Stem cell therapy for bladder regeneration: A comprehensive systematic review.

Tissue engineering has been considered a potential choice for urinary system reconstruction. Here, we aim to a broad spectrum of employed stem cells in bladder regeneration by performing a comprehensive systematic review. In January 2024, we searched Scopus, PubMed, and Embase databases for studies that tried bladder regeneration by tissue engineering using stem cells.

Subdural empyema in patient with SARS-CoV-2 positivity: A rare case report of 3 patients.

Coronavirus disease 2019 (COVID-19) is a viral pandemic and a matter of concern. It also mimics viral pneumonia with cough and fever but also causes severe sequels and various complications. Subdural empyema is a very rare brain infection presenting mostly with fever, weakness, and altered level of consciousness, and has been recently noted as a new complication of COVID-19.

Controlled bioreduction of silver ions to nanosized particles on a porous magnetic-biopolymer of carboxymethyl cellulose, FeO/CMC-Ag NPs, serving as a sustainable nanocatalyst.

A magnetic-biopolymer composite of carboxymethyl cellulose (CMC), designated as FeO@CMC, was synthesized featuring remarkable stability and an active surface with a green biosynthetic method. This composite was engineered to serve as a substrate for stabilizing silver nanoparticles (Ag NPs) with enhanced functional properties. The catalytic efficacy of the nanocatalyst, incorporating Ag NPs at concentrations of 3%, 7%, and 10%, was evaluated for the reduction of the toxic compound 4-nitrophenol to the beneficial 4-aminophenol.

Transition metal-catalyzed cross-coupling reactions of -aryl-2-aminopyridines.

Due to the presence of the pyridyl directing group, -aryl-2-aminopyridines can quickly form stable complexes with metals, leading to cyclization and functionalization reactions. A large number of N-heterocycles and nitrogen-based molecules can be easily constructed this direct and atom-economical cross-coupling strategy. In this review, we have highlighted the transformations of -aryl-2-aminopyridines in the presence of various transition metal catalysts, such as palladium, rhodium, iridium, ruthenium, cobalt and copper.

Exploring the capabilities of 2-alkynyl aryl/benzyl azides: synthesis approaches for indoles, quinolines, and their derivatives transition metal catalysis.

In recent research, quinoline and indole structures have gained recognition for their significant clinical relevance and effectiveness. These compounds are known for their wide-ranging pharmacological effects, which include anticancer, antibacterial, antifungal, antiviral, and anti-inflammatory properties. Researchers have successfully implemented a variety of innovative synthetic strategies, leading to the creation of numerous compounds that display fascinating biological activities in diverse fields.

A comparison between 64-projection and 32-projection myocardial perfusion scintigraphy.

Aims: While most clinical guidelines recommend using a 64-projection view technique, some protocols do not specify a preference between 32-projection and 64-projection methods for conducting myocardial perfusion scintigraphy (MPS), which shows the lack of consensus in this matter. Nevertheless, these guidelines and protocols have not provided us with compelling evidence to support why the 64-projection technique is usually chosen. Thus, we aimed to determine if there is a significant difference between them in the assessment of cardiac perfusion and functional indices.

Investigation of the expression level of methylated septin 9 gene and serological carcinoembryonic antigen to diagnose colorectal cancer. A meta-analysis study.

Introduction: Colorectal cancer (CRC) is a rising threat, necessitating accurate early diagnosis.

Aim: This meta-analysis scrutinised methylated septin 9 (SEPT9) and carcinoembryonic antigen (CEA) in CRC.

Methods: From January 2012 to December 2022, databases including PubMed and Google Scholar were explored for English publications.

Case report: an infant with late-onset meningitis caused by Escherichia coli.

Background: Meningitis is highly prevalent in infant because their immune system is immature and they have less resistance to diseases. Among bacterial agents, is recognized as one of the most important causes of meningitis in infants.

Case Presentation: Herein, we report a case of late-onset meningitis, caused by (Patient:17-day-old female infant).

The prospect of using nanotechnology to prevent and treat infections caused by .

() is an opportunistic intracellular pathogen that causes listeriosis in human and leads to high mortality rate. is resistant to various antibiotics due to its ability to form biofilm. Designing a new generation of antibiotics is a very expensive and time-consuming process.

Cell size has pervasive effects on the functional composition and morphology of leaves: a case study in Rhododendron (Ericaceae).

The leaf economics spectrum (LES) characterizes a tradeoff between building a leaf for durability versus for energy capture and gas exchange, with allocation to leaf dry mass per projected surface area (LMA) being a key trait underlying this tradeoff. However, regardless of the biomass supporting the leaf, high rates of gas exchange are typically accomplished by small, densely packed stomata on the leaf surface, which is enabled by smaller genome sizes. Here, we investigate how variation in genome size-cell size allometry interacts with variation in biomass allocation (i.

Innovative applications of MXenes in dialysis: enhancing filtration efficiency.

MXenes, a family of two-dimensional transition metal carbides and nitrides, exhibit exceptional properties such as high electrical conductivity, large surface area, and chemical versatility, making them ideal candidates for various dialysis applications. One prominent application of MXenes lies in the efficient removal of toxic metals and harmful dyes from wastewater. Their unique structure allows for rapid adsorption and selective separation, significantly improving purification processes.

Liver Transplant Outcome in Chanarin-Dorfman Syndrome: A Rare Lipid Storage Disease.

Chanarin-Dorfman syndrome is a multisystem inherited metabolic disorder characterized by congenital ichthyosis and lipid droplet accumulation in various organs, including the liver, muscles, and skin. The accumulation of lipids in the liver can lead to cirrhosis, liver failure, and even hepatocellular carcinoma. Here, we present a 17-year-old girl who underwent a deceased donor liver transplant to treat uncompensated cirrhosis due to Chanarin-Dorfman syndrome.

Effect of Transplanted Liver Fat Percentage on Organ Survival: A Retrospective Review.

Objectives: Liver transplant is the most effective therapeutic option for patients with end-stage liver disease, nonalcoholic steatohepatitis, and acute liver failure. We evaluated whether the percentage of hepatic fat percentage affected transplant outcomes to determine whether livers with varying severity of macrosteatosis should be considered suitable for donation.

Materials And Methods: We analyzed data from 381 patients with liver failure who received liver transplant at Montaseriyeh Hospital in Mashhad, Iran, between 2013 and 2022.

Acinetobacter baumannii Bloodstream Infections in Hematopoietic Stem Cell Transplant Recipients: A Worldwide Systematic Review.

Objectives: Bloodstream infection is one of the main causes of death in hematopoietic stem cell transplant recipients. Acinetobacter baumannii is a bacteria associated with bloodstream infection and subsequent death from high antibiotic resistance in this group of patients. We evaluated bloodstream infections of Acinetobacter baumannii in hematopoietic stem cell transplant recipients.

A Comparative Review on the Production of Factor VIII in Human and Non-human Hosts.

Hemophilia A (HA) is an inherited condition that is characterized by a lack of coagulation factor VIII (FVIII), which is needed for blood clotting. To produce recombinant factor VIII (rFVIII) for treatment, innovative methods are required. This study presents a thorough examination of the genetic engineering and biotechnological methods that are essential for the production of this complex process.

Nanosystems for Intranasal Delivery of Therapeutics in Psychiatric Disorders.

Due to the blood-brain barrier (BBB) and issues with oral and other traditional routes of administration, psychiatric disorders present significant challenges in getting therapeutics into the brain. The nose-to-brain pathway, also known as intranasal delivery, has shown promise in overcoming these barriers since it targets the brain directly and bypasses the BBB. This review explores nanocarriers' potential for intranasal delivery of therapeutics in the treatment of psychiatric disorders.

Association between nursing workload and staff size with the occurrence of adverse events and deaths of patients with COVID-19: A retrospective cohort study.

Background: The safety of patients in the intensive care unit (ICU) is significantly impacted by inadequate staffing of nursing professionals to meet the demand for care of critically ill patients. COVID-19 patients increased nurses' workload, particularly in high-intensity care settings like the ICU.

Aim: To evaluate the association of workload and number of patients per nursing professional with the occurrence of adverse events and death in critically ill patients with COVID-19 in the ICU.

Exploration of Polyhydroxybutyrate (PHB) Production Potential of Photosynthetic Microbes: A Sustainable Source of Bioplastic.

Introduction: The present study examined Polyhydroxy butyrate production (PHB) potential of different photosynthetic microbes such as Chlorella vulgaris, Scenedesmus obliquus and Rhodobacter capsulatus-PK under different nutrient conditions. Biodegradable bioplastics, such as Poly-β-hydroxybutyrates (PHB), derived from these microbes provide a sustainable alternative to conventional petroleum-based nondegradable plastics.

Background: As the demand for clean and sustainable alternatives rises, bio-plastic is gaining attention as a viable substitute to conventional plastics.

Presence of the Anopheles culicifacies complex species A in southeast Iran.

Background: The Anopheles culicifacies complex is one of the most important malaria vectors in Southeast Asia and Southeastern Iran. Although the sibling species within this complex are morphologically indistinguishable, they differ significantly in their disease transmission potential, blood-feeding behaviour, and other biological traits. Cytogenetic and chromosomal studies have identified five sibling species within this complex: A, B, C, D, and E.

Sero-molecular prevalence of toxoplasmosis in hemodialysis and peritoneal dialysis patients in Markazi Province, Iran.

Background: Infectious diseases, particularly parasitic infections such as toxoplasmosis, contribute significantly to the morbidity and mortality of hemodialysis patients. Toxoplasma gondii infection poses serious risks, especially to immunocompromised individuals. This study aimed to assess the prevalence of latent toxoplasmosis in dialysis patients in Markazi Province, Iran.

Exploring strategies to enhance patient safety in spine surgery: a review.

Patient safety is the foundation of spine surgery, where the intricate nature of spinal procedures and the unique risks involved call for exceptional diligence and comprehensive protocols. In this high-stakes field, developing and implementing rigorous safety protocols is not only vital for minimizing complications but also for achieving the best possible outcomes and strengthening the confidence patients have in their care team. Each patient entrusts their well-being to their surgical team.

Crosstalk between non-coding RNAs and programmed cell death in colorectal cancer: implications for targeted therapy.

Background: Colorectal cancer (CRC) remains one of the most common causes of cancer-related mortality worldwide. Its progression is influenced by complex interactions involving genetic, epigenetic, and environmental factors. Non-coding RNAs (ncRNAs), including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), have been identified as key regulators of gene expression, affecting diverse biological processes, notably programmed cell death (PCD).

Association between Mediterranean diet and metabolic health status among adults was not mediated through serum adropin levels.

Background: Prevalence of metabolic disorders has been increased in recent years around the world. The relationship between Mediterranean diet (MD) with metabolic health status and serum adropin levels has been less examined in Iranian adults. We investigated the association between MD compliance with metabolic health status and adropin hormone in Iranian adults.

Enhancing Food Security via selecting Superior Camelina (Camelina sativa L.) parents: a positive approach incorporating pheno-morphological traits, fatty acids composition, and Tocopherols Content.

Background: Preserving plant genetic resources is essential for tackling global food security challenges. Effectively meeting future agricultural demands requires comprehensive and efficient assessments of genetic diversity in breeding programs and germplasm from gene banks. This research investigated the diversity of pheno-morphological traits, along with the fatty acid and tocopherol content and composition, in 135 double haploid lines of camelina.