSCs.

Chromosomal abnormalities in infertile men referred to iran blood transfusion organization research center.

Introduction: The prevalence of somatic chromosomal abnormalities in infertile male individuals has been reported to vary in different literatures. The aim of this study was to investigate the frequency of chromosomal aberrations among infertile men referred to the Cytogenetic Laboratory of Iran Blood Transfusion Organization Research Centre (IBTO).

Materials And Methods: Chromosomal analysis was performed on phytohemag-glutinin (PHA)-stimulated peripheral lymphocyte cultures of 1052 infertile men using standard cytogenetic methods.